Heavy metal stress and responses in plants

N.-H. Ghori1, T. Ghori2, Muhammad Qasim Hayat1, Sameen Ruqia Imadi3, Alvina Gul2, Volkan Altay4, Münir Öztürk5
1School of Agriculture and Environmental Sciences, The University of Western Australia, Perth, Australia
2Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan
3Commission on Science and Technology for Sustainable Development in the South, Islamabad, Pakistan
4Biology Department, Faculty of Science and Arts, Hatay Mustafa Kemal University, Hatay, Turkey
5Botany Department & Centre for Environmental Studies, Ege University, Izmir, Turkey

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Abolghassem E, Ding Y, Farzad M, Xie Y (2018) Antioxidant response of bamboo (Indocalamus latifolius) as affected by heavy metal stress. J Elementol 23(1):341–352

Adrees M, Ali S, Rizwan M, Zia-ur-Rehman M, Ibrahim M, Abbas F, Farid M, Qayyum MF, Irshad MK (2015) Mechanisms of silicon-mediated alleviation of heavy metal toxicity in plants: a review. Ecotoxicol Environ Saf 119:186–197

Adriano DC (1986) Elements in the terrestrial environment. Springer, Berlin

Ahmad P, Ozturk M, Gucel S (2012) Oxidative damage and antioxidants induced by heavy metal stress in two cultivars of mustard (Brassica juncea L.) plants. Fresenius Environ Bull 21(10):2953–2961

Aksoy A, Ozturk M (1996) Phoenix dactylifera as a biomonitor of heavy metal pollution in Turkey. J Trace Microprobe Tech 14(3):605–614

Aksoy A, Ozturk M (1997) Nerium oleander as a biomonitor of lead and other heavy metal pollution in mediterranean environments. Sci Total Environ 205:145–150

Aksoy A, Celik A, Ozturk M, Tulu M (2000) Roadside plants as possible indicators of heavy metal pollution in Turkey. Chemia I Inzynieria Ekologiczna 7(11):1152–1162

Alaraidh IA, Alsahli AA, Razik ESA (2018) Alteration of antioxidant gene expression in response to heavy metal stress in Trigonella foenum-graecum L. S Afr J Bot 115:90–93

Alharbi OM, Khattab RA, Ali I (2018) Health and environmental effects of persistent organic pollutants. J Mol Liq 263:442–453

Ali I, Aboul-Enein HY (2002) Speciation of arsenic and chromium metal ions by reversed phase high performance liquid chromatography. Chemosphere 48(3):275–278

Ali I, Aboul-Enein HY (eds) (2006) Instrumental methods in metal ion speciation. CRC Press, Boca Raton

Ali I, Jain CK (2004) Advances in arsenic speciation techniques. Int J Environ Anal Chem 84(12):947–964

Ali I, Aboul-Enein HY, Gupta VK (2009) Nanochromatography and nanocapillary electrophoresis: pharmaceutical and environmental analyses. Wiley, Hoboken

Ali I, Khan TA, Asim M (2011) Removal of arsenic from water by electrocoagulation and electrodialysis techniques. Sep Purif Rev 40(1):25–42

Ali I, Gupta VK, Khan TA, Asim M (2012a) Removal of arsenate from aqueous solution by electro-coagulation method using Al–Fe electrodes. Int J Electrochem Sci 7:1898–1907

Ali I, Khan TA, Asim M (2012b) Removal of arsenate from groundwater by electrocoagulation method. Environ Sci Pollut Res 19(5):1668–1676

Ali I, Asim M, Khan TA (2013) Arsenite removal from water by electro-coagulation on zinc–zinc and copper–copper electrodes. Int J Environ Sci Technol 10(2):377–384

Ali I, Al-Othman ZA, Alwarthan A, Asim M, Khan TA (2014) Removal of arsenic species from water by batch and column operations on bagasse fly ash. Environ Sci Pollut Res 21(5):3218–3229

Ali I, AL-Othman ZA, Sanagi MM (2015) Green synthesis of iron nano-impregnated adsorbent for fast removal of fluoride from water. J Mol Liq 211:457–465

Ali I, AL-Othman ZA, Alwarthan A (2016a) Molecular uptake of congo red dye from water on iron composite nano particles. J Mol Liq 224:171–176

Ali I, Alothman ZA, Al-Warthan A (2016b) Sorption, kinetics and thermodynamics studies of atrazine herbicide removal from water using iron nano-composite material. Int J Environ Sci Technol 13(2):733–742

Ali I, Al-Othman ZA, Al-Warthan A (2016c) Removal of secbumeton herbicide from water on composite nanoadsorbent. Desalin Water Treat 57(22):10409–10421

Ali I, Al-Othman ZA, Alharbi OM (2016d) Uptake of pantoprazole drug residue from water using novel synthesized composite iron nano adsorbent. J Mol Liq 218:465–472

Ali I, AL-Othman ZA, Alwarthan A (2016e) Green synthesis of functionalized iron nano particles and molecular liquid phase adsorption of ametryn from water. J Mol Liq 221:1168–1174

Ali I, AL-Othman ZA, Alwarthan A (2016f) Synthesis of composite iron nano adsorbent and removal of ibuprofen drug residue from water. J Mol Liq 219:858–864

Ali I, Suhail M, Basheer AA (2017a) Advanced spiral periodic classification of the elements. Chem Int 3:220–224

