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Cách tổng hợp xanh nanocomposite chitosan dựa trên vàng và bạc và ứng dụng của chúng trong việc nhận diện chọn lọc ciprofloxacin
Polymer Bulletin - 2024
Tóm tắt
Trong bài báo này, chúng tôi trình bày một nghiên cứu về phim polymer in dấu phân tử (MIP) dựa trên hạt nano vàng (AuNPs) và bạc (AgNPs) hợp nhất với chitosan và ứng dụng của nó để nhận diện/loại bỏ kháng sinh ciprofloxacin (CIP) trong các mẫu thực tế. Vỏ quả lựu được sử dụng ở pH 8 để khử dung dịch nitrat bạc tạo thành AgNPs, trong khi chitosan được sử dụng để khử dung dịch chloride vàng tạo thành AuNPs. Kích thước của AgNPs và AuNPs tổng hợp nằm trong khoảng 30–45 và 45–50 nm, tương ứng, được xác định bằng phương pháp tán xạ ánh sáng động (DLS). Hơn nữa, các hạt nano (NPs) tổng hợp được sử dụng để chuẩn bị phim MIP. Nanocomposite chitosan được thiết kế phân tử dùng làm polymer sinh học chức năng nhằm nâng cao khả năng hấp thụ và diện tích bề mặt của phim MIP. Các đặc tính của composite (Chi@AuMIP và Chi@AgMIP) dựa trên AuNPs và AgNPs chitosan tổng hợp cho thấy khả năng hấp thụ cao hơn nhiều so với polymer không in dấu (NIP). Kết quả cho thấy hằng số cân bằng lý thuyết (KL) và khả năng hấp thụ tối đa (Qmax) theo mô hình Langmuir lần lượt là 12,2 và 20,48 mg g−1 cho Chi@AuMIP và 18,31 và 34,13 mg g−1 cho Chi@AgMIP. Tỷ lệ thu hồi của CIP cho Chi@AuMIP và Chi@AgMIP lần lượt là 98% và 80%. Dữ liệu từ thí nghiệm chọn lọc cho thấy khả năng hấp thụ tối đa của phân tử mục tiêu (CIP) bởi MIP so với các đồng dạng của phân tử mẫu. MIP cho thấy tính chọn lọc tương đối cao và tỷ lệ thu hồi tốt cho CIP trong các mẫu thực tế.
Từ khóa
#chitosan #hạt nano vàng #hạt nano bạc #phim polymer in dấu phân tử #ciprofloxacinTài liệu tham khảo
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