Glutathione-dependent detoxification of α-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors

Chemico-Biological Interactions - Tập 111-112 - Trang 137-151 - 1998
Paul J. Thornalley1
1Department of Biological & Chemical Sciences, University of Essex, Colchester, UK.

Tóm tắt

Từ khóa


Tài liệu tham khảo

Thornalley, 1993, The glyoxalase system in health and disease, Mol. Asp. Med., 14, 287, 10.1016/0098-2997(93)90002-U

Loidl-Stahlhofen, 1994, Hydroxyaldehydes, products of lipid peroxidation, Biochim. Biophys. Acta, 1211, 156, 10.1016/0005-2760(94)90264-X

Wells-Knecht, 1995, Mechanism of autoxidative glycosylation: Identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose, J. Am. Chem. Soc., 34, 3702

Glomb, 1995, Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction, J. Biol. Chem., 276, 10017, 10.1074/jbc.270.17.10017

Phillips, 1993, The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal, Eur. J. Biochem., 212, 101, 10.1111/j.1432-1033.1993.tb17638.x

Pompliano, 1990, Stabilization of a reaction intermediate as a catalytic device: Definition of the functional role of the flexible loop in triosephosphate isomerase, Biochemistry, 29, 3186, 10.1021/bi00465a005

Ray, 1981, Isolation of methylglyoxal synthase goat liver, J. Biol. Chem., 256, 6230, 10.1016/S0021-9258(19)69151-9

Koop, 1985, Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes, J. Biol. Chem., 260, 13607, 10.1016/S0021-9258(17)38768-9

Lyles, 1992, The metabolism of aminoacetone to methylglyoxal by semicarbazide-sensitive amino oxidase in human umbilical artery, Biochem. Pharmacol., 43, 1409, 10.1016/0006-2952(92)90196-P

Jerzykowski, 1979, Dioxovalerate as a substrate for the glyoxalase enzyme system, Biochemistry, 135, 713, 10.1042/bj1350713

Thornalley, 1996, Negative association of red blood cell reduced glutathione with diabetic complications, Clin. Sci., 91, 575, 10.1042/cs0910575

McLellan, 1994, The glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications, Clin. Sci., 87, 21, 10.1042/cs0870021

Papoulis, 1995, Identification of N2-(1-carboxyethyl)guanine (CEG) as a guanine advanced glycosylation endproduct, Biochemistry, 34, 648, 10.1021/bi00002a032

Vaca, 1994, Development of a 32P-postlabelling technique for the analysis of 2′-deoxyguanosine-3′-monophosphate and DNA of methylglyoxal, Carcinogenesis, 15, 1887, 10.1093/carcin/15.9.1887

Nukaya, 1993, Modification of the amino group of guanosine by methylglyoxal and other α-ketoaldehydes in the presence of H2O2, Chem. Pharm. Bull., 41, 649, 10.1248/cpb.41.649

Thornalley, 1995, Crit. Rev. Oncol. Haematol., 20, 99, 10.1016/1040-8428(94)00149-N

Kang, 1996, Effect of methylglyoxal on human leukaemia 60 cell growth: modification of DNA, G1 growth arrest and induction of apoptosis, Leuk. Res., 20, 397, 10.1016/0145-2126(95)00162-X

Hiraku, 1997, Mechanism of oxidative DNA damage induced by δ-aminolevulinic acid in the presence of copper ion, Cancer Res., 56, 1786

Vince, 1969, Glyoxalase inhibitors as potential anticancer agents, Biochem. Biophys. Res. Commun., 35, 593, 10.1016/0006-291X(69)90445-8

Lo, 1992, Inhibition of proliferation of human leukemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro, Biochem. Pharmacol., 44, 2357, 10.1016/0006-2952(92)90680-H

Thornalley, 1996, Antitumour activity of S-p-bromobenzylglutathione diesters in vitro: a structure activity study, J. Med. Chem., 39, 3409, 10.1021/jm960129c

Thornalley, 1996, Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo. Inhibition of glyoxalase I and induction of apoptosis, Biochem. Pharmacol., 51, 1365, 10.1016/0006-2952(96)00059-7

Moldeus, 1994, N-Acetylcysteine, Methods Enzymol., 234, 482, 10.1016/0076-6879(94)34119-2

Thornalley, 1994, Anti-malarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester, Biochem. Pharmacol., 268, 14189

Thornalley, 1988, Modification of the glyoxalase system in human red blood cells by glucose in vitro, Biochem. J., 254, 751, 10.1042/bj2540751

Phillips, 1993, Modification of the glyoxalase system in streptozotocin-induced diabetic rats; effect of the aldose reductase inhibitor Statil, Biochem. Pharmacol., 46, 805, 10.1016/0006-2952(93)90488-I