Ali I, Alothman ZA, Alwarthan A (2017b) Supra molecular mechanism of the removal of 17-β-estradiol endocrine disturbing pollutant from water on functionalized iron nano particles. J Mol Liq 241:123–129

Ali I, Alharbi OM, Alothman ZA, Badjah AY, Alwarthan A (2018) Artificial neural network modelling of amido black dye sorption on iron composite nano material: kinetics and thermodynamics studies. J Mol Liq 250:1–8

Ashraf M, Ozturk M, Ahmad MSA (eds) (2010a) Plant adaptation and phytoremediation. Springer, New York, p 481

Ashraf M, Ozturk M, Ahmad MSA (2010b) Toxins and their phytoremediation. In: Ashraf M, Ozturk M, Ahmad MSA (eds) Plant adaptation and phytoremediation. Springer, Dordrecht, pp 1–34

Ashraf MY, Roohi M, Iqbal Z, Ashraf M, Ozturk M, Gucel S (2015) Cadmium (Cd) and lead (Pb) induced inhibition in growth and alteration in some biochemical attributes and mineral accumulation in mung bean [Vigna radiata (L.) Wilczek]. Commun Soil Sci Plant Anal 47:405–413

Assche FV, Clijsters H (1990) Effects of metals on enzyme activity in plants. Plant Cell Environ 13(3):195–206

Aydinalp C, Marinova S (2009) The effects of heavy metals on seed germination and plant growth on alfalfa plant (Medicago sativa). Bulg J Agric Sci 15(4):347–350

Aziz H, Sabir M, Ahmad HR, Aziz T, Zia-ur-Rehman M, Hakeem KR, Ozturk M (2015) Alleviating effect of calcium on nickel toxicity in rice. CLEAN-Soil Air Water 43(6):901–909

Aziz MA, Ahmad HR, Corwin DL, Sabir M, Ozturk M, Hakeem KR (2016) Influence of farmyard manure on retention and availability of nickel, zinc and lead in metal-contaminated calcareous loam soils. J Environ Eng Landsc Manag 25(3):289–296

Barconi D, Bernardini G, Santucci A (2011) Linking protein oxidation to environmental pollutants: redox proteome approaches. J Proteom 74(11):2324–2337

Bargmann BO, Munnik T (2006) The role of phospholipase D in plant stress responses. Curr Opin Plant Biol 9:515–522

Bartels S, Besteiro MAG, Lang D, Ulm R (2010) Emerging functions for plant MAP kinase phosphatases. Trends Plant Sci 15:322–329

Basheer AA (2018a) Chemical chiral pollution: impact on the society and science and need of the regulations in the 21st century. Chirality 30(4):402–406

Basheer AA (2018b) New generation nano-adsorbents for the removal of emerging contaminants in water. J Mol Liq 261:583–593

Baxter A, Mittler R, Suzuki N (2014) ROS as key players in plant stress signalling. J Exp Bot 65(5):1229–1240

Bellomo G, Palladini G, Vairetti M (1997) Intranuclear distribution, function and fate of glutathione and glutathione-S-conjugate in living rat hepatocytes studied by fluorescence microscopy. Microsc Res Tech 36:243–252

Boonyapookana B, Upatham ES, Kruatrachue M, Pokethitiyook P, Singhakaew S (2002) Phytoaccumulation and phytotoxicity of cadmium and chromium in duckweed Wolffia globosa. Int J Phytoremed 4:87–100

Bouazizi H, Jouili H, Geitmann A, Ferjani EEI (2010) Copper toxicity in expanding leaves of Phaseolus vulgaris L.: antioxidant enzyme response and nutrient element uptake. Ecotoxicol Environ Saf 73:1304–1308

Burakova EA, Dyachkova TP, Rukhov AV, Tugolukov EN, Galunin EV, Tkachev AG, Ali I (2018) Novel and economic method of carbon nanotubes synthesis on a nickel magnesium oxide catalyst using microwave radiation. J Mol Liq 253:340–346

Celik Sh, Yucel E, Celik S, Gucel S, Ozturk M (2010) Carolina poplar (Populus x canadensis Moench) as a biomonitor of trace elements in the West Black Sea region of Turkey. J Environ Biol 31(Special Issue):225–232

Cempel M, Nikel G (2006) Nickel: a review of its sources and environmental toxicology. Pol J Environ Stud 15(3):375–382

Chakravarty B, Srivastava S (1992) Toxicity of some heavy metals in vivo and in vitro in Helianthus annuus. Mutat Res 283:287–294

Chao YY, Hsu YT, Kao CH (2009) Involvement of glutathione in heat shock- and hydrogen peroxide-induced cadmium tolerance of rice (Oryza sativa L.) seedlings. Plant Soil 318(1–2):37–45

Chaplen FWR (1998) Incidence and potential implications of the toxic metabolite methylglyoxal in cell culture: a review. Cytotechnology 26(3):173–183

Chen CC, Dixon JB, Turner FT (1980) Iron coatings on rice roots: morphology and models of development. Soil Sci Soc Am J 44:1113–1119

Chen F, Wang F, Wu F, Mao W, Zhang G, Zhou M (2010) Modulation of exogenous glutathione in antioxidant defense system against Cd stress in the two barley genotypes differing in Cd tolerance. Plant Physiol Biochem 48(8):663–672

Cobbett C, Goldsbroughn P (2002) Phytochelatins and metallothioneins: roles in heavy metal detoxification and homeostasis. Annu Rev Plant Biol 53:159–182

