Gold nanoparticles in cancer therapy

Acta Pharmacologica Sinica - Tập 32 Số 8 - Trang 983-990 - 2011
Zhao-Zhin Joanna Lim1, Jia’En Jasmine Li2, Cheng-Teng Ng2, Lin‐Yue Lanry Yung3, Boon‐Huat Bay1
1Department of Anatomy; National University of Singapore; Singapore
2Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore
3Department of Chemical & Biomolecular Engineering, National University of Singapore, Singapore

Tóm tắt

Từ khóa


Tài liệu tham khảo

Cancer [homepage on the Internet]. Geneva: World Health Organization. Accessed Oct 21, 2010. Available from: http://www.who.int/cancer/en/ .

Wagstaff KM, Jans DA . Nuclear drug delivery to target tumour cells. Eur J Pharmacol 2009; 625: 174–80.

Boisselier E, Astruc D . Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity. Chem Soc Rev 2009; 38: 1759–82.

Liu Y, Miyoshi H, Nakamura M . Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles. Int J Cancer 2007; 120: 2527–37.

Lanone S, Boczkowski J . Biomedical applications and potential health risks of nanomaterials: molecular mechanisms. Curr Mol Med 2006; 6: 651–63.

Lewinski N, Colvin V, Drezek R . Cytotoxicity of nanoparticles. Small 2008; 4: 26–49.

Jain KK . The role of nanobiotechnology in drug discovery. Adv Exp Med Biol 2009; 655: 37–43.

DeLong RK, Reynolds CM, Malcolm Y, Schaeffer A, Severs T, Wanekaya A . Functionalized gold nanoparticles for the binding, stabilization, and delivery of therapeutic DNA, RNA, and other biological macromolecules. Nanotechnol Sci Appl 2010; 2010: 53–63.

Kim C, Ghosh P, Rotello V . Multimodal drug delivery using gold nanoparticles. Nanoscale 2009; 1: 61–7.

Cobley CM, Chen J, Cho EC, Wang LV, Xia Y . Gold nanostructures: a class of multifunctional materials for biomedical applications. Chem Soc Rev 2011; 40: 44–56.

Zrazhevskiy P, Gao X . Multifunctional quantum dots for personalized medicine. Nano Today 2009; 4: 414–28.

Biju V, Itoh T, Anas A, Sujith A, Ishikawa M . Semiconductor quantum dots and metal nanoparticles: syntheses, optical properties, and biological applications. Anal Bioanal Chem 2008; 391: 2469–95.

Partha R, Conyers JL . Biomedical applications of functionalized fullerene-based nanomaterials. Int J Nanomedicine 2009; 4: 261–75.

Sun C, Lee JS, Zhang M . Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev 2008; 60: 1252–65.

Sun C, Veiseh O, Gunn J, Fang C, Hansen S, Lee D, et al. In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes. Small 2008; 4: 372–9.

Powell AC, Paciotti GF, Libutti SK . Colloidal gold: a novel nanoparticle for targeted cancer therapeutics. Methods Mol Biol 2010; 624: 375–84.

Connor E, Mwamuka J, Gole A, Murphy C, Wyatt M . Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005; 1: 325–7.

Shukla R, Bansal V, Chaudhary M, Basu A, Bhonde RR, Sastry M . Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview. Langmuir 2005; 21: 10644–54.

Pan Y, Neuss S, Leifert A, Fischler M, Wen F, Simon U, et al. Size-dependent cytotoxicity of gold nanoparticles. Small 2007; 3: 1941–9.

Chen YS, Hung YC, Liau I, Huang GS . Assessment of the in vivo toxicity of gold nanoparticles. Nanoscale Res Lett 2009; 4: 858–64.

Johnston H, Hutchison G, Christensen F, Peters S, Hankin S, Stone V . A review of the in vivo and in vitro toxicity of silver and gold particulates: particle attributes and biological mechanisms responsible for the observed toxicity. Crit Rev Toxicol 2010; 40: 328–46.

Chithrani B, Ghazani A, Chan W . Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett 2006; 6: 662–8.

Pan Y, Leifert A, Ruau D, Neuss S, Bornemann J, Schmid G, et al. Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage. Small 2009; 5: 2067–76.

Li J, Zou L, Hartono D, Ong C, Bay B, Yung L . Gold nanoparticles induce oxidative damage in lung fibroblasts in vitro. Adv Mater 2008; 20: 138–42.

Li J, Hartono D, Ong C, Bay B, Yung L . Autophagy and oxidative stress associated with gold nanoparticles. Biomaterials 2010; 31: 5996–6003.

Tedesco S, Doyle H, Blasco J, Redmond G, Sheehan D . Oxidative stress and toxicity of gold nanoparticles in Mytilus edulis. Aquat Toxicol 2010; 100: 178–86.

Browning L, Lee K, Huang T, Nallathamby P, Lowman J, Xu X . Random walk of single gold nanoparticles in zebrafish embryos leading to stochastic toxic effects on embryonic developments. Nanoscale 2009; 1: 138–52.

De Jong W, Hagens W, Krystek P, Burger M, Sips A, Geertsma R . Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 2008; 29: 1912–9.

Sonavane G, Tomoda K, Makino K . Biodistribution of colloidal gold nanoparticles after intravenous administration: effect of particle size. Colloids Surf B Biointerfaces 2008; 66: 274–80.

Cho W, Cho M, Jeong J, Choi M, Cho H, Han B, et al. Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles. Toxicol Appl Pharmacol 2009; 236: 16–24.

Cho W, Kim S, Han B, Son W, Jeong J . Comparison of gene expression profiles in mice liver following intravenous injection of 4 and 100 nm-sized PEG-coated gold nanoparticles. Toxicol Lett 2009; 191: 96–102.

Kumar S, Harrison N, Richards-Kortum R, Sokolov K . Plasmonic nanosensors for imaging intracellular biomarkers in live cells. Nano Lett 2007; 7: 1338–43.

Sperling R, Rivera Gil P, Zhang F, Zanella M, Parak W . Biological applications of gold nanoparticles. Chem Soc Rev 2008; 37: 1896–908.

Roth J . The silver anniversary of gold: 25 years of the colloidal gold marker system for immunocytochemistry and histochemistry. Histochem Cell Biol 1996; 106: 1–8.

Lee S, Chon H, Lee M, Choo J, Shin S, Lee Y, et al. Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres. Biosens Bioelectron 2009; 24: 2260–3.

Kneipp J, Kneipp H, Wittig B, Kneipp K . Novel optical nanosensors for probing and imaging live cells. Nanomedicine 2010; 6: 214–26.

Kneipp K, Kneipp H, Kneipp J . Surface-enhanced Raman scattering in local optical fields of silver and gold nanoaggregates-from single-molecule Raman spectroscopy to ultrasensitive probing in live cells. Acc Chem Res 2006; 39: 443–50.

Qian X, Peng X, Ansari D, Yin-Goen Q, Chen G, Shin D, et al. In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags. Nat Biotechnol 2008; 26: 83–90.

Cai W, Gao T, Hong H, Sun J . Applications of gold nanoparticles in cancer nanotechnology. Nanotechnol Sci Appl 2008; 1: 17–32.

de la Escosura-Muñiz A, Sánchez-Espinel C, Díaz-Freitas B, González-Fernández A, Maltez-da Costa M, Merkoçi A . Rapid identification and quantification of tumor cells using an electrocatalytic method based on gold nanoparticles. Anal Chem 2009; 81: 10268–74.

Lee SH, Bae KH, Kim SH, Lee KR, Park TG . Amine-functionalized gold nanoparticles as non-cytotoxic and efficient intracellular siRNA delivery carriers. Int J Pharm 2008; 364: 94–101.

Duncan B, Kim C, Rotello VM . Gold nanoparticle platforms as drug and biomacromolecule delivery systems. J Control Release 2010; 148: 122–7.

De Jong W, Borm P . Drug delivery and nanoparticles: applications and hazards. Int J Nanomedicine 2008; 3: 133–49.

Sakamoto J, Annapragada A, Decuzzi P, Ferrari M . Antibiological barrier nanovector technology for cancer applications. Expert Opin Drug Deliv 2007; 4: 359–69.

Zhang G, Yang Z, Lu W, Zhang R, Huang Q, Tian M, et al. Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials 2009; 30: 1928–36.

Bikram M, Gobin AM, Whitmire RE, West JL . Temperature-sensitive hydrogels with SiO2-Au nanoshells for controlled drug delivery. J Control Release 2007; 123: 219–27.

Agasti SS, Chompoosor A, You CC, Ghosh P, Kim CK, Rotello VM . Photoregulated release of caged anticancer drugs from gold nanoparticles. J Am Chem Soc 2009; 131: 5728–9.

Hong R, Han G, Fernandez JM, Kim BJ, Forbes NS, Rotello VM . Glutathione-mediated delivery and release using monolayer protected nanoparticle carriers. J Am Chem Soc 2006; 128: 1078–9.

Paciotti GF, Myer L, Weinreich D, Goia D, Pavel N, McLaughlin RE, et al. Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery. Drug Deliv 2004; 11: 169–83.

Huang X, Jain P, El-Sayed I, El-Sayed M . Plasmonic photothermal therapy (PPTT) using gold nanoparticles. Lasers Med Sci 2008; 23: 217–28.

Koch A, Reynolds F, Merkle H, Weissleder R, Josephson L . Transport of surface-modified nanoparticles through cell monolayers. Chembiochem 2005; 6: 337–45.

van Horssen R, Ten Hagen T, Eggermont A . TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility. Oncologist 2006; 11: 397–408.

Libutti SK, Paciotti GF, Byrnes AA . Alexander HR Jr, Gannon WE, Walker M, et al. Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin Cancer Res 2010; 16: 6139–49.

Visaria R, Griffin R, Williams B, Ebbini E, Paciotti G, Song C, et al. Enhancement of tumor thermal therapy using gold nanoparticle-assisted tumor necrosis factor-alpha delivery. Mol Cancer Ther 2006; 5: 1014–20.

Chen Y, Tsai C, Huang P, Chang M, Cheng P, Chou C, et al. Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model. Mol Pharm 2007; 4: 713–22.

Liu C, Li BQ, Mi CC . Fast transient thermal analysis of gold nanoparticles in tissue-like medium. IEEE Trans Nanobioscience 2009; 8: 271–80.

Link S, El-Sayed MA . Shape and size dependence of radiative, non-radiative and photothermal properties of gold nanocrystals. Int Rev Phys Chem 2000; 19: 409–53.

Loo C, Lowery A, Halas N, West J, Drezek R . Immunotargeted nanoshells for integrated cancer imaging and therapy. Nano Lett 2005; 5: 709–11.

Hainfeld J, Slatkin D, Smilowitz H . The use of gold nanoparticles to enhance radiotherapy in mice. Phys Med Biol 2004; 49: N309–15.

Butterworth KT, Coulter JA, Jain S, Forker J, McMahon SJ, Schettino G, et al. Evaluation of cytotoxicity and radiation enhancement using 1.9 nm gold particles: potential application for cancer therapy. Nanotechnology 2010; 21: 295101.

Hébert E, Debouttière P, Lepage M, Sanche L, Hunting D . Preferential tumour accumulation of gold nanoparticles, visualised by magnetic resonance imaging: Radiosensitisation studies in vivo and in vitro. Int J Radiat Biol 2010; 86: 692–700.

Mukherjee P, Bhattacharya R, Wang P, Wang L, Basu S, Nagy JA, et al. Antiangiogenic properties of gold nanoparticles. Clin Cancer Res 2005; 11: 3530–4.

Bhattacharya R, Mukherjee P . Biological properties of “naked” metal nanoparticles. Adv Drug Deliv Rev 2008; 60: 1289–306.