HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells

Procino, 2013, The HOX genes network in metabolic diseases, Cell Biol. Int., 37, 1145 Ali, 2013, Adipocyte and adipogenesis, Eur. J. Cell Biol., 92, 229, 10.1016/j.ejcb.2013.06.001 Huang, 2009, BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage, Proc. Natl. Acad. Sci. U. S. A., 106, 12670, 10.1073/pnas.0906266106 Grafe, 2017, TGF-β family signaling in mesenchymal differentiation, Cold Spring Harb. Perspect. Biol., a022202 Cristancho, 2011, Forming functional fat: a growing understanding of adipocyte differentiation, Nat. Rev. Mol. Cell Biol., 12, 722, 10.1038/nrm3198 Hilton, 2015, Role of developmental transcription factors in white, brown and beige adipose tissues, Biochim. Biophys. Acta, 1851, 686, 10.1016/j.bbalip.2015.02.003 Rosen, 2000, Molecular regulation of adipogenesis, Annu. Rev. Cell Dev. Biol., 16, 145, 10.1146/annurev.cellbio.16.1.145 Guilak, 2010, Clonal analysis of the differentiation potential of human adipose-derived adult stem cells, J. Cell. Physiol., 206, 229, 10.1002/jcp.20463 Nadri, 2007, An efficient method for isolation of murine bone marrow mesenchymal stem cells, Int. J. Dev. Biol., 51, 723, 10.1387/ijdb.072352ns Li, 2013, Evaluation of isolation methods and culture conditions for rat bone marrow mesenchymal stem cells, Cytotechnology, 65, 323, 10.1007/s10616-012-9497-3 Kastrinaki, 2008, Isolation of human bone marrow mesenchymal stem cells using different membrane markers: comparison of colony/cloning efficiency, differentiation potential, and molecular profile, Tissue Eng. C Methods, 14, 333, 10.1089/ten.tec.2008.0173 Bosnakovski, 2005, Isolation and multilineage differentiation of bovine bone marrow mesenchymal stem cells, Cell Tissue Res., 319, 243, 10.1007/s00441-004-1012-5 Bosch, 2006, Isolation, characterization, gene modification, and nuclear reprogramming of porcine mesenchymal stem cells, Biol. Reprod., 74, 46, 10.1095/biolreprod.105.045138 Reich, 2012, Isolation, culture and chondrogenic differentiation of canine adipose tissue- and bone marrow-derived mesenchymal stem cells–a comparative study, Vet. Res. Commun., 36, 139, 10.1007/s11259-012-9523-0 Liu, 2015, Erratum to: isolation, culture, and induced multiple differentiation of Mongolian sheep bone marrow-derived mesenchymal stem cells, In Vitro Cell. Dev. Biol. Anim., 51, 539, 10.1007/s11626-014-9794-6 Czernik, 2012, Differentiation potential and GFP labeling of sheep bone marrow-derived mesenchymal stem cells, J. Cell. Biochem., 114, 134, 10.1002/jcb.24310 Rentsch, 2010, Ovine bone marrow mesenchymal stem cells: isolation and characterization of the cells and their osteogenic differentiation potential on embroidered and surface-modified polycaprolactone-co-lactide scaffolds, In Vitro Cell. Dev. Anim., 46, 624, 10.1007/s11626-010-9316-0 Krampera, 2003, Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide, Blood, 101, 3722, 10.1182/blood-2002-07-2104 Martin, 1990, Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs, Calcif. Tissue Int., 46, 189, 10.1007/BF02555043 Park, 1999, Interconversion potential of cloned human marrow adipocytes in vitro, Bone, 24, 549, 10.1016/S8756-3282(99)00084-8 Rodeheffer, 2008, Identification of white adipocyte progenitor cells in vivo, Cell, 135, 240, 10.1016/j.cell.2008.09.036 Tang, 2008, White fat progenitor cells reside in the adipose vasculature, Science, 322, 583, 10.1126/science.1156232 Pearson, 2005, Modulating Hox gene functions during animal body patterning, Nat. Rev. Genet., 6, 893, 10.1038/nrg1726 Abate-Shen, 2002, Deregulated homeobox gene expression in cancer: cause or consequence?, Nat. Rev. Cancer, 2, 777, 10.1038/nrc907 Duboule, 2007, The rise and fall of Hox gene clusters, Development, 134, 2549, 10.1242/dev.001065 Gesta, 2006, Evidence for a role of developmental genes in the origin of obesity and body fat distribution, Proc. Natl. Acad. Sci. U. S. A., 103, 6676, 10.1073/pnas.0601752103 Yamamoto, 2012, Adipose depots possess unique developmental gene signatures, Obesity, 18, 872, 10.1038/oby.2009.512 Yoneyama, 2014, Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations, Hum. Mol. Genet., 23, 2498, 10.1093/hmg/ddt626 Heid, 2010, Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution, Nat. Genet., 42, 949, 10.1038/ng.685 Vohl, 2012, A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men*, Obesity, 12, 1217, 10.1038/oby.2004.153 Atzmon, 2002, Differential gene expression between visceral and subcutaneous fat depots, Horm. Metab. Res., 34, 622, 10.1055/s-2002-38250 Von Eyben, 2010, Comparison of gene expression in intra-abdominal and subcutaneous fat: a study of men with morbid obesity and nonobese men using microarray and proteomics, Ann. N. Y. Acad. Sci., 1030, 508 Dankel, 