Cunningham RP (1997) DNA repair: caretakers of the genome? Curr Biol 7:576–579

Curie C, Alonso JM, Le Jean M, Ecker JR, Briat JF (2000) Involvement of NRAMP1 from Arabidopsis thaliana in iron transport. Biochem J 347:749–755

Dağhan H, Ozturk M (2015) Soil pollution in Turkey and remediation methods. In: Hakeem K, Sabir M, Ozturk M, Mermut A (eds) Soil remediation and plants: prospects and challenges. Elsevier, New York, pp 287–312

Dehghani MH, Sanaei D, Ali I, Bhatnagar A (2016) Removal of chromium (VI) from aqueous solution using treated waste newspaper as a low-cost adsorbent: kinetic modeling and isotherm studies. J Mol Liq 215:671–679

Delhaize E, Ryan PR, Randall RJ (1993) Aluminum tolerance in wheat (Triticum aestivum L.). II. Aluminum stimulated excretion of malic acid from root apices. Plant Physiol 103(3):695–702

Diáz J, Bernal A, Pomar F, Merino F (2001) Induction of shikimate dehydrogenase and peroxidase in pepper (Capsicum annum L.) seedlings in response to copper stress and its relation to lignification. Plant Sci 161:179

DiDonato RJ Jr, Roberts LA, Sanderson T, Eisley RB, Walker EL (2004) Arabidopsis Yellow Stripe-Like2(YSL2): a metal-regulated gene encoding a plasma membrane transporter of nicotianamine-metal complexes. Plant J 39:403–414

El Msehli S, Lambert A, Cresp BF, Hopkins J, Boncompagni E, Smiti SA, Herouart D, Frendo P (2011) Crucial role of (homo)glutathione in nitrogen fixation in Medicago truncatula nodules. New Phytol 192:496–506

Emamverdian A, Ding Y, Mokhberdoran F, Xie Y (2015) Heavy metal stress and some mechanisms of plant defense response. Sci World J 2015:1–18

Emery L, Whelan S, Hirschi KD, Pittman JK (2012) Phylogenetic analysis of Ca2+/cation antiporter genes and insights into their evolution in plants. Front Plant Sci 3:1

Espartero J, Sanchez-Aguayo I, Pardo JM (1995) Molecular characterization of glyoxalase-I from a higher plant; upregulation by stress. Plant Mol Biol 29(6):1223–1233

Foyer CH, Noctor G (2005) Redox homeostasis and antioxidant signaling: a metabolic interface between stress perception and physiological responses. Plant Cell 17:1866–1875

Freeman JL, Persans MW, Nieman K, Albrecht C, Peer W, Pickering IJ, Salt DE (2004) Increased glutathione biosynthesis plays a role in nickel tolerance in Thlaspi nickel hyperaccumulators. Plant Cell 16:2176–2191

Fujita M (1985) The presence of two Cd-binding components in the roots of water hyacinth cultivated in a Cd2+-containing medium. Plant Cell Physiol 26(2):295–300

Goldsbrough PB (1998) Metal tolerance in plants: the role of phytochelatins and metallothioneins. In: Terry N, Banuelos GS (eds) Phytoremediation of trace elements. CRC Press, Boca Raton, pp 221–233

Gough LP, Shacklette HT, Case AA (1979) Element concentrations toxic to plants, animals and man. U.S. Geological Survey, Washington, DC: 1466

Gücel S, Ozturk M, Yucel E, Kadis C, Guvensen A (2009a) Studies on the trace metals in the soils and plants growing in the vicinity of Copper Mining Area—Lefke, Northern Cyprus. Fresenius Environ Bull 18(3):360–368

Gücel S, Kocbas F, Ozturk M (2009b) Metal bioaccumulation by barley in Mesaoria Plain alongside the Nicosia Famagusta Highway, Northern Cyprus. Fresenius Environ Bull 18(11):2034–2039

Guerinot ML (2000) The ZIP family of metal transporters. Biochim Biophys Acta 1465:190–198

Gupta VK, Ali I (2002) Encyclopedia of surface and colloid science. Marcel Dekker, New York, pp 136–166

Gupta VK, Ali I (2012) Environmental water: advances in treatment, remediation and recycling. Elsevier, Dordrecht

Gupta DK, Vandenhove H, Inouhe M (2013) Role of phytochelatins in heavy metal stress and detoxification mechanisms in plants. In: Gupta D, Corpas F, Palma J (eds) Heavy metal stress in plants. Springer, Berlin, pp 73–94

Hakeem KR, Sabir M, Ozturk M, Mermut A (2015) Soil remediation and plants: prospects and challenges. Elsevier, London, p 724

Hakeem KR, Sabir M, Ozturk M, Akhtar MS, Ibrahim FH (2017) Nitrate and nitrogen oxides: sources, health effects and their remediation. In: Gunther FA, de Voogt P (eds) Reviews of environmental contamination and toxicology, vol 242. Springer, Cham, pp 183–217

Hameed A, Qadri TN, Zaffar M, Siddiqi TO, Ozturk M, Altay V, Ahmad P (2017) Biochemical and nutritional responses of Abelmoschus esculentus L. exposed to mercury contamination. Fresenius Environ Bull 26(10):5814–5823

Haribabu TE, Sudha PN (2011) Effects of heavy metals copper and cadmium exposure on the antioxidants properties of the plant cleome gynandra. Ijpaes 1(2):80–87

