Glutamate/Aspartate Transporter (GLAST), Taurine Transporter and Metallothionein mRNA Levels are Differentially Altered in Astrocytes Exposed to Manganese Chloride, Manganese Phosphate or Manganese Sulfate

NeuroToxicology - Tập 23 - Trang 281-288 - 2002
Keith M. Erikson1, Robert L. Suber1, Michael Aschner1
1Department of Physiology and Pharmacology, School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1083, USA

Tài liệu tham khảo

Aoyama, 2001, Expression of metallothionein in liver and kidney of rats is influenced by excess dietary histidine, Comp. Biochem. Physiol. C Toxicol. Pharmacol., 128, 339, 10.1016/S1532-0456(00)00212-X Aschner, 1996, The functional significance of brain metallothioneins, FASEB J., 10, 1129, 10.1096/fasebj.10.10.8751715 Aschner, 1992, Manganese (Mn) uptake and efflux in cultured rat astrocytes, J. Neurochem., 58, 730, 10.1111/j.1471-4159.1992.tb09778.x Aschner, 2001, Aspartate and glutamate transport in acutely and chronically ethanol exposed neonatal rat primary astrocyte cultures, Neurotoxicology, 44, 1 Barbu, 1989, Northern blot normalization with a 28s rRNA oligonucleotide probe, Nucl. Acids Res., 17, 7115, 10.1093/nar/17.17.7115 Bitoun, 2000, Gene expression of the transporters and biosynthetic enzymes of the osmolytes in astrocyte primary cultures exposed to hyperosmotic conditions, Glia, 32, 165, 10.1002/1098-1136(200011)32:2<165::AID-GLIA60>3.0.CO;2-2 Brouillet, 1993, Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism, Exp. Neurol., 120, 89, 10.1006/exnr.1993.1042 Cherian, 1997, Metallothionein in brain—the role in physiology and pathology, Toxicol. Appl. Pharmacol., 1142, 229 Choi, 1988, Glutamate neurotoxicity and diseases of the central nervous system, Neuron, 1, 623, 10.1016/0896-6273(88)90162-6 Cotzias, 1968, Chronic manganese poisoning. Clearance of tissue manganese concentrations with persistence of the neurological picture, Neurology, 18, 376, 10.1212/WNL.18.4.376 Danbolt, 2001, Glutamate uptake, Prog. Neurobiol., 65, 1, 10.1016/S0301-0082(00)00067-8 Davis, 1998, Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in c6 glioma, J. Neurosci., 18, 2475, 10.1523/JNEUROSCI.18-07-02475.1998 Desole, 1997, Glutathione deficiency potentiates manganese toxicity in rat striatum and brainstem and in PC12 cells, Pharmacol. Res., 36, 285, 10.1006/phrs.1997.0197 Dorman, 2001, Influence of particle solubility on the delivery of inhaled manganese to the rat brain: manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure, Toxicol. Appl. Pharmacol., 170, 79, 10.1006/taap.2000.9088 Drown, 1986, Pulmonary clearance of soluble and insoluble forms of manganese, J. Toxicol. Environ. Health, 17, 201, 10.1080/15287398609530816 Dunn, 1987, Metallothionein, Proc. Soc. Exp. Biol. Med., 185, 107, 10.3181/00379727-185-42525A Durnam, 1987, Analysis of the detoxificication of heavy metal ions by mouse metallothionein, Exp. Suppl., 52, 457, 10.1007/978-3-0348-6784-9_45 Erikson KM, Aschner M. Manganese causes differential regulation of glutamate transporter (GLAST), taurine transporter, and metallothionein in cultured rat astrocytes. Neurotoxicology, 2002;23:in press. Frangakis, 1984, Dissociation of neonatal rat brain by Dispase for preparation of primary astrocyte cultures, Neurochem. Res., 9, 1689, 10.1007/BF00968079 Hakkinen, 1983, Potentiating effects of oxygen in lungs damaged by MMT, cadmium chloride, oleic acid and antitumor drugs, Toxicol. Appl. Pharmacol., 67, 55, 10.1016/0041-008X(83)90244-2 Hazell, 1997, Manganese decreases glutamate uptake in cultured astrocytes, Neurochem. Res., 22, 1443, 10.1023/A:1021994126329 Ingersoll, 1999, Central nervous system toxicity of manganese. II. Cocaine or reserpine inhibit manganese concentration in the rat brain, Neurotoxicology, 20, 467 Katakai, 2001, Nitric oxide induces metallothionein (MT) gene expression appartently by displacing zinc bound to MT, Toxicol. Lett., 119, 103, 10.1016/S0378-4274(00)00301-5 Kondo, 1995, Expression of glutamate transporters in cultured glial cells, Neursci. Lett., 188, 140, 10.1016/0304-3940(95)11408-O Lai, 1999, Manganese mineral interactions in brain, Neurotoxicology, 20, 433 Logroscino, 1997, Altered systemic iron metabolism in Parkinson’s disease, Neurology, 49, 714, 10.1212/WNL.49.3.714 Lynam, 1999, Environmental effects and exposures to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline, Neurotoxicology, 20, 145 Maret, 1994, Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange, Proc. Natl. Acad. Sci. U.S.A., 91, 237, 10.1073/pnas.91.1.237 Martin, 1992, Synthesis and release of neuroactive substances by glial cells, Glia, 5, 81, 10.1002/glia.440050202 Miele, 2000, Glutamate and catabolites of high energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese, Aging, 12, 393 Montes, 2001, Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat, Brain Res., 891, 123, 10.1016/S0006-8993(00)03208-X Ottersen, 1992, Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum, Neuroscience, 46, 519, 10.1016/0306-4522(92)90141-N Roels, 1997, Influence of the route of administration and the chemical form (MnCl2, MnO2) on the absorption and cerebral distribution of manganese in rats, Arch. Toxicol., 71, 223, 10.1007/s002040050380 Sierra, 1995, Occupational and environmental exposure of automobile mechanics and nonautomotive workers to airborne manganese arising from the combustion of MMT, Am. Ind. Hyg. Assoc., 56, 713, 10.1080/15428119591016746 Smith, 1992, Cloning and expression of high affinity taurine transporter from rat brain, Mol. Pharmacol., 42, 563 Stokes, 2000, Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis, Brain Res., 858, 1, 10.1016/S0006-8993(99)02329-X Suzuki, 1975, Study of substance toxicity of manganese dioxide in monkeys, Tokushima J. Exp. Med., 22, 5 Van den Berg, 1971, A simulation study of brain compartments—metabolism of glutamate and related substances in mouse brain, Biochem. J., 123, 211, 10.1042/bj1230211 Vitarella, 1994, Potassium and taurine release are highly correlated with regulatory volume decrease in neonatal primary rat astrocyte cultures, J. Neurochem., 63, 1143, 10.1046/j.1471-4159.1994.63031143.x Vitarella, 2000, Pharmacokinetics of inhaled manganese phosphate in male Sprague–Dawley rats following subacute (14-day) exposure, Toxicol. Appl. Pharmacol., 163, 279, 10.1006/taap.1999.8874 Westergaard, 1995, Metabolic trafficking between neurons and astrocytes: the glutamate glutamine cycle revisited, Dev. Neurosci., 17, 203, 10.1159/000111288 Zayed, 1999, Characterization of manganese-containing particles collected form the exhaust emissions of automobiles running with MMT additive, Environ. Sci. Technol., 33, 3341, 10.1021/es990709+ Zheng, 1999, Alteration of iron homeostasis following chronic exposure to manganese in rats, Brain Res., 833, 125, 10.1016/S0006-8993(99)01558-9