2010, Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss, PLoS One, 5, 10.1371/journal.pone.0011033 Bradfield, 2012, A genome-wide association meta-analysis identifies new childhood obesity loci, Nat. Genet., 44, 526, 10.1038/ng.2247 Cantile, 2010, HOX gene network is involved in the transcriptional regulation of in vivo human adipogenesis, J. Cell. Physiol., 194, 225, 10.1002/jcp.10210 Mori, 2012, Essential role for miR-196a in brown adipogenesis of white fat progenitor cells, PLoS Biol., 10, 10.1371/journal.pbio.1001314 Carlson, 2001, Expression of Hoxb13 and Hoxc10 in developing and regenerating Axolotl limbs and tails, Dev. Biol., 229, 396, 10.1006/dbio.2000.0104 Hostikka, 2009, Axial and appendicular skeletal transformations, ligament alterations, and motor neuron loss in Hoxc10 mutants, Int. J. Biol. Sci., 5, 397, 10.7150/ijbs.5.397 Tang, 2017, HOXC10 promotes the metastasis of human lung adenocarcinoma and indicates poor survival outcome, Front. Physiol., 8, 557, 10.3389/fphys.2017.00557 Yao, 2018, HOXC10 promotes gastric cancer cell invasion and migration via regulation of the NF-κB pathway, Biochem. Biophys. Res. Commun., 501, 628, 10.1016/j.bbrc.2018.05.019 Pathiraja, 2014, Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer, Sci. Transl. Med., 6, 10.1126/scitranslmed.3008326 Zhai, 2007, Gene expression analysis of Preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion, Cancer Res., 67, 10163, 10.1158/0008-5472.CAN-07-2056 Li, 2018, HOXC10 promotes proliferation and invasion and induces immunosuppressive gene expression in glioma, FEBS J., 285, 2278, 10.1111/febs.14476 Brune, 2016, Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits, Obesity, 24, 51, 10.1002/oby.21317 Baskin, 2018, Regulation of human adipose tissue activation, gallbladder size, and bile acid metabolism by a β3-adrenergic receptor agonist, Diabetes, 67, db180462, 10.2337/db18-0462 Lim, 2016, Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis, Mol. Metab., 5, 1033, 10.1016/j.molmet.2016.08.006 Ng, 2017, HOXC10 suppresses browning of white adipose tissues, Exp. Mol. Med., 49, e292, 10.1038/emm.2016.144 Ferrannini, 2016, Genetic backgrounds determine brown remodeling of white fat in rodents, Mol. Metab., 5, 948, 10.1016/j.molmet.2016.08.013 Hu, 2017, Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway, OncoTargets Ther., 10, 4379, 10.2147/OTT.S143518 Zhou, 2015, Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via endoplasmic reticulum stress, Cancer Sci., 105, 1279, 10.1111/cas.12494 Guo, 2017, HOXC10 up-regulation promotes gastric cancer cell proliferation and metastasis through MAPK pathway, Chin. J. Canc. Res., 29 Xie, 2018, Homeobox C10 knockdown suppresses cell proliferation and promotes cell apoptosis in osteosarcoma cells through regulating caspase 3, OncoTargets Ther., 11, 473, 10.2147/OTT.S143440 Guan, 2019, Overexpression of HOXC10 promotes glioblastoma cell progression to a poor prognosis via the PI3K/AKT signalling pathway, J. Drug Target., 27, 60, 10.1080/1061186X.2018.1473408 Chen, 2013, An update on the regulation of adipogenesis, Drug Discov. Today Dis. Mech., 10, e15, 10.1016/j.ddmec.2013.04.002 Chen, 2008, Variations in DNA elucidate molecular networks that cause disease, Nature, 452, 429, 10.1038/nature06757 Tian, 2014, The effects of miR-467b on lipoprotein lipase (LPL) expression, pro-inflammatory cytokine, lipid levels and atherosclerotic lesions in apolipoprotein E knockout mice, Biochem. Biophys. Res. Commun., 443, 428, 10.1016/j.bbrc.2013.11.109 He, 2014, MicroRNA-590 attenuates lipid accumulation and pro-inflammatory cytokine secretion by targeting lipoprotein lipase gene in human THP-1 macrophages, Biochimie, 106, 81, 10.1016/j.biochi.2014.08.003 Karbiener, 2009, microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma, Biochem. Biophys. Res. Commun., 390, 247, 10.1016/j.bbrc.2009.09.098 Zhang, 2019, MicroRNA-224 impairs adipogenic differentiation of bovine preadipocytes by targeting LPL, Mol. Cell. Probes, 44, 29, 10.1016/j.mcp.2019.01.005 Wang, 2019, Effects of dietary rumen-protected betaine supplementation on performance of postpartum dairy cows and immunity of newborn calves, Animals (Basel), 9, 167, 10.3390/ani9040167 Wood, 1999, Manipulating meat quality and composition, Proc. Nutr. Soc., 58, 363, 10.1017/S0029665199000488 1988 Ding, 2012, A novel single nucleotide polymorphism in exon 7 of LPL gene and its association with carcass traits and visceral fat deposition in yak (Bos grunniens) steers, Mol. Biol. Rep., 39, 669, 10.1007/s11033-011-0784-4 Oh, 2013, Identification of novel single nucleotide polymorphisms (SNPs) of the lipoprotein lipase (LPL) gene associated with fatty acid composition in Korean cattle, Mol. Biol. Rep., 40, 3155, 10.1007/s11033-012-2389-y