Hair grows hair: Dual-effective hair regrowth through a hair enhanced dissolvable microneedle patch cooperated with the pure yellow light irradiation

Pratt, 2017, Alopecia areata, Nat. Rev. Dis. Primers, 3, 17011, 10.1038/nrdp.2017.11 Lee, 2019, Epidemiology of alopecia areata, totalis, universalis, and ophiasis: A systematic review and meta-analysis, J. Invest. Dermatol., 139 Olsen, 2005, Evaluation and treatment of male and female pattern hair loss, J. Am. Acad. Dermatol., 52, 301, 10.1016/j.jaad.2004.04.008 Salim, 2020, Controlled drug delivery for alopecia: A review, J. Control. Release, 325, 84, 10.1016/j.jconrel.2020.06.019 Mir-Palomo, 2020, Co-loading of finasteride and baicalin in phospholipid vesicles tailored for the treatment of hair disorders, Nanoscale, 12, 16143, 10.1039/D0NR03357J Hooper, 2020, Platelet-rich plasma has a place in the treatment of androgenetic alopecia, J. Am. Acad. Dermatol. Lee, 2018, Trichogenic Photostimulation Using Monolithic Flexible Vertical AlGaInP Light- Emitting Diodes, ACS Nano, 12, 9587, 10.1021/acsnano.8b05568 Chu, 2019, Mechanical stretch induces hair regeneration through the alternative activation of macrophages, Nat. Commun., 10, 1524, 10.1038/s41467-019-09402-8 Yao, 2019, Self-Activated Electrical Stimulation for Effective Hair Regeneration via a Wearable Omnidirectional Pulse Generator, ACS Nano, 13, 12345, 10.1021/acsnano.9b03912 Rahmani, 2014, Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type, Dev. Cell, 31, 543, 10.1016/j.devcel.2014.10.022 Al-Refu, 2012, Stem cells and alopecia: a review of pathogenesis, Br. J. Dermatol., 167, 479, 10.1111/j.1365-2133.2012.11018.x Yang, 2019, A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth, ACS Nano, 13, 4354, 10.1021/acsnano.8b09573 Hu, 2020, Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling, Sci. Adv., 6, eaba1685, 10.1126/sciadv.aba1685 Ha, 2020, Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration, Cells, 9, 1157, 10.3390/cells9051157 Rajendran, 2017, Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice, Sci. Rep., 7, 15560, 10.1038/s41598-017-15505-3 Du, 2019, Hyaluronic Acid-Based Dissolving Microneedle Patch Loaded with Methotrexate for Improved Treatment of Psoriasis, ACS Appl. Mater. Interfaces, 11, 43588, 10.1021/acsami.9b15668 Zhang, 2017, Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment, ACS Nano, 11, 9223, 10.1021/acsnano.7b04348 Leichner, 2019, Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature, Adv. Drug. Deliv. Rev., 151, 191, 10.1016/j.addr.2019.04.007 Leichner, 2019, Reactive keratin derivatives: A promising strategy for covalent binding to hair, J. Colloid Interface Sci., 534, 533, 10.1016/j.jcis.2018.09.062 Darwin, 2018, Low-level laser therapy for the treatment of androgenic alopecia: a review, Lasers Med. Sci., 33, 425, 10.1007/s10103-017-2385-5 Guo, 2020, Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia, Lasers Med. Sci. Galadari, 2020, Low-level laser therapy and narrative review of other treatment modalities in androgenetic alopecia, Lasers Med. Sci., 35, 1239, 10.1007/s10103-020-02994-4 Lin, 2019, Several biological benefits of the low color temperature light-emitting diodes based normal indoor lighting source, Sci. Rep., 9, 7560, 10.1038/s41598-019-43864-6 Chao, 2018, Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses, Nature Biomedical Engineering, 2, 611, 10.1038/s41551-018-0262-6 Machado, 2021, Novel rivaroxaban-loaded poly(lactic-co-glycolic acid)/poloxamer nanoparticles: preparation, physicochemical characterization, in vitro evaluation of time-dependent anticoagulant activity and toxicological profile, Nanotechnology, 32, 10.1088/1361-6528/abd0b5 Zheng, 2018, Hierarchical Micro-/Nanostructures from Human Hair for Biomedical Applications, Adv. Mater., 30, 10.1002/adma.201800836 Peng, 2020, Black phosphorus modified soluble microneedle patch for painless, effective and accurate body slimming, Applied Materials Today, 19, 10.1016/j.apmt.2020.100577 Chen, 2018, Additive Manufacturing of Honeybee-Inspired Microneedle for Easy Skin Insertion and Difficult Removal, ACS Appl. Mater. Interfaces, 10, 29338, 10.1021/acsami.8b09563 Kageyama, 2018, Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine, Biomaterials, 154, 291, 10.1016/j.biomaterials.2017.10.056 Mendes, 2020, Effects of the Association between Photobiomodulation and Hyaluronic Acid Linked Gold Nanoparticles in Wound Healing, ACS Biomaterials Science & Engineering, 6, 5132, 10.1021/acsbiomaterials.0c00294 Chen, 2020, Sustained release of dermal papilla-derived extracellular vesicles from injectable microgel promotes hair growth, Theranostics, 10, 1454, 10.7150/thno.39566 Kim, 2019, Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy, Nat. Commun., 10, 3694, 10.1038/s41467-019-11665-0