Glomeruläre Läsionen bei Transplantatabstoßung

Der Nephrologe - Tập 3 - Trang 222-228 - 2008
H. Hopfer1, S. Schaub2, M.J. Mihatsch1
1Institut für Pathologie, Universitätsspital Basel, Basel, Schweiz
2Klinik für Nephrologie und Transplantationsimmunologie, Universitätsspital Basel, Basel, Schweiz

Tóm tắt

Abstoßungsreaktionen sind die häufigste Ursache für ein Transplantatversagen nach Nierentransplantation. Glomeruläre Läsionen finden sich dabei relativ selten. Die thrombotische Mikroangiopathie und die Transplantatglomerulitis treten früh nach Transplantation auf, die Transplantatglomerulopathie bildet sich in der Regel erst nach längerer Zeit aus. Die morphologischen Befunde, in deren Zentrum ein Endothelschaden steht, und mögliche pathogenetische Mechanismen werden diskutiert.

Tài liệu tham khảo

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