Donnini, 1996, Glucose may induce cell death through a free radical-mediated mechanism, Biochem. Biophys. Res. Commun., 219, 412, 10.1006/bbrc.1996.0247

Shinohara, 1996, Overexpression of glyoxalase I inhibits intracellular advanced glycation endproduct (AGE) formation, Diabetes, 45, 126A

Lo, 1994, Reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins, Biochem. Pharmacol., 48, 1865, 10.1016/0006-2952(94)90584-3

Thornalley, 1996, Advanced glycation and the development of diabetic complications. Unifying the involvement of glucose, methylglyoxal and oxidative stress, Endocrinol. Metab., 3, 149

Lo, 1994, Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with Nα-acetylarginine, Nα-acetylcysteine, Nα-acetyl-lysine, and bovine serum albumin, J. Biol. Chem., 269, 32299, 10.1016/S0021-9258(18)31635-1

Henle, 1994, Detection and identification of a protein-bound imidazolone resulting from the reaction of arginine residues and methylglyoxal, Z. Lebensm. Unters. Forsch, 199, 55, 10.1007/BF01192954

Nagaraj, 1996, Protein cross-linking by the Maillard reaction. Isolation, characterization, and in vivo detection of a lysine–lysine cross-link derived from methylglyoxal, J. Biol. Chem., 271, 19338, 10.1074/jbc.271.32.19338

Ahmed, 1997, Nε-(2-Carboxyethyl)lysine, a product of chemical modification of proteins by methylglyoxal, increases with age in human lens proteins, Biochem. J., 324, 565, 10.1042/bj3240565

Griffith, 1980, The apparent glutathione oxidase activity of gamma-glutamyl transpeptidase, J. Biol. Chem., 255, 5011, 10.1016/S0021-9258(19)70739-X

McLellan, 1992, The assay of methylglyoxal in biological systems by derivatization with 1,2-diamino-4,5-dimethoxybenzene, Anal. Biochem., 206, 17, 10.1016/S0003-2697(05)80005-3

Westwood, 1997, Methylglyoxal-modified arginine residues-a signal for receptor-mediated endocytosis and degradation of proteins by monocytic THP-1 cells, Biochim. Biophys. Acta, 1356, 84, 10.1016/S0167-4889(96)00154-1

Westwood, 1996, Induction of synthesis and secretion of interleukin 1( in the human monocytic leukaemia THP-1 cells by human serum albumins modified with methylglyoxal and advanced glycation endproducts, Immunol. Lett., 50, 17, 10.1016/0165-2478(96)02496-0

Westwood, 1994, Receptor-mediated endocytic uptake of methylglyoxal-modified proteins, J. Biol. Chem., 269, 32293, 10.1016/S0021-9258(18)31634-X

Shinoda, 1993, Uptake of proteins modified with 3-deoxyglucosone, a Maillard reaction intermediate, by the type I macrophage scavenger receptor, Biosci. Biotech. Biochem., 57, 1826, 10.1271/bbb.57.1826

Araki, 1995, Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end-products of the Maillard reaction, Eur. J. Biochem., 230, 408, 10.1111/j.1432-1033.1995.0408h.x

Schmidt, 1994, The endothelial cell binding site for advanced glycation endproducts consists of a complex: An integral membrane protein and a lactoferrin-like polypeptide, J. Biol. Chem., 269, 9882, 10.1016/S0021-9258(17)36965-X

Abordo, 1996, Synthesis and secretion of macrophage colony stimulating factor by mature human monocytes and human monocytic THP-1 cells induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts, Immunol. Lett., 53, 7, 10.1016/0165-2478(96)02601-6

Abordo, 1996, Human serum albumin minimally-modified by methylglyoxal but not by glucose-derived advanced glycation endproducts induced the synthesis and secretion of tumour necrosis factor-α (TNFα) by human monocytic THP-1 cells in vitro, Diabetes, 45, 129A

McCance, 1993, Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus, J. Clin. Invest., 91, 2470, 10.1172/JCI116482

Lyons, 1991, Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts, Diabetes, 40, 1010, 10.2337/diab.40.8.1010

Vlassara, 1992, Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: A model for diabetic and aging complications, Proc. Natl. Acad. Sci. USA, 89, 12043, 10.1073/pnas.89.24.12043

Vitek, 1994, Advanced glycation end products contribute to amyloidosis in Alzheimer disease, Proc. Natl. Acad. Sci. USA, 91, 4766, 10.1073/pnas.91.11.4766

Miyata, 1993, β2-Microglobulin modified with advanced glycation end products is a major component of haemodialysis-associated amyloidosis, J. Clin. Invest., 92, 1243, 10.1172/JCI116696

Monteiro, 1989, Free radical generation during δ-aminolevulinic acid autooxiadtion: induction by hemoglobin and connections with porphyrinopathies, Arch. Biochem. Biophys., 271, 206, 10.1016/0003-9861(89)90271-3