HIF-1α induced NID1 expression promotes pulmonary metastases via the PI3K-AKT pathway in salivary gland adenoid cystic carcinoma

Luna-Ortiz, 2009, Adenoid cystic carcinoma of the tongue–clinicopathological study and survival analysis, Head Neck Oncol, 1, 10.1186/1758-3284-1-15 Lin, 2021, Dynamic changes in pre- and postoperative levels of inflammatory markers and their effects on the prognosis of patients with gastric cancer, J Gastrointest Surg, 25, 387, 10.1007/s11605-020-04523-8 Oplatek, 2010, Patterns of recurrence and survival of head and neck adenoid cystic carcinoma after definitive resection, Laryngoscope, 120, 65, 10.1002/lary.20684 Conley, 1974, Adenoid cystic carcinoma in the head and neck (cylindroma), Arch Otolaryngol, 100, 81, 10.1001/archotol.1974.00780040087001 Khan, 2001, Adenoid cystic carcinoma: a retrospective clinical review, Int J Cancer, 96, 149, 10.1002/ijc.1013 Rh, 1997, Distant metastasis in adenoid cystic carcinoma of salivary origin, Am J Surg, 174, 458 Fordice, 1999, Adenoid cystic carcinoma of the head and neck: predictors of morbidity and mortality, Arch Otolaryngol Head Neck Surg, 125, 149, 10.1001/archotol.125.2.149 van der Wal, 2002, Distant metastases of adenoid cystic carcinoma of the salivary glands and the value of diagnostic examinations during follow-up, Head Neck, 24, 779, 10.1002/hed.10126 Coca-Pelaz, 2015, Adenoid cystic carcinoma of the head and neck–an update, Oral Oncol, 51, 652, 10.1016/j.oraloncology.2015.04.005 Bobbio, 2008, Lung metastasis resection of adenoid cystic carcinoma of salivary glands, Eur J Cardiothorac Surg, 33, 790, 10.1016/j.ejcts.2007.12.057 Cheng, 2012, Clinical significance of decreased nidogen-2 expression in the tumor tissue and serum of patients with hepatocellular carcinoma, J Surg Oncol, 105, 71, 10.1002/jso.22047 Pan, 2013, Phase and size controllable synthesis of NaYbF4 nanocrystals in oleic acid/ionic liquid two-phase system for targeted fluorescent imaging of gastric cancer, Theranostics, 3, 210, 10.7150/thno.5298 Hasengaowa, 2005, Loss of basement membrane heparan sulfate expression is associated with tumor progression in endometrial cancer, Eur J Gynaecol Oncol, 26, 403 Rowe, 2009, Navigating ECM barriers at the invasive front: the cancer cell-stroma interface, Annu Rev Cell Dev Biol, 25, 567, 10.1146/annurev.cellbio.24.110707.175315 Amenta, 2003, Loss of types XV and XIX collagen precedes basement membrane invasion in ductal carcinoma of the female breast, J Pathol, 199, 298, 10.1002/path.1303 Aumailley, 1993, Nidogen mediates the formation of ternary complexes of basement membrane components, Kidney Int, 43, 7, 10.1038/ki.1993.3 Li, 2015, Nidogen-1: a candidate biomarker for ovarian serous cancer, Jpn J Clin Oncol, 45, 176, 10.1093/jjco/hyu187 Alečković, 2017, Identification of Nidogen 1 as a lung metastasis protein through secretome analysis, Genes Dev, 31, 1439, 10.1101/gad.301937.117 Hanahan, 2011, Hallmarks of cancer: the next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013 Song, 2016, Ultrasound triggered tumor oxygenation with oxygen-shuttle nanoperfluorocarbon to overcome hypoxia-associated resistance in cancer therapies, Nano Lett, 16, 6145, 10.1021/acs.nanolett.6b02365 Sahu, 2020, Improving cancer therapy through the nanomaterials-assisted alleviation of hypoxia, Biomaterials, 228, 119578, 