Guidelines for diagnosis, prevention and treatment of hand eczema

JDDG - Journal of the German Society of Dermatology - Tập 13 Số 1 - 2015
Thomas L. Diepgen1, Klaus E. Andersen2, O. Chosidow3, P.J. Coenraads4, Peter Elsner5, John English6, Manigé Fartasch7, Ana M. Giménez‐Arnau8, Rosemary Nixon9, Denis Sasseville10, Tove Agner11
1Department of Clinical Social Medicine; Occupational and Environmental Medicine; University Hospital Heidelberg; Germany
2Department of Dermatology, University of Southern Denmark, Denmark
3APHP Hôpitaux Universitaires Henri Mondor Créteil France
4Occupational and Environmental Dermatology Unit State University Hospital Groningen The Netherlands
5Clinic for Dermatology and Dermatological Allergology University Hospital Jena Germany
6Department of Dermatology; University of Nottingham; United Kingdom
7Department of Clinical and Experimental Occupational Dermatology, Institute for Prevention and Occupational Medicine, Ruhr University Bochum (IPA), Germany
8Hospital del Mar Parc de Salut Mar Universitat Autonoma Barcelona Spain
9Occupational Dermatological Research & Education Center Victoria Australia
10Royal Victoria Hospital, Montreal, Canada
11University of Copenhagen; Department of Dermatology D; Bispebjerg Hospital; Copenhagen Denmark

Tóm tắt

SummaryThe guidelines aim to provide advice on the management of hand eczema (HE), using an evidence‐ and consensus‐based approach. The guidelines consider a systematic Cochrane review on interventions for HE, which is based on a systematic search of the published literature (including hand‐searching). In addition to the evidence‐ and consensus‐based recommendation on the treatment of HE, the guidelines cover mainly consensus‐based diagnostic aspects and preventive measures (primary and secondary prevention). Treatment recommendations include non‐pharmacological interventions, topical, physical and systemic treatments. Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long‐term treatment beyond six weeks only when necessary and under careful medical supervision. Alitretinoin is recommended as a second line treatment (relative to topical corticosteroids) for patients with severe chronic HE. Randomized control trials (RCT) are missing for other used systemic treatments and comparison of systemic drugs in “head‐to‐head” RCTs are needed.The guidelines development group is a working group of the European Society of Contact Dermatitis (ESCD) and has carefully tried to reconcile opposite views, define current optimal practice and provide specific recommendations, and meetings have been chaired by a professional moderator of the AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften; Association of the Scientific Medical Societies in Germany).No financial support was given by any medical company. The guidelines are expected to be valid until December 2017 at the latest.

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JDDG - Journal of the German Society of Dermatology

Tập 13 Số 1

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