Helicase structure and mechanism

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Story, 1992, Structure of the recA protein-ADP complex, Nature, 355, 374, 10.1038/355374a0

Korolev, 1997, Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP, Cell, 90, 635, 10.1016/S0092-8674(00)80525-5

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Korolev, 1998, Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases, Protein Sci, 7, 605, 10.1002/pro.5560070309

Machius, 1999, Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus, Proc Natl Acad Sci USA, 96, 11717, 10.1073/pnas.96.21.11717

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Theis, 1999, Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair, EMBO J, 18, 6899, 10.1093/emboj/18.24.6899

Tanner, 2001, DExD/H box RNA helicases: from generic motors to specific dissociation functions, Mol Cell, 8, 251, 10.1016/S1097-2765(01)00329-X

Benz, 1999, Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae — the prototype of the DEAD box protein family, Structure, 7, 671, 10.1016/S0969-2126(99)80088-4

Johnson, 1999, Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase, RNA, 5, 1526, 10.1017/S1355838299991410

Caruthers, 2000, Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase, Proc Natl Acad Sci USA, 97, 13080, 10.1073/pnas.97.24.13080

Story, 2001, Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii, Proc Natl Acad Sci USA, 98, 1465, 10.1073/pnas.98.4.1465

Egelman, 1995, Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases, Proc Natl Acad Sci USA, 92, 3869, 10.1073/pnas.92.9.3869

Sawaya, 1999, Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7, Cell, 99, 167, 10.1016/S0092-8674(00)81648-7

Singleton, 2000, Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides, Cell, 101, 589, 10.1016/S0092-8674(00)80871-5

Niedenzu, 2001, Crystal structure of the hexameric replicative helicase RepA of plasmid RSF1010, J Mol Biol, 306, 479, 10.1006/jmbi.2000.4398

Miyata, 2000, Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopy, J Struct Biol, 131, 83, 10.1006/jsbi.2000.4290

Putnam, 2001, Structure and mechanism of the RuvB Holliday junction branch migration motor, J Mol Biol, 311, 297, 10.1006/jmbi.2001.4852

Yamada, 2001, Crystal structure of the Holliday junction migration motor protein RuvB from Thermus thermophilus HB8, Proc Natl Acad Sci USA, 98, 1442, 10.1073/pnas.031470598

Velankar, 1999, Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism, Cell, 97, 75, 10.1016/S0092-8674(00)80716-3

Story, 1992, The structure of the E. coli RecA protein monomer and polymer, Nature, 355, 318, 10.1038/355318a0

Bateman, 2000, The Pfam Protein Families Database, Nucleic Acids Res, 28, 263, 10.1093/nar/28.1.263

Soultanas, 1999, DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase, J Mol Biol, 290, 137, 10.1006/jmbi.1999.2873

Cho, 1998, Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNA, J Biol Chem, 273, 15045, 10.1074/jbc.273.24.15045

Kim, 1998, Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding, Structure, 6, 89, 10.1016/S0969-2126(98)00010-0

Yao, 1999, Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase, Structure Fold Des, 7, 1353, 10.1016/S0969-2126(00)80025-8

Pause, 1992, Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A, EMBO J, 11, 2643, 10.1002/j.1460-2075.1992.tb05330.x

Dillingham, 1999, Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation, Nucleic Acids Res, 27, 3310, 10.1093/nar/27.16.3310

Dillingham, 2001, Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase, Proc Natl Acad Sci USA, 98, 8381, 10.1073/pnas.131009598

Pause, 1993, The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis, Mol Cell Biol, 13, 6789, 10.1128/MCB.13.11.6789

Bird, 1998, Characterisation of Bacillus stearothermophilus PcrA helicase: evidence against an active rolling mechanism, Nucleic Acids Res, 26, 2686, 10.1093/nar/26.11.2686

Soultanas, 2000, Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism, EMBO J, 19, 3799, 10.1093/emboj/19.14.3799

Dillingham, 2000, Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed, Biochemistry, 39, 205, 10.1021/bi992105o

Hsieh, 1999, A two-site kinetic mechanism for ATP binding and hydrolysis by E. coli Rep helicase dimer bound to a single-stranded oligodeoxynucleotide, J Mol Biol, 288, 255, 10.1006/jmbi.1999.2666

Kraulis, 1991, MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures, J Appl Crystallogr, 24, 946, 10.1107/S0021889891004399

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