10.1016/j.biomaterials.2019.119578 LaGory, 2016, The ever-expanding role of HIF in tumour and stromal biology, Nat Cell Biol, 18, 356, 10.1038/ncb3330 Han, 2018, Comprehensive and in-depth analysis of microRNA and mRNA expression profile in salivary adenoid cystic carcinoma, Gene, 678, 349, 10.1016/j.gene.2018.08.023 Wang, 2018, The MYB/miR-130a/NDRG2 axis modulates tumor proliferation and metastatic potential in salivary adenoid cystic carcinoma, Cell Death Dis, 9, 10.1038/s41419-018-0966-2 Min, 2011, Shikonin inhibits tumor invasion via down-regulation of NF-κB-mediated MMP-9 expression in human ACC-M cells, Oral Dis, 17, 362, 10.1111/j.1601-0825.2010.01758.x Hsu, 2019, Proteomic profiling of paired interstitial fluids reveals dysregulated pathways and salivary NID1 as a biomarker of oral cavity squamous cell carcinoma, Mol Cell Proteomics, 18, 1939, 10.1074/mcp.RA119.001654 Dongre, 2019, New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer, Nat Rev Mol Cell Biol, 20, 69, 10.1038/s41580-018-0080-4 Hopf, 1999, Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin, Biochem, 259, 917 Willumsen, 2017, Nidogen-1 degraded by cathepsin S can be quantified in serum and is associated with non-small cell lung cancer, Neoplasia, 19, 271, 10.1016/j.neo.2017.01.008 Yurchenco, 2004, Basement membrane assembly, stability and activities observed through a developmental lens, Matrix Biol, 22, 521, 10.1016/j.matbio.2003.10.006 Tian, 2005, Basement membrane proteins play an active role in the invasive process of human hepatocellular carcinoma cells with high metastasis potential, J Cancer Res Clin Oncol, 131, 80, 10.1007/s00432-004-0614-3 Bai, 2020, Analysis of deubiquitinase OTUD5 as a biomarker and therapeutic target for cervical cancer by bioinformatic analysis, PeerJ, 8, e9146, 10.7717/peerj.9146 Han, 2019, STAT3-induced upregulation of lncRNA CASC11 promotes the cell migration, invasion and epithelial-mesenchymal transition in hepatocellular carcinoma by epigenetically silencing PTEN and activating PI3K/AKT signaling pathway, Biochem Biophys Res Commun, 508, 472, 10.1016/j.bbrc.2018.11.092 Rokavec, 2019, Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis, Cell Mol Gastroenterol Hepatol, 7, 783, 10.1016/j.jcmgh.2019.02.003 Kaplan, 2005, VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche, Nature, 438, 820, 10.1038/nature04186 Peinado, 2012, Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET, Nat Med, 18, 883, 10.1038/nm.2753 Vaupel, 2007, Hypoxia in cancer: significance and impact on clinical outcome, Cancer Metast Rev, 26, 225, 10.1007/s10555-007-9055-1 Finger, 2010, inflammation, and the tumor microenvironment in metastatic disease, Cancer Metast Rev, 29, 285, 10.1007/s10555-010-9224-5 Toustrup, 2012, Hypoxia gene expression signatures as prognostic and predictive markers in head and neck radiotherapy, Semin Radiat Oncol, 22, 119, 10.1016/j.semradonc.2011.12.006 Hara, 2006, Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1α in human salivary gland cancer cells, Oral Oncol, 42, 593, 10.1016/j.oraloncology.2005.10.016 Wu, 2015, Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1α/BNIP3 signaling pathway, Mol Med Rep, 12, 6467, 10.3892/mmr.2015.4255 de Mendonça, 2020, Role of hypoxia-related proteins in adenoid cystic carcinoma invasion, Diagn Pathol, 15, 10.1186/s13000-020-00967-3