Heat shock protein 70 down-regulates the production of toll-like receptor-induced pro-inflammatory cytokines by a heat shock factor-1/constitutive heat shock element-binding factor-dependent mechanism

Eduardo Ferat‐Osorio1, Aldair Sánchez-Anaya2, Mireille Gutiérrez-Mendoza1, Ilka Boscó-Gárate1, Isabel Wong‐Baeza3,1, Rodolfo Pastelin‐Palacios4, Gustavo Pedraza‐Alva5, Laura C. Bonifaz1, Pedro Cortés‐Reynosa6, Eduardo Perez‐Salazar6, Lourdes Arriaga‐Pizano1, Constantino López‐Macías1, Yvonne Rosenstein7, Armando Isibasi1
1Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México D.F., México
2Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Av. Cuauhtémoc 330, Col. Doctores, México D.F. CP 06020, México.
3Departamento de Inmunología, Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, México D.F., México
4Facultad de Química, Universidad Nacional Autónoma de México (UNAM), México, D.F., México
5Departamento de Medicina Molecular y Bioprocesos. Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México
6Departamento de Biología Celular, (CINVESTAV) Instituto Politécnico Nacional, Centro de Investigación y Estudios Avanzados, México D.F., México
7Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Col. Chamilpa, Cuernavaca Mor, México

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