Hasanuzzaman M, Nahar K, Hakeem KR, Ozturk M, Fujita M (2015) Arsenic toxicity in plants and possible remediation. In: Hakeem K, Sabir M, Ozturk M, Mermut A (eds) Soil remediation and plants: prospects and challenges. Elsevier, New York, pp 433–501

Hoque MA, Uraji M, Akhter Banu MN, Mori IC, Nakamura Y, Murata Y (2010) The effects of methylglyoxal on glutathione S-transferase from Nicotiana tabacum. Biosci Biotechnol Biochem 74(10):2124–2126

Horst WJ (1983) Factors responsible for genotypic manganese tolerance in cowpea (Vigna unguiculata). Plant Soil 72(2–3):213–218

Hossain MA, Hossain MZ, Fujita M (2009) Stress-induced changes of methylglyoxal level and glyoxalase I activity in pumpkin seedlings and cDNA cloning of glyoxalase I gene. Aust J Crop Sci 3(2):53–64

Hossain MA, Hasanuzzaman M, Fujita M (2010) Up-regulation of antioxidant and glyoxalase systems by exogenous glycinebetaine and proline in mung bean confer tolerance to cadmium stress. Physiol Mol Biol Plants 16(3):259–272

Hossain MA, da Silva JAT, Fujita M (2011) Glyoxalase system and reactive oxygen species detoxification system in plant abiotic stress response and tolerance: an intimate relationship. In: Shanker AK, Venkateswarlu B (eds) Abiotic stress in plants-mechanisms and adaptations. Intech-Open Access Publisher, Rijeka, pp 235–266

Hossain MA, Piyatida P, Silva JAT, Fujita M (2012) Molecular mechanism of heavy metal toxicity and tolerance in plants: central role of glutathione in detoxification of reactive oxygen species and methylglyoxal and in heavy metal chelation. J Bot 2012:1–37

Huang JW, Pellet DM, Papernik LA, Kochian LV (1996) Aluminum interactions with voltage-dependent calcium transport in plasma membrane vesicles isolated from roots of aluminum-sensitive and -resistant wheat cultivars. Plant Physiol 110(2):561–569

Ichimura K, Shinozaki K, Tena G, Sheen J, Henry Y, Champion A, Kreis M, Zhang SQ, Hirt H, Wilson C, Heberle-Bors E et al (2002) Mitogen-activated protein kinase cascades in plants: a new nomenclature. Trends Plant Sci 7:301–308

Jalmi SK, Bhagat PK, Verma D, Noryang S, Tayyeba S, Singh K, Sharma D, Sinha AK (2018) Traversing the links between heavy metal stress and plant signaling. Front Plant Sci 9:12. https://doi.org/10.3389/fpls.2018.00012

Jonak C, Okresz L, Bogre L, Hirt H (2002) Complexity, cross talk and integration of plant MAP kinase signalling. Curr Opin Plant Biol 5:415–424

Karplus PA, Daniels MJ, Herriot JR (1999) Atomic structure of ferredoxin-NADPH C reductase, prototype for a structurally novel flavoenzyme family. Science 251(4989):60–66

Kasprzak KS (1995) Possible role of oxidative damage in metal induced carcinogenesis. Cancer Investig 13:411–430

Kawachi M, Kobae Y, Mimura T, Maeshima M (2008) Deletion of a histidine-rich loop of AtMTP1, a vacuolar Zn2+/H+ antiporter of Arabidopsis thaliana, stimulates the transport activity. J Biol Chem 283:8374–8383

Khan MN, Mohammad F, Mobin M, Saqib MA (2014) Tolerance of plants to abiotic stress: a role of nitric oxide and calcium. In: Khan M, Mobin M, Mohammad F, Corpas F (eds) Nitric oxide in plants: metabolism and role in stress physiology. Springer, Cham, pp 225–242

Kisa D, Elmastaş M, Öztürk L, Kayir Ö (2016) Responses of the phenolic compounds of Zea mays under heavy metal stress. Appl Biol Chem 59(6):813–820

Kopittke PM, Asher CJ, Blamey FP, Auchterlonie GJ, Guo YN, Menzies NW (2008) Localization and chemical speciation of Pb in roots of signal grass (Brachiaria decumbens) and Rhodes grass (Chloris gayana). Environ Sci Technol 42:4595–4599

Kovtun Y, Chiu WL, Tena G, Sheen J (2000) Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants. Proc Natl Acad Sci USA 97:2940–2945

Kramer U, Cotter-Howells JD, Charnock JM, Baker AJM, Smith JAC (1996) Free histidine as a metal chelator in plants that accumulate nickel. Nature 379(6566):635–638

Krzesłowska M (2011) The cell wall in plant cell response to trace metals: polysaccharide remodeling and its role in defense strategy. Acta Physiol Plant 33(1):35–51

Lamattina L, Garcia-Mata C, Graziano M, Pagnussat G (2003) Nitric oxide: the versatility of an extensive signal molecule. Annu Rev Plant Biol 54:109–136

Lanquar V, Lelièvre F, Bolte S, Hamès C, Alcon C, Neumann D, Vansuyt G, Curie C, Schröder A, Krämer U, Barbier-Brygoo H, Thomine S (2005) Mobilization of vacuolar iron by AtNRAMP3 and AtNRAMP4 is essential for seed germination on low iron. EMBO J 24:4041–4051

Lee CW, Choi JM, Pak CH (1996) Micronutrient toxicity in seed geranium (Pelargonium x Hortorum Bailey). J Am Soc Hortic Sci 121:77–82

