Glycogen concentration changes in retina, vitreous body and other eye tissues caused by disturbances of blood circulation
Tóm tắt
The glycogen content in the individual eye tissues is strongly correlated to blood supply. Our investigations on the retina of bovines, which have not been fully evaluated, show that the time interval between interruption of blood supply and preparation of the retina is of special importance. Pressure ischemia affects a decrease in glycogen content in the retina and vitreous of rabbits, which is, however, less distinct in the vitreous. Decrease of glycogen with ischemia also takes place in the cornea and, to a lesser degree, in iris and choroid. In contrast, there is no decrease in the glycogen content of the lens. Changes in glycogen content of the rabbit retina after ligation of the A. carotis communis is less distinct than with pressure ischemia. in the vitreous, changes in glycogen content could not be observed. Values measured in both tissues of the ligated eye decrease with additional pressure ischemia.
Tài liệu tham khảo
albaum, H. G., Werner, K. M., Chinn, H. J.: Chemical changes in rabbit brain during anoxia. Amer. J. Physiol.174, 408–412 (1953)
Bergmeyer, H. U.: Methoden der enzymatischen Analyse, 2. Aufl., vol. II. Weinheim/Bergstraße: Verlag Chemie 1970
Bleeker, G. M., Haeringen, N. J. van, Glasius, E.: Selective properties of the vitreous barrier. Exp. Eye Res.7, 37–46 (1968)
Böck, J., Bornschein, H., Hommer, K.: Experimentelle Untersuchungen über eine transvitreale Beeinflussung des Elektroretinogrammes. Docum. ophthal. (Den Haag)16, 35–53 (1962)
Kaskel, D., Hockwin, O., Metzler, U., Schedtler, C.-M.: Glycogen content in the rabbit retina in relation to blood circulation. Ophthal. Res.5, 177–185 (1973)
Leschkevitch, L. G.: Utilization of the glycogen of the muscles and internal organs under physical strain of extreme duration. Fiziol. J. UDSSR37, 475 (1951)
Oberhoff, P., Hockwin, O.: The ATP content of the retina in relation to the blood circulation. Albrecht v. Graefes Arch. klin. exp. Ophthal.178, 329–332 (1969)
Vassileva, P.: Changes in the glycogen content in the retina of the rabbit during experimental ischaemia. 2. Wissenschaftliche Nationalkonferenz der Aspiranten. Medizina i Fiskultura, Sofia 1969, p. 95–101
Vassileva, P., Dabov, B.: Changes in the glycogen content and the ERG in retina ischaemia experimentally induced in rabbits. Proc. 3rd Mackenzie Symp. Glasgow, 1974 (in press)
Weiss, H.: The carbohydrate reserve in the vitreous body and retina of the rabbit eye during and after pressure ischaemia and insulin hypoglycaemia. Ophthal. Res.3, 360–371 (1972)