Global Deletion of Ankrd1 Results in a Wound-Healing Phenotype Associated with Dermal Fibroblast Dysfunction

The American Journal of Pathology - Tập 185 - Trang 96-109 - 2015
Susan E. Samaras1, Karinna Almodóvar-García1, Nanjun Wu1, Fang Yu1, Jeffrey M. Davidson1,2
1Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee
2Research Service, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee

Tài liệu tham khảo

Shi, 2005, CARP, a cardiac ankyrin repeat protein, is up-regulated during wound healing and induces angiogenesis in experimental granulation tissue, Am J Pathol, 166, 303, 10.1016/S0002-9440(10)62254-7 Miller, 2003, The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules, J Mol Biol, 333, 951, 10.1016/j.jmb.2003.09.012 Kojic, 2011, Muscle ankyrin repeat proteins: their role in striated muscle function in health and disease, Crit Rev Clin Lab Sci, 48, 269, 10.3109/10408363.2011.643857 Mikhailov, 2008, The enigmatic role of the ankyrin repeat domain 1 gene in heart development and disease, Int J Dev Biol, 52, 811, 10.1387/ijdb.082655am Samaras, 2006, CARP: fishing for novel mechanisms of neovascularization, J Investig Dermatol Symp Proc, 11, 124, 10.1038/sj.jidsymp.5650014 Barash, 2007, Structural and regulatory roles of muscle ankyrin repeat protein family in skeletal muscle, Am J Physiol Cell Physiol, 293, C218, 10.1152/ajpcell.00055.2007 Bang, 2014, The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload, PLoS One, 9, e93638, 10.1371/journal.pone.0093638 Adams, 2005, A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction, Genomics, 86, 753, 10.1016/j.ygeno.2005.08.003 Hayashi, 2003, Maternal inheritance of Cre activity in a Sox2Cre deleter strain, Genesis, 37, 51, 10.1002/gene.10225 Tepper, 2002, Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures, Circulation, 106, 2781, 10.1161/01.CIR.0000039526.42991.93 Normand, 1995, A method for the isolation and serial propagation of keratinocytes, endothelial cells, and fibroblasts from a single punch biopsy of human skin, In Vitro Cell Dev Biol Anim, 31, 447, 10.1007/BF02634257 Chang, 1985, Differential requirement for SV40 early genes in immortalization and transformation of primary rat and human embryonic cells, Virology, 146, 246, 10.1016/0042-6822(85)90008-X Ashby, 2012, Magnetically attachable stencils and the non-destructive analysis of the contribution made by the underlying matrix to cell migration, Biomaterials, 33, 8189, 10.1016/j.biomaterials.2012.07.018 Geback, 2009, TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays, Biotechniques, 46, 265, 10.2144/000113083 Ngo, 2006, Collagen gel contraction assay, Methods Mol Biol, 341, 103 Belgrano, 2011, Multi-tasking role of the mechanosensing protein Ankrd2 in the signaling network of striated muscle, PLoS One, 6, e25519, 10.1371/journal.pone.0025519 Kuo, 1999, Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis, Development, 126, 4223, 10.1242/dev.126.19.4223 Zou, 1997, CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway, Development, 124, 793, 10.1242/dev.124.4.793 Bean, 2014, Ