GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression
Tài liệu tham khảo
Alarid, 1996, Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice, Development, 122, 3319, 10.1242/dev.122.10.3319
Armstrong, 2009, Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the Ca2+/NFAT signaling pathway decode GnRH pulse frequency?, J. Biol. Chem., 284, 35746, 10.1074/jbc.M109.063917
Armstrong, 2009, Gonadotropin-releasing hormone and protein kinase C signaling to ERK: spatiotemporal regulation of ERK by docking domains and dual-specificity phosphatases, Mol. Endocrinol., 23, 510, 10.1210/me.2008-0333
Armstrong, 2010, Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the ERK signaling pathway decode GnRH pulse frequency?, J. Biol. Chem., 285, 24360, 10.1074/jbc.M110.115964
Belchetz, 1978, Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone, Science, 202, 631, 10.1126/science.100883
Benard, 2001, Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone, J. Biol. Chem., 276, 4554, 10.1074/jbc.M006995200
Ben-Menahem, 1994, Regulation of gonadotropin mRNA levels in cultured rat pituitary cells by gonadotropin-releasing hormone (GnRH): role for Ca2+ and protein kinase C, Biochemistry, 33, 3698, 10.1021/bi00178a029
Bernard, 2010, Mechanisms of FSH synthesis: what we know, what we do not, and why you should care, Fertil. Steril., 93, 2465, 10.1016/j.fertnstert.2010.03.034
Blank, 2007, Neuroendocrine effects of androgens in adult polycystic ovary syndrome and female puberty, Semin. Reprod. Med., 25, 352, 10.1055/s-2007-984741
Bliss, 2009, ERK signaling in the pituitary is required for female but not male fertility, Mol. Endocrinol., 23, 1092, 10.1210/me.2009-0030
Bliss, 2010, GnRH signaling, the gonadotrope and endocrine control of fertility, Front. Neuroendocrinol., 31, 322, 10.1016/j.yfrne.2010.04.002
Bonfil, 2004, Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter, Endocrinology, 145, 2228, 10.1210/en.2003-1418
Burger, 2004, Regulation of gonadotropin subunit gene transcription, J. Mol. Endocrinol., 33, 559, 10.1677/jme.1.01600
Burger, 2008, Regulation of intracellular signaling cascades by GNRH pulse frequency in the rat pituitary: roles for CaMK II, ERK, and JNK activation, Biol. Reprod., 79, 947, 10.1095/biolreprod.108.070987
Caunt, 2008, Spatiotemporal regulation of ERK2 by dual specificity phosphatases, J. Biol. Chem., 283, 26612, 10.1074/jbc.M801500200
Ciccone, 2009, The biology of gonadotroph regulation, Curr. Opin. Endocrinol. Diabetes Obes., 16, 321, 10.1097/MED.0b013e32832d88fb
Ciccone, 2008, A composite element that binds basic helix loop helix and basic leucine zipper transcription factors is important for gonadotropin-releasing hormone regulation of the follicle-stimulating hormone beta gene, Mol. Endocrinol., 22, 1908, 10.1210/me.2007-0455
Ciccone, 2010, Frequency-dependent regulation of follicle-stimulating hormone beta by pulsatile gonadotropin-releasing hormone is mediated by functional antagonism of bZIP transcription factors, Mol. Cell. Biol., 30, 1028, 10.1128/MCB.00848-09
Coss, 2004, A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone beta gene by gonadotropin-releasing hormone, J. Biol. Chem., 279, 152, 10.1074/jbc.M304697200
Crawford, 2002, Co-localisation of gonadotrophins and granins in gonadotrophs at different stages of the oestrous cycle in sheep, J. Endocrinol., 174, 179, 10.1677/joe.0.1740179
Crawford, 2002, Promotion of intragranular co-aggregation with LH by enhancement of secretogranin II storage resulted in increased intracellular granule storage in gonadotrophs of GnRH-deprived male mice, Reproduction, 124, 267, 10.1530/rep.0.1240267
Dalkin, 1989, The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression, Endocrinology, 125, 917, 10.1210/endo-125-2-917
Davidson, 1994, Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor, Biochem. J., 300, 299, 10.1042/bj3000299
Denef, 2008, Paracrinicity: the story of 30 years of cellular pituitary crosstalk, J. Neuroendocrinol., 20, 1
Dorn, 1999, Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1, J. Biol. Chem., 274, 13870, 10.1074/jbc.274.20.13870
Duan, 2002, GnRH regulates early growth response protein 1 transcription through multiple promoter elements, Mol. Endocrinol., 16, 221, 10.1210/mend.16.2.0779
Dunaif, 1997, Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis, Endocr. Rev., 18, 774
Fallest, 1991, Acute inhibitory effects of 17 beta-estradiol are observed on gonadotropin secretion from perifused pituitary fragments of metestrous, but not proestrous, rats, Endocrinology, 128, 273, 10.1210/endo-128-1-273
Farnworth, 1995, Gonadotrophin secretion revisited. How many ways can FSH leave a gonadotroph?, J. Endocrinol., 145, 387, 10.1677/joe.0.1450387
Ferris, 2006, Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1, Biol. Reprod., 74, 993, 10.1095/biolreprod.105.049049
Fortin, 2009, Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone beta subunit transcription, Mol. Hum. Reprod., 15, 77, 10.1093/molehr/gan079
Gardner, 2009, Emerging targets of the GnRH receptor: novel interactions with Wnt signalling mediators, Neuroendocrinology, 89, 241, 10.1159/000165377
Garrel, 2010, Sustained gonadotropin-releasing hormone stimulation mobilizes the cAMP/PKA pathway to induce nitric oxide synthase type 1 expression in rat pituitary cells in vitro and in vivo at proestrus, Biol. Reprod., 82, 1170, 10.1095/biolreprod.109.082925
Gharib, 1990, Molecular biology of the pituitary gonadotropins, Endocr. Rev., 11, 177, 10.1210/edrv-11-1-177
Grafer, 2009, GnRH stimulates expression of PACAP in the pituitary gonadotropes via both the PKA and PKC signaling systems, Mol. Endocrinol., 23, 1022, 10.1210/me.2008-0477
Graham, 1999, LbetaT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to active A, J. Endocrinol., 162, 10.1677/joe.0.162R001
Grosse, 2000, Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins, J. Biol. Chem., 275, 9193, 10.1074/jbc.275.13.9193
Haisenleder, 1991, A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo, Endocrinology, 128, 509, 10.1210/endo-128-1-509
Haisenleder, 1997, Gonadotropin subunit and gonadotropin-releasing hormone receptor gene expression are regulated by alterations in the frequency of calcium pulsatile signals, Endocrinology, 138, 5227, 10.1210/endo.138.12.5611
Haisenleder, 2001, Gonadotropin subunit transcriptional responses to calcium signals in the rat: evidence for regulation by pulse frequency, Biol. Reprod., 65, 1789, 10.1095/biolreprod65.6.1789
Haisenleder, 2003, Gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription: evidence for the involvement of calcium/calmodulin-dependent kinase II (Ca/CAMK II) activation in rat pituitaries, Endocrinology, 144, 2768, 10.1210/en.2002-0168
Haisenleder, 2003, The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II, Endocrinology, 144, 2409, 10.1210/en.2002-0013
Halvorson, 1996, Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1, J. Biol. Chem., 271, 6645, 10.1074/jbc.271.12.6645
Han, 1999, The role of protein kinases A and C pathways in the regulation of mitogen-activated protein kinase activation in response to gonadotropin-releasing hormone receptor activation, Endocrinology, 140, 2241, 10.1210/endo.140.5.6707
Hapgood, 2005, Regulation of expression of mammalian gonadotrophin-releasing hormone receptor genes, J. Neuroendocrinol., 17, 619, 10.1111/j.1365-2826.2005.01353.x
Harris, 2002, Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter, Endocrinology, 143, 1018, 10.1210/endo.143.3.8675
Hoffman, 2008, Cardiometabolic features of polycystic ovary syndrome, Nat. Clin. Pract. Endocrinol. Metab., 4, 215, 10.1038/ncpendmet0755
Hsieh, 1992, Thyrotropin-releasing hormone and gonadotropin-releasing hormone receptors activate phospholipase C by coupling to the guanosine triphosphate-binding proteins Gq and G11, Mol. Endocrinol., 6, 1673
Jakubowiak, 1989, Similar effects of inhibin and cycloheximide on gonadotropin release in superfused pituitary cell cultures, Biol. Reprod., 41, 454, 10.1095/biolreprod41.3.454
Kaiser, 1995, A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone, Proc. Natl. Acad. Sci. USA, 92, 12280, 10.1073/pnas.92.26.12280
Kaiser, 1997, Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro, Endocrinology, 138, 1224, 10.1210/endo.138.3.4968
Kaiser, 2000, Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (egr-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-beta gene promoter: an integral role for SF-1, Mol. Endocrinol., 14, 1235
Kakar, 2003, Identification of distinct gene expression profiles associated with treatment of LbetaT2 cells with gonadotropin-releasing hormone agonist using microarray analysis, Gene, 308, 67, 10.1016/S0378-1119(03)00446-3
Kanasaki, 2005, Gonadotropin-releasing hormone pulse frequency-dependent activation of extracellular signal-regulated kinase pathways in perifused LbetaT2 cells, Endocrinology, 146, 5503, 10.1210/en.2004-1317
Kawakami, 2002, Paracrine regulation of FSH by follistatin in folliculostellate cell-enriched primate pituitary cell cultures, Endocrinology, 143, 2250, 10.1210/endo.143.6.8857
Krsmanovic, 2003, An agonist-induced switch in G protein coupling of the gonadotropin-releasing hormone receptor regulates pulsatile neuropeptide secretion, Proc. Natl. Acad. Sci. USA, 100, 2969, 10.1073/pnas.0535708100
Landy, 1991, Altered patterns of pituitary secretion and renal excretion of free alpha-subunit during gonadotropin-releasing hormone agonist-induced pituitary desensitization, J. Clin. Endocrinol. Metab., 72, 711, 10.1210/jcem-72-3-711
Lariviere, 2007, Gonadotropin-releasing hormone couples to 3′,5′-cyclic adenosine-5′-monophosphate pathway through novel protein kinase Cdelta and -epsilon in LbetaT2 gonadotrope cells, Endocrinology, 148, 1099, 10.1210/en.2006-1473
Lawson, 2007, Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2, Mol. Endocrinol., 21, 1175, 10.1210/me.2006-0392
Lee, 1996, Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1), Science, 273, 1219, 10.1126/science.273.5279.1219
Levi, 1998, Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary alpha T3-1 cell line is mediated by protein kinase C, c-Src, and CDC42, Mol. Endocrinol., 12, 815
Lim, 2007, Distinct mechanisms involving diverse histone deacetylases repress expression of the two gonadotropin beta-subunit genes in immature gonadotropes, and their actions are overcome by gonadotropin-releasing hormone, Mol. Cell. Biol., 27, 4105, 10.1128/MCB.00248-07
Lin, 1998, Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH and cyclic adenosine monophosphate, Endocrinology, 139, 3896, 10.1210/endo.139.9.6214
Liu, 2002, GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells, Mol. Endocrinol., 16, 419
Liu, 2002, Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells, J. Biol. Chem., 277, 32099, 10.1074/jbc.M203639200