Lee K, Bae DW, Kim SH, Han HJ, Liu X, Park HC, Lim CO, Lee SY, Chung WS (2010) Comparative proteomic analysis of the short-term responses of rice roots and leaves to cadmium. J Plant Physiol 167(3):161–168

Levine A, Tenhaken R, Dixon R, Lamb C (1994) H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response. Cell 79(4):83–593

Li Y, Dhankher OP, Carreira L, Balish RS, Meagher RB (2005) Arsenic and mercury tolerance and cadmium sensitivity in Arabidopsis plants expressing bacterial γ-glutamylcysteine synthetase. Environ Toxicol Chem 24:1376–1386

Liu H, Zhang J, Christie P, Zhang F (2008) Influence of iron plaque on uptake and accumulation of Cd by rice (Oryza sativa L.) seedlings grown in soil. Sci Total Environ 394(2–3):361–368

Malar S, Vikram SS, Favas PJC, Perumal V (2014) Lead heavy metal toxicity induced changes on growth and antioxidative enzymes level in water hyacinths [Eichhornia crassipes (Mart.)]. Bot Stud Int J 55:54

Malar S, Sahi SV, Favas PJC, Venkatachalam P (2015) Mercury heavy-metal-induced physiochemical changes and genotoxic alterations in water hyacinths [Eichhornia crassipes (Mart.)]. Environ Sci Pollut Res 22(6):4597–4608

Manara A (2012) Plant responses to heavy metal toxicity. In: Furini A (ed) Plants and heavy metals. Springer, Dordrecht, pp 27–53

Mäser P, Thomine S, Schroeder JI, Ward JM, Hirschi K, Sze H, Talke IN, Amtmann A, Maathuis FJM et al (2001) Phylogenetic relationships within cation transporter families of Arabidopsis. Plant Physiol 126:1646–1667

Meharg AA (1994) Integrated tolerance mechanisms-constitutive and adaptive plant-response to elevated metal concentrations in the environment. Plant Cell Environ 17:989–993

Meharg AA, Macnair MR (1992) Suppression of the high affinity phosphate uptake system; a mechanism of arsenate tolerance in Holcus lanatus L. J Exp Bot 43:519–524

Michalak A (2006) Phenolic compounds and their antioxidant activity in plants growing under heavy metal stress. Pol J Environ Stud 15(4):523–530

Millar AH, Mittova V, Kiddle G, Heazlewood JL, Bartoli CG, Theodoulou FL, Foyer CH (2003) Control of ascorbate synthesis by respiration and its implications for stress responses. Plant Physiol 133:443–447

Mills RF, Krijger GC, Baccarini PJ, Hall JL, Williams LE (2003) Functional expression of AtHMA4, a P1B-type ATPase of the Zn/Co/Cd/Pb subclass. Plant J 35:164–176

Minglin L, Yuxiu Z, Tuanyao C (2005) Identification of genes up-regulated in response to Cd exposure in Brassica juncea L. Gene 363:151–158

Mittler R, Vanderauwera S, Gollery M, van Breusegem F (2004) Reactive oxygen gene network of plants. Trends Plant Sci 9:490–498

Mullineaux P, Rausch T (2005) Glutathione, photosynthesis and the redox regulation of stress-responsive gene expression. Photosynth Res 86:459–474

Nagajyoti PC, Lee KD, Sreekanth TVM (2010) Heavy metals, occurrence and toxicity for plants: a review. Environ Chem Lett 8(3):199–216

National Research Council [US—Committee on Medical and Biological Effects of Environmental Pollutants] (1997) Arsenic: medical and biologic effects of environmental pollutants. National Academic Press, Washington

Navari-Izzo F (1998) Thylakoid-bound and stromal antioxidative enzymes in wheat treated with excess copper. Physiol Plant 104(4):630–638

Neelima P, Reddy KJ (2002) Interaction of copper and cadmium with seedlings growth and biochemical responses in Solanum melongena. Environ Pollut Technol 1:285–290

Neumann D, zur Nieden U (2001) Silicon and heavy metal tolerance in higher plants. Phytochemistry 56:685–692

Nevo Y, Nelson N (2006) The NRAMP family of metal-ion transporters. Biochim Biophys Acta 1763:609–620

Nocito FF, Lancilli C, Crema B, Fourcroy P, Davidian JC, Sacchi GA (2006) Heavy metal stress and sulfate uptake in maize roots. Plant Physiol 141:1138–1148

Opdenakker K, Remans T, Vangronsveld J, Cuypers A (2013) Mitogen-activated protein (MAP) kinases in plant metal stress: regulation and responses in comparison to other biotic and abiotic stresses. Int J Mol Sci 13(6):7828–7853

Ortiz DF, Ruscitti T, McCue KF, Ow DW (1995) Transport of metal-binding peptides by HMT1, a fission yeast ABC-type vacuolar membrane protein. J Biol Chem 270:4721–4728

Ouyang H, Vogel HJ (1998) Metal ion binding to calmodulin: NMR and fluorescence studies. Biometals 11(3):213–222

Ovečka M, Takáč T (2014) Managing heavy metal toxicity stress in plants: biological and biotechnological tools. Biotechnol Adv 32(1):73–86

Ozturk M (ed) (1989) Plants and pollutants in developed and developing countries. Ege University Press, Izmir, p 759

Ozturk M, Turkan I (1993) Heavy metal accumulation by plants growing alongside the motor roads: a case study from Turkey. In: Markert B (ed) Plants as biomonitors: indicators for heavy metals in the terrestrial environment. VCH Publishers, Berlin, pp 515–522

