Glutathione transferase kappa deficiency causes glomerular nephropathy without overt oxidative stress

Laboratory Investigation - Tập 91 - Trang 1572-1583 - 2011
Anneke C Blackburn1, Marjorie Coggan1, Alison J Shield1,2, Jean Cappello1, Angelo Theodoratos1, Tracy P Murray1, Melissa Rooke1, Claire Z Larter3, Mark E Koina4, Jane E Dahlstrom1,3,4, Klaus I Matthaei1, Philip G Board1
1John Curtin School of Medical Research, Australian National University, Canberra, Australia
2Faculty of Health, University of Canberra, Canberra, Australia
3ANU Medical School, The Canberra Hospital, Canberra, Australia
4Department of Anatomical Pathology, The Canberra Hospital, Canberra, Australia

Tài liệu tham khảo

Morel, 2004, Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization, J Biol Chem, 279, 16246, 10.1074/jbc.M313357200 Jowsey, 2003, Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase, Biochem J, 373, 559, 10.1042/bj20030415 Robinson, 2004, Modelling and bioinformatics studies of the human kappa class glutathione transferase predict a novel third glutathione transferase family with homology to prokaryotic 2-hydroxychromene-2-carboxylate (HCCA) isomerases, Biochem J, 379, 541, 10.1042/bj20031656 Ladner, 2004, Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1, Biochemistry, 43, 352, 10.1021/bi035832z Thomson, 2004, Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa, J Histochem Cytochem, 52, 653, 10.1177/002215540405200509 Kuhm, 1993, Purification and properties of 2′-hydroxybenzalpyruvate aldolase from a bacterium that degrades naphthalenesulfonates, J Biol Chem, 268, 9484, 10.1016/S0021-9258(18)98376-6 Thomas, 1987, Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells, Cell, 51, 503, 10.1016/0092-8674(87)90646-5 Lim, 2004, Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases, Am J Pathol, 165, 679, 10.1016/S0002-9440(10)63332-9 Habig, 1974, Glutathione S-transferases. The first enzymatic step in mercapturic acid formation, J Biol Chem, 249, 7130, 10.1016/S0021-9258(19)42083-8 Mannervik, 1995, Human glutathione transferases: classification, tissue distribution, structure and functional properties, 407 Baker, 1990, Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples, Anal Biochem, 190, 360, 10.1016/0003-2697(90)90208-Q Blackburn, 2006, Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways, Mol Pharmacol, 69, 650, 10.1124/mol.105.018911 Jo, 2007, Puromycin induces reversible proteinuric injury in transgenic mice expressing cyclooxygenase-2 in podocytes, Nephron Exp Nephrol, 107, e87, 10.1159/000108653 Sharma, 1993, Comparative studies on the effect of butylated hydroxyanisole on glutathione and glutathione S-transferases in the tissues of male and female CD-1 mice, Comp Biochem Physiol C, 105, 31, 10.1016/0742-8413(93)90053-N Engle, 2004, Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse, Toxicol Appl Pharmacol, 194, 296, 10.1016/j.taap.2003.10.001 Chen, 1998, Involvement of immunopathogenic mechanisms in a spontaneously occurring glomerulopathy in mice, Nephron, 78, 63, 10.1159/000044884 Bargman, 1999, Management of minimal lesion glomerulonephritis: evidence-based recommendations, Kidney Int Suppl, 70, S3, 10.1046/j.1523-1755.1999.07002.x Cattran, 2005, Management of membranous nephropathy: when and what for treatment, J Am Soc Nephrol, 16, 1188, 10.1681/ASN.2005010028 Asanuma, 2003, The role of podocytes in glomerular pathobiology, Clin Exp Nephrol, 7, 255, 10.1007/s10157-003-0259-6 Liu, 2008, A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization, Proc Natl Acad Sci U S A, 105, 18302, 10.1073/pnas.0806341105 Sharma, 2008, Adiponectin regulates albuminuria and podocyte function in mice, J Clin Invest, 118, 1645 Savige, 1991, Hereditary abnormalities of renal basement membranes, Pathology, 23, 350, 10.3109/00313029109063604 Olson, 2007, 136 Mathieson, 2004, The cellular basis of albuminuria, Clin Sci (Lond), 107, 533, 10.1042/CS20040168 Koop, 2003, Expression of podocyte-associated molecules in acquired human kidney diseases, J Am Soc Nephrol, 14, 2063, 10.1097/01.ASN.0000078803.53165.C9 Jarad, 2006, Proteinuria precedes podocyte abnormalities inLamb2−/− mice, implicating the glomerular basement membrane as an albumin barrier, J Clin Invest, 116, 2272, 10.1172/JCI28414 Harris, 1991, A novel glutathione transferase (13-13) isolated from the matrix of rat liver mitochondria having structural similarity to class theta enzymes, Biochem J, 278, 137, 10.1042/bj2780137 Peng, 2008, Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease, PLoS Genet, 4, e1000061, 10.1371/journal.pgen.1000061 Diomedi-Camassei, 2007, COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement, J Am Soc Nephrol, 18, 2773, 10.1681/ASN.2006080833 Holthofer, 1999, Altered gene expression and functions of mitochondria in human nephrotic syndrome, Faseb J, 13, 523, 10.1096/fasebj.13.3.523 Solin, 2000, Mitochondrial dysfunction in congenital nephrotic syndrome, Lab Invest, 80, 1227, 10.1038/labinvest.3780130 Krick, 2008, Mpv17 l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease, Proc Natl Acad Sci USA, 105, 14106, 10.1073/pnas.0801146105 Weiher, 1990, Transgenic mouse model of kidney disease: insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome, Cell, 62, 425, 10.1016/0092-8674(90)90008-3 Binder, 1999, Glomerular overproduction of oxygen radicals in Mpv17 gene-inactivated mice causes podocyte foot process flattening and proteinuria: A model of steroid-resistant nephrosis sensitive to radical scavenger therapy, Am J Pathol, 154, 1067, 10.1016/S0002-9440(10)65359-X O'Bryan, 2000, Course of renal injury in the Mpv17-deficient transgenic mouse, J Am Soc Nephrol, 11, 1067, 10.1681/ASN.V1161067 Meyer zum Gottesberge, 1996, Inner ear defect similar to Alport's syndrome in the glomerulosclerosis mouse model Mpv17, Eur Arch Otorhinolaryngol, 253, 470, 10.1007/BF00179952 Smithies, 2003, Why the kidney glomerulus does not clog: a gel permeation/diffusion hypothesis of renal function, Proc Natl Acad Sci USA, 100, 4108, 10.1073/pnas.0730776100 Petit, 2009, Glutathione transferases kappa 1 and kappa 2 localize in peroxisomes and mitochondria, respectively, and are involved in lipid metabolism and respiration in Caenorhabditis elegans, Febs J, 276, 5030, 10.1111/j.1742-4658.2009.07200.x