McArdle, 1995, Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived alpha T3-1 cell line, Endocrinology, 136, 4864, 10.1210/endo.136.11.7588218
McArdle, 1996, Desensitization of gonadotropin-releasing hormone action in alphaT3-1 cells due to uncoupling of inositol 1,4,5-trisphosphate generation and Ca2+ mobilization, J. Biol. Chem., 271, 23711, 10.1074/jbc.271.39.23711
McNeilly, 2003, The differential secretion of FSH and LH: regulation through genes, feedback and packaging, Reproduction, 61, 463
Millar, 2003, GnRH II and type II GnRH receptors, Trends Endocrinol. Metab., 14, 35, 10.1016/S1043-2760(02)00016-4
Millar, 2005, GnRHs and GnRH receptors, Anim. Reprod. Sci., 88, 5, 10.1016/j.anireprosci.2005.05.032
Mistry, 2011, Gonadotropin-releasing hormone pulse sensitivity of follicle-stimulating hormone-beta gene is mediated by differential expression of positive regulatory activator protein 1 factors and corepressors SKIL and TGIF1, Mol. Endocrinol., 25, 1387, 10.1210/me.2011-0032
Mulvaney, 2000, Divergent signaling pathways requiring discrete calcium signals mediate concurrent activation of two mitogen-activated protein kinases by gonadotropin-releasing hormone, J. Biol. Chem., 275, 14182, 10.1074/jbc.275.19.14182
Naor, 2009, Signaling by G-protein-coupled receptor (GPCR): studies on the GnRH receptor, Front. Neuroendocrinol., 30, 10, 10.1016/j.yfrne.2008.07.001
Nicol, 2004, Differential secretion of gonadotrophins: investigation of the role of secretogranin II and chromogranin A in the release of LH and FSH in LbetaT2 cells, J. Mol. Endocrinol., 32, 467, 10.1677/jme.0.0320467
Ooi, 2004, Pituitary cell lines and their endocrine applications, Mol. Cell. Endocrinol., 228, 1, 10.1016/j.mce.2004.07.018
Oosterom, 2005, High-throughput screening using beta-lactamase reporter-gene technology for identification of low-molecular-weight antagonists of the human gonadotropin releasing hormone receptor, Assay Drug Dev. Technol., 3, 143, 10.1089/adt.2005.3.143
Pernasetti, 2001, Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model, Endocrinology, 142, 2284, 10.1210/endo.142.6.8185
Purwana, 2011, Induction of dual-specificity phosphatase 1 (DUSP1) by pulsatile gonadotropin-releasing hormone stimulation: role for gonadotropin subunit expression in mouse pituitary LbetaT2 cells, Biol. Reprod., 84, 996, 10.1095/biolreprod.110.088526
Quirk, 2001, A single Pitx1 binding site is essential for activity of the LHbeta promoter in transgenic mice, Mol. Endocrinol., 15, 734
Roberson, 2005, Gonadotropin-releasing hormone induction of extracellular-signal regulated kinase is blocked by inhibition of calmodulin, Mol. Endocrinol., 19, 2412, 10.1210/me.2005-0094
Savoy-Moore, 1987, Several GnRH stimulation frequencies differentially release FSH and LH from isolated, perfused rat anterior pituitary cells, Adv. Exp. Med. Biol., 219, 641, 10.1007/978-1-4684-5395-9_35
Sealfon, 1997, Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor, Endocr. Rev., 18, 180, 10.1210/edrv.18.2.0295
Seminara, 1998, Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann’s syndrome): pathophysiological and genetic considerations, Endocr. Rev., 19, 521
Stanislaus, 1998, Gonadotropin-releasing hormone receptor couples to multiple G proteins in rat gonadotrophs and in GGH3 cells: evidence from palmitoylation and overexpression of G proteins, Biol. Reprod., 59, 579, 10.1095/biolreprod59.3.579
Takeda, 2007, Effects of peroxisome proliferator-activated receptor activation on gonadotropin transcription and cell mitosis induced by bone morphogenetic proteins in mouse gonadotrope LbetaT2 cells, J. Endocrinol., 194, 87, 10.1677/JOE-07-0138