Ozturk M, Yucel E, Gucel S, Sakcali S, Aksoy A (2008) Plants as biomonitors of trace elements pollution in soil. In: Prasad MNV (ed) Trace elements: environmental contamination, nutritional benefits and health implications. Wiley, New York, pp 723–744

Ozturk M, Memon AR, Gucel S, Sakcali MS (2012) Brassicas in Turkey and their possible role in the phytoremediation of degraded habitats. In: Anjum NA et al (eds) The plant family Brassicaceae: contribution towards phytoremediation, vol 21. Environmental Pollution Book Series. Springer, New York, pp 265–288

Ozturk M, Sakcali S, Celik A (2013a) A Biomonitor of heavy metal on ruderal habitats in Turkey—Diplotaxis tenuifolia (L.) DC. Sains Malaysiana 42(10):1371–1376

Ozturk M, Gucel S, Sakcali S, Baslar S (2013b) Nitrate and edible plants in the Mediterranean Region of Turkey: an overview. In: Umar S et al (eds) Nitrate in leafy vegetables-toxicity and safety measures. IK Intern Publ House Pvt Ltd, New Delhi, pp 17–51

Ozturk M, Ashraf M, Aksoy A, Ahmad MSA (eds) (2015a) Phytoremediation for green energy. Springer, New York

Ozturk M, Ashraf M, Aksoy A, Ahmad MSA (eds) (2015b) Plants, pollutants & remediation. Springer, New York

Ozturk M, Altay V, Karahan F (2017) Studies on trace elements in Glycyrrhiza taxa distributed in Hatay-Turkey. Int J Plant Environ 3(2):01–07

Pellet DM, Grunes DL, Kochian LV (1995) Organic acid exudation as an aluminum-tolerance mechanism in maize (Zea mays L.). Planta 196(4):788–795

Pinto AP, Simoes I, Mota AM (2008) Cadmium impact on root exudates of sorghum and maize plants: a speciation study. J Plant Nutr 31(10):1746–1755

Pitzschke A, Forzani C, Hirt H (2006) Reactive oxygen species signaling in plants. Antioxid Redox Signal 8:1757–1764

Pitzschke A, Djamei A, Bitton F, Hirt H (2009) A major role of the MEKK1-MKK1/2-MPK4 pathway in ROS signalling. Mol Plant 2:120–137

Polle A, Schutzendubel A (2004) Heavy metal signaling in plants: linking cellular and organismic responses. In: Hirt H, Shinozaki K (eds) Plant responses to abiotic stress, vol 4. Topics in Current Genetics. Springer, Berlin, pp 187–215

Puig S, Thiele DJ (2002) Molecular mechanisms of copper uptake and distribution. Curr Opin Chem Biol 6:171–180

Queval G, Foyer C (2012) Redox regulation of photosynthetic gene expression. Philos Trans R Soc B 367:3475–3485

Rao KP, Vani G, Kumar K, Wankhede DP, Misra M, Gupta M, Sinha AK (2011) Arsenic stress activates MAP kinase in rice roots and leaves. Arch Biochem Biophys 506:73–82

Rascio N, Navari-Izzo F (2011) Heavy metal hyperaccumulating plants: how and why do they do it? And what makes them so interesting? Plant Sci 180(2):169–181

Ray S, Dutta S, Halder J, Ray M (1994) Inhibition of electron flow through complex I of the mitochondrial respiratory chain of Ehrlich ascites carcinoma cells by methylglyoxal. Biochem J 303(1):69–72

Renard CMGC, Jarvis MC (1999) Acetylation and methylation of homogalacturonans. 2: effect on ion-binding properties and conformations. Carbohydr Polym 39:209–216

Rentel MC, Lecourieux D, Ouaked F, Usher SL, Petersen L, Okamoto H, Knight H, Peck SC, Grierson CS, Hirt H, Knight MR (2004) OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis. Nature 427:858–861

Richard JP (1993) Mechanism for the formation of methylglyoxal from triosephosphates. Biochem Soc Trans 21(2):549–553

Rivetta A, Negrini N, Cocucci M (1997) Involvement of Ca2+–calmodulin in Cd 2+ toxicity during the early phases of radish (Raphanus sativus L.) seed germination. Plant Cell Environ 20(5):600–608

Rizwan M, Ali S, Abbas T, Adrees M, Zia-ur-Rehman M, Ibrahim M, Abbas F, Qayyum MF, Nawaz R (2018) Residual effects of biochar on growth, photosynthesis and cadmium uptake in rice (Oryza sativa L.) under Cd stress with different water conditions. J Environ Manag 206:676–683

Roelofs D, Aarts MGM, Schat H, van Straalen NM (2008) Functional ecological genomics to demonstrate general and specific responses to abiotic stress. Funct Ecol 22:8–18

Romero-Puertas MC, Palma JM, Gomez M, Del Rıo LA, Sandalio LM (2002) Cadmium causes the oxidative modification of proteins in pea plants. Plant Cell Environ 25(5):677–686

Sabir M, Waraich EA, Hakeem KR, Ozturk M, Ahmad HR, Shahid M (2015) Phytoremediation: mechanisms and adaptations. In: Hakeem K, Sabir M, Ozturk M, Mermut A (eds) Soil remediation and plants: prospects and challenges. Elsevier, New York, pp 85–105

