Glycomics – a new target for pharmaceuticals

Drug Discovery Today: Technologies - Tập 3 - Trang 39-47 - 2006
Miyako Nakano1, Akihiro Kondo2, Kazuaki Kakehi3, Naoyuki Taniguchi1
1Department of Biochemistry, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan
2Department of Glycotherapeutics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
3Faculty of Pharmaceutical Sciences, Kinki University, Kowakae 3-4-1, Higashi-osaka 577-8502, Japan

Tài liệu tham khảo

Apweiler, 1999, On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database, Biochim. Biophys. Acta, 1473, 4, 10.1016/S0304-4165(99)00165-8 Taniguchi, 2002 Dwek, 2004, Harnessing changes in cellular glycosylation in new cancer treatment strategies, Curr. Cancer Drug Targets, 4, 425, 10.2174/1568009043332899 Elliott, 2003, Enhancement of therapeutic protein in vivo activities through glycoengineering, Nat. Biotechnol., 21, 414, 10.1038/nbt799 Feizi, 2000, Progress in deciphering the information content of the ‘glycome’–a crescendo in the closing years of the millennium, Glycoconj. J., 17, 553, 10.1023/A:1011022509500 Varki, 1999 Taniguchi, 2001, A glycomic approach to the identification and characterization of glycoprotein function in cells transfected with glycosyltransferase genes, Proteomics, 1, 239, 10.1002/1615-9861(200102)1:2<239::AID-PROT239>3.0.CO;2-K Cohen, 1999, Measuring glycated proteins: clinical and methodological aspects, Diabetes Technol. Ther., 1, 57, 10.1089/152091599317585 Fernandes, 1991, Beta 1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia, Cancer Res., 51, 718 Kobata, 2005, Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours, Immunol. Cell Biol., 83, 429, 10.1111/j.1440-1711.2005.01351.x Wang, 2005, Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice, Proc. Natl. Acad. Sci. U S A, 102, 15791, 10.1073/pnas.0507375102 Kameyama, 2005, A strategy for identification of oligosaccharide structures using observational multistage mass spectral library, Anal. Chem., 77, 4719, 10.1021/ac048350h Nakano, 2003, Sample clean-up method for analysis of complex-type N-glycans released from glycopeptides, J. Chromatogr. A, 1005, 13, 10.1016/S0021-9673(03)00926-9 Anumula, K.R. Advances in fluorescence derivatization methods for high-performance liquid chromatographic analysis of glycoprotein carbohydrates. Anal. Biochem. 10.1016/j.ab.2005.09.037 (http://www.sciencedirect.com/science/journal/00032697) (in press) El Rassi, 1996, Recent advances in capillary electrophoresis of carbohydrates, Electrophoresis, 17, 275, 10.1002/elps.1150170203 Hase, 1994, High-performance liquid chromatography of pyridylaminated saccharides, Methods Enzymol., 230, 225, 10.1016/0076-6879(94)30015-1 Okafo, 1996, A coordinated high-performance liquid chromatographic, capillary electrophoretic, and mass spectrometric approach for the analysis of oligosaccharide mixtures derivatized with 2-aminoacridone, Anal. Chem., 68, 4424, 10.1021/ac960721+ Guile, 1996, A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles, Anal. Biochem., 240, 210, 10.1006/abio.1996.0351 Anumula, 1998, High resolution and high sensitivity methods for oligosaccharide mapping and characterization by normal phase high performance liquid chromatography following derivatization with highly fluorescent anthranilic acid, Glycobiology, 8, 685, 10.1093/glycob/8.7.685 Nakano, 2004, Detailed structural features of glycan chains derived from alpha1-acid glycoproteins of several different animals: the presence of hypersialylated. O-acetylated sialic acids but not disialyl residues, Glycobiology, 14, 431, 