Group-specific component (Gc) subtypes in the Chinese population of Hong Kong

Kim Y. Y. Kwok1, W. H. P. Lewis1
1Institute of Medical and Health Care, Hong Kong Polytechnic, Kowloon, Hong Kong

Tóm tắt

The distribution of Gc subtypes in a sample of the Chinese population of Hong Kong was studied using isoelectric focusing followed by immunofixation. A sensitive modification of this technique is described. Nine distinct phenotypes were observed which appear to result from the three common alleles Gc IF, Gc IS, and Gc 2, which are found in most populations. The respective gene frequencies were 0.494, 0.258, and 0.247. In addition, two rare phenotypes were observed which appear to be due to a rare allele tentatively identified as Gc 2G2.

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Tài liệu tham khảo

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