Saito R, Yamamoto H, Makino A, Sugimoto T, Miyake C (2011) Methylglyoxal functions as Hill oxidant and stimulates the photoreduction of O(2) at photosystem I: a symptom of plant diabetes. Plant Cell Environ 34(9):1454–1464

Salt DE, Blaylock M, Kumar NPBA, Dushenkov V, Ensley D, Chet I, Raskin I (1995) Phytoremediation: a novel strategy for the removal of toxic metals from the environment using plants. Biotechnology 13:468–474

Sanita Di Toppi L, Gabbrielli R (1999) Response to cadmium in higher plants. Environ Exp Bot 41(2):105–130

Saxena I, Shekhawat GS (2013) Nitric oxide (NO) in alleviation of heavy metal induced phytotoxicity and its role in protein nitration. Nitric Oxide 32:13–20

Schaaf G, Ludewig U, Erenoglu BE, Mori S, Kitahara T, von Wirén N (2004) ZmYS1 functions as a proton-coupled symporter for phyto siderophore- and nicotianamine-chelated metals. J Biol Chem 279:9091–9096

Schaaf G, Schikora A, Häberle J, Vert G, Ludewig U, Briat JF, Curie C, von Wirén N (2005) A putative function for the Arabidopsis Fe-Phyto siderophore transporter homolog AtYSL2 in Fe and Zn homeostasis. Plant Cell Physiol 46:762–774

Schmfger MEV (2001) Phytochelatins: complexation of metals and metalloids, studies on the phytochelatin synthase. Ph.D. Thesis, Munich University of Technology (TUM), Munich

Shahid M, Khalid S, Abbas G, Shahid N, Nadeem M, Sabir M, Aslam M, Dumat C (2015) Heavy metal stress and crop productivity. In: Hakeem K et al (eds) Crop production and global environmental issues. Springer, Cham

Shahzad B, Tanveer M, Che Z, Rehman A, Cheema SA, Sharma A, Song H, Rehman S, Zhaorong D (2018) Role of 24-epibrassinolide (EBL) in mediating heavy metal and pesticide induced oxidative stress in plants: a review. Ecotoxicol Environ Saf 147:935–944

Shanker AK, Djanaguiraman M, Pathmanabhan G, Sudhagar R, Avudainayagam S (2003) Uptake and phytoaccumulation of chromium by selected tree species. In: Proceedings of the international conference on water and environment held in Bhopal, India

Shao HB, Chu LY, Lu ZH, Kang CM (2008) Primary antioxidant free radical scavenging and redox signaling pathways in higher plant cells. Int J Biol Sci 4:8–14

Shao HB, Chu LY, Ni FT, Guo DG, Li H, Li WX (2010) Perspective on phytoremediation for improving heavy metal contaminated soils. In: Ashraf M, Ozturk M, Ahmad M (eds) Plant adaptation and phytoremediation, vol 2. Springer, Dordrecht, pp 227–244

Sharma S, Ali I (2011) Adsorption of Rhodamine B dye from aqueous solution onto acid activated mango (Magnifera indica) leaf powder: equilibrium, kinetic and thermodynamic studies. J Toxicol Environ Health Sci 3(10):286–297

Sharma P, Dubey RS (2005) Lead toxicity in plants. Braz J Plant Physiol 17(1):35–52

Sharma P, Kumar A, Bhardwaj R (2016a) Plant steroidal hormone epibrassinolide regulate—heavy metal stress tolerance in Oryza sativa L. by modulating antioxidant defense expression. Environ Exp Bot 122:1–9

Sharma SS, Dietz K-J, Mimura T (2016b) Vacuolar compartmentalization as indispensable component of heavy metal detoxification in plants. Plant Cell Environ 39:1112–1126. https://doi.org/10.1111/pce.12706

Shi Q, Ding F, Wang X, Wei M (2007) Exogenous nitric oxide protect cucumber roots against oxidative stress induced by salt stress. Plant Physiol Biochem 45(8):542–550

Siddiqui MH, Al-Whaibi MH, Basalah MO (2011) Role of nitric oxide in tolerance of plants to abiotic stress. Protoplasma 248(3):447–455

Singla-Pareek SL, Yadav SK, Pareek A, Reddy MK, Sopory SK (2006) Transgenic tobacco overexpressing glyoxalase pathway enzymes grow and set viable seeds in zinc-spiked soils. Plant Physiol 140(2):613–623

Snedden WA, Fromm H (2001) Calmodulin as a versatile calcium signal transducer in plants. New Phytol 151:35–66

Sobrino-Plata J, Ortega-Villasante C, Flores-Cáceres ML, Escobar C, Del Campo FF, Hernández LE (2009) Differential alterations of antioxidant defenses as bioindicators of mercury and cadmium toxicity in alfalfa. Chemosphere 77:946–954

Sytar O, Kumar A, Latowski D, Kuczynska P, Strzałka K, Prasad MNV (2013) Heavy metal-induced oxidative damage, defense reactions, and detoxification mechanisms in plants. Acta Physiol Plant 35(4):985–999

Tangahu BV, Sheikh Abdullah SR, Basri H, Idris M, Anuar N, Mukhlisin M (2011) A review on heavy metals (As, Pb, and Hg) uptake by plants through phytoremediation. Int J Chem Eng 2011:1–31

Tauqeer HM, Ali S, Rizwan M, Ali Q, Saeed R, Iftikhar U, Ahmad R, Farid M, Abbasi GH (2016) Phytoremediation of heavy metals by Alternanthera bettzickiana: growth and physiological response. Ecotoxicol Environ Saf 126:138–146

