Global increase and geographic convergence in antibiotic consumption between 2000 and 2015

Proceedings of the National Academy of Sciences of the United States of America - Tập 115 Số 15 - 2018
Eili Klein1,2,3, Thomas P. Van Boeckel4, Elena Martínez5, Suraj Pant5, Sumanth Gandra5, Simon A. Levin6,7,8, Herman Goossens9, Ramanan Laxminarayan10,11,8
1Center for Disease Dynamics, Economics & Policy, Washington, DC 20005;; Department of Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21209;
2Department of Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21209;
3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205
4Institute of Integrative Biology, ETH Zürich, CH-8006 Zürich, Switzerland;
5Center for Disease Dynamics, Economics & Policy, Washington, DC 20005;
6Beijer Institute of Ecological Economics, SE-104 05 Stockholm, Sweden;
7Beijer Institute of Ecological Economics, SE-104 05 Stockholm, Sweden;; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544;
8Princeton Environmental Institute, Princeton University, Princeton, NJ 08544;
9Laboratory of Medical Microbiology, Vaccine & Infectious Diseases Institute, University of Antwerp, 2610 Antwerp, Belgium;
10Center for Disease Dynamics, Economics & Policy, Washington, DC 20005;; Department of Global Health, University of Washington, Seattle, WA 98104; Princeton Environmental Institute, Princeton University, Princeton, NJ 08544;
11Department of Global Health, University of Washington, Seattle, WA 98104

Tóm tắt

Significance

Antibiotic resistance, driven by antibiotic consumption, is a growing global health threat. Our report on antibiotic use in 76 countries over 16 years provides an up-to-date comprehensive assessment of global trends in antibiotic consumption. We find that the antibiotic consumption rate in low- and middle-income countries (LMICs) has been converging to (and in some countries surpassing) levels typically observed in high-income countries. However, inequities in drug access persist, as many LMICs continue to be burdened with high rates of infectious disease-related mortality and low rates of antibiotic consumption. Our findings emphasize the need for global surveillance of antibiotic consumption to support policies to reduce antibiotic consumption and resistance while providing access to these lifesaving drugs.

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Proceedings of the National Academy of Sciences of the United States of America

Tập 115 Số 15

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