10.1093/glycob/cwh034 Kakehi, 1999, 3-Aminobenzamide and 3-aminobenzoic acid, tags for capillary electrophoresis of complex carbohydrates with laser-induced fluorescent detection, J. Chromatogr. A, 863, 205, 10.1016/S0021-9673(99)00978-4 Lamari, 2003, Derivatization of carbohydrates for chromatographic, electrophoretic and mass spectrometric structure analysis, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 793, 15, 10.1016/S1570-0232(03)00362-3 Packer, 1998, A general approach to desalting oligosaccharides released from glycoproteins, Glycoconj. J., 15, 737, 10.1023/A:1006983125913 Okuyama, N. et al. Fucosylated haptoglobin is a novel marker for pancreatic cancer: a detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation. Int. J. Cancer. 10.1002/ijc.21728 (http://www3.interscience.wiley.com/cgi-bin/jhome/29331) (in press) Raman, 2005, Glycomics: an integrated systems approach to structure-function relationships of glycans, Nat. Methods, 2, 817, 10.1038/nmeth807 Kamoda, 2005, Rapid and sensitive screening of N-glycans as 9-fluorenylmethyl derivatives by high-performance liquid chromatography: a method which can recover free oligosaccharides after analysis, J. Proteome Res., 4, 146, 10.1021/pr049825o Willats, 2002, Sugar-coated microarrays: a novel slide surface for the high-throughput analysis of glycans, Proteomics, 2, 1666, 10.1002/1615-9861(200212)2:12<1666::AID-PROT1666>3.0.CO;2-E Xia, 2005, Versatile fluorescent derivatization of glycans for glycomic analysis, Nat. Methods, 2, 845, 10.1038/nmeth808 Takegawa, 2005, Simultaneous analysis of 2-aminopyridine-derivatized neutral and sialylated oligosaccharides from human serum in the negative-ion mode by sonic spray ionization ion trap mass spectrometry, Anal. Chem., 77, 2097, 10.1021/ac048499t Nakajima, 2003, Capillary affinity electrophoresis for the screening of post-translational modification of proteins with carbohydrates, J. Proteome Res., 2, 81, 10.1021/pr020009v Naka, 2006, Analysis of total N-glycans in cell membrane fractions of cancer cells using a combination of serotonin affinity chromatography and normal phase chromatography, J. Proteome Res., 5, 88, 10.1021/pr0502976 Furukawa, 2001, Novel functions of complex carbohydrates elucidated by the mutant mice of glycosyltransferase genes, Biochim. Biophys. Acta, 1525, 1, 10.1016/S0304-4165(00)00185-9 Ishibashi, 2005, Expression of N-acetylglucosaminyltransferase V in the development of human esophageal cancers: immunohistochemical data from carcinomas and nearby noncancerous lesions, Oncology, 69, 301, 10.1159/000089680 Taniguchi, 2001, Implication of GnT-V in cancer metastasis: a glycomic approach for identification of a target protein and its unique function as an angiogenic cofactor, Glycoconj. J., 18, 859, 10.1023/A:1022292223878 Itzkowitz, 1986, Lewisx- and sialylated Lewisx-related antigen expression in human malignant and nonmalignant colonic tissues, Cancer Res., 46, 2627 Hardy, 1988, Monosaccharide analysis of glycoconjugates by anion exchange chromatography with pulsed amperometric detection, Anal. Biochem., 170, 54, 10.1016/0003-2697(88)90089-9 Townsend, 1991, Analysis of glycoprotein oligosaccharides using high-pH anion exchange chromatography, Glycobiology, 1, 139, 10.1093/glycob/1.2.139 Zaia, 2004, Mass spectrometry of oligosaccharides, Mass Spectrom. Rev., 23, 161, 10.1002/mas.10073 Smyth, 2004, Electrophoresis, 25, 1413, 10.1002/elps.200305850 Zamfir, 2004, Capillary electrophoresis-mass spectrometry for glycoscreening in biomedical research, Electrophoresis, 25, 1949, 10.1002/elps.200405825