Tena G, Asai T, Chiu WL, Sheen J (2001) Plant mitogen activated protein kinase signaling cascades. Curr Opin Plant Biol 4:392–400

Thao NP, Khan MIR, Thu NBA, Hoang XLT, Asgher M, Khan NA, Tran L-SP (2015) Role of ethylene and its cross talk with other signaling molecules in plant responses to heavy metal stress. Plant Physiol 169(1):73–84. https://doi.org/10.1104/pp.15.00663

Thapa G, Sadhukhan A, Panda SK, Sahoo L (2012) Molecular mechanistic model of plant heavy metal tolerance. Biometals 25(3):489–505

Thomine S, Wang R, Ward JM, Crawford NM, Schroeder JI (2000) Cadmium and iron transport by members of a plant metal transporters family in Arabidopsis with homology to NRAMP genes. Proc Natl Acad Sci USA 97:4991–4996

Thomine S, Lelievre F, Debarbieux E, Schroeder JI, Barbier-Brygoo H (2003) AtNRAMP3, a multi specific vacuolar metal transporter involved in plant responses to iron deficiency. Plant J 34:685–695

Thornalley PJ (1990) The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life. Biochem J 269(1):1

Todeschini V, Lingua G, D’Agostino G, Carniato F, Roccotiello E, Berta G (2011) Effects of high zinc concentration on poplar leaves: a morphological and biochemical study. Environ Exp Bot 71(1):50–56

van der Zaal BJ, Neuteboom LW, Pinas JE, Chardonnens AN, Schat H, Verkleij JAC, Hooykaas PJJ (1999) Overexpression of a novel Arabidopsis gene related to putative zinc-transporter genes from animals can lead to enhanced zinc resistance and accumulation. Plant Physiol 119:1047–1055

Vatansever R, Ozyigit II, Filiz E (2017) Essential and beneficial trace elements in plants, and their transport in roots: a review. Appl Biochem Biotechnol 181(1):464–482

Verret F, Gravot A, Auroy P, Leonhardt N, David P, Nussaume L, Vavasseur A, Richaud P (2004) Overexpression of AtHMA4 enhances root-to-shoot translocation of zinc and cadmium and plant metal tolerance. FEBS Lett 576:306–312

Williams LE, Pittman JK, Hall JL (2000) Emerging mechanisms for heavy metal transport in plants. Biochim Biophys Acta 77803:1–23

Winkel-Shirley B (2002) Biosynthesis of flavonoids and effects of stress. Curr Opin Plant Biol 5:218

Wu L, Juurlink BHJ (2002) Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells. Hypertension 39(3):809–814

Xiang C, Werner BL, Christensen EM, Oliver DJ (2001) The biological functions of glutathione revisited in Arabidopsis transgenic plants with altered glutathione levels. Plant Physiol 126:564–574

Xiumin C, Yikai Z, Xiuling C, Hong J, Xiaobin W (2009) Effects of exogenous nitric oxide protects tomato plants under copper stress. In: Proceedings of the 3rd international conference on bioinformatics and biomedical engineering (ICBBE’09), pp 1–7, Beijing, China

Yadav SK (2010) Heavy metals toxicity in plants: an overview on the role of glutathione and phytochelatins in heavy metal stress tolerance of plants. S Afr J Bot 76(2):167–179

Yadav SK, Singla-Pareek SL, Ray M, Reddy MK, Sopory SK (2005a) Methylglyoxal levels in plants under salinity stress are dependent on glyoxalase I and glutathione. Biochem Biophys Res Commun 337(1):61–67

Yadav SK, Singla-Pareek SL, Reddy MK, Sopory SK (2005b) Methylglyoxal detoxification by glyoxalase system: a survival strategy during environmental stresses. Physiol Mol Biol Plants 11(1):1–11

Yang XE, Jin XF, Feng Y, Islam E (2005) Molecular mechanisms and genetic basis of heavy metal tolerance/hyperaccumulation in plants. J Integr Plant Biol 47(9):1025–1035

Yilmaz R, Sakcali S, Yarci C, Aksoy A, Ozturk M (2006) Use of Aesculus hippocastanum L. as a biomonitor of heavy metal pollution. Pak J Bot 38(5):1519–1527

Yuan HM, Liu WC, Jin Y, Lu YT (2013) Role of ROS and auxin in plant response to metal-mediated stress. Plant Signal Behav 8(7):e24671

Zagorchev L, Seal CE, Kranner I, Odjakova M (2013) A central role for thiols in plant tolerance to abiotic stress. Int J Mol Sci 14(4):7405–7432

Zeid IM (2001) Responses of Phaseolus vulgaris to chromium and cobalt treatments. Biol Plant 44:111–115

Zhao L, Sun YL, Cui SX (2011) Cd-induced changes in leaf proteome of the hyperaccumulator plant Phytolacca americana. Chemosphere 85(1):56–66

Zhen Y, Qi JL, Wang SS, Jing S, Xu GH, Zhang MS, Miao L, Peng XX, Tian D, Yang YH (2007) Comparative proteome analysis of differentially expressed proteins induced by Al toxicity in soybean. Physiol Plant 131(4):542–554

Zheng C, Jiang D, Liu F, Dai T, Liu W, Jing Q, Cao W (2009) Exogenous nitric oxide improves seed germination in wheat against mitochondrial oxidative damage induced by high salinity. Environ Exp Bot 67(1):222–227