Thackray, 2010, Hormones in synergy: regulation of the pituitary gonadotropin genes, Mol. Cell. Endocrinol., 314, 192, 10.1016/j.mce.2009.09.003
Thomas, 1996, The L beta T2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion, Endocrinology, 137, 2979, 10.1210/endo.137.7.8770922
Thompson, 2013, GnRH pulse frequency-dependent stimulation of FSHbeta transcription is mediated via activation of PKA and CREB, Mol. Endocrinol., 27, 606, 10.1210/me.2012-1281
Tsutsumi, 2010, Signaling responses to pulsatile gonadotropin-releasing hormone in LbetaT2 gonadotrope cells, J. Biol. Chem., 285, 20262, 10.1074/jbc.M110.132662
Turgeon, 1996, Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line, Mol. Endocrinol., 10, 439
Walsh, 2009, Proteasome regulation of dynamic transcription factor occupancy on the GnRH-stimulated luteinizing hormone beta-subunit promoter, Mol. Endocrinol., 23, 237, 10.1210/me.2008-0098
Wang, 2008, Activator protein-1 and smad proteins synergistically regulate human follicle-stimulating hormone beta-promoter activity, Endocrinology, 149, 5577, 10.1210/en.2008-0220
Washington, 2004, A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH, Theor. Biol. Med. Model., 1, 9, 10.1186/1742-4682-1-9
Watanabe, 1991, Topology of chromogranin A and secretogranin II in the rat anterior pituitary: potential marker proteins for distinct secretory pathways in gonadotrophs, Histochemistry, 96, 285, 10.1007/BF00271348
Weiss, 1990, Gonadotropin-releasing hormone-induced stimulation and desensitization of free alpha-subunit secretion mirrors luteinizing hormone and follicle-stimulating hormone in perifused rat pituitary cells, Endocrinology, 127, 2364, 10.1210/endo-127-5-2364
Wen, 2008, Functional characterization of genetically labeled gonadotropes, Endocrinology, 149, 2701, 10.1210/en.2007-1502
Wildt, 1981, Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey, Endocrinology, 109, 376, 10.1210/endo-109-2-376
Willars, 1999, Lack of a C-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization, J. Biol. Chem., 274, 30146, 10.1074/jbc.274.42.30146
Windle, 1990, Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice, Mol. Endocrinol., 4, 597, 10.1210/mend-4-4-597
Wolfe, 1999, Early growth response protein 1 binds to the luteinizing hormone-beta promoter and mediates gonadotropin-releasing hormone-stimulated gene expression, Mol. Endocrinol., 13, 752
Wu, 2004, Rapid, efficient isolation of murine gonadotropes and their use in revealing control of follicle-stimulating hormone by paracrine pituitary factors, Endocrinology, 145, 5832, 10.1210/en.2004-0257
Wurmbach, 2001, Gonadotropin-releasing hormone receptor-coupled gene network organization, J. Biol. Chem., 276, 47195, 10.1074/jbc.M108716200
Xie, 2005, Transcript profiling of immediate early genes reveals a unique role for activating transcription factor 3 in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone, Mol. Endocrinol., 19, 2624, 10.1210/me.2005-0056
Yehia, 2001, Mitogen-activated protein kinase phosphorylates and targets inducible cAMP early repressor to ubiquitin-mediated destruction, J. Biol. Chem., 276, 35272, 10.1074/jbc.M105404200
Zhang, 2006, Role of MAP kinase phosphatases in GnRH-dependent activation of MAP kinases, J. Mol. Endocrinol., 36, 41, 10.1677/jme.1.01881
Zhang, 2001, Structural organization of the rat mitogen-activated protein kinase phosphatase 2 gene, Gene, 273, 71, 10.1016/S0378-1119(01)00574-1
Zhang, 2001, An early growth response protein (Egr) 1 cis-element is required for gonadotropin-releasing hormone-induced mitogen-activated protein kinase phosphatase 2 gene expression, J. Biol. Chem., 276, 45604, 10.1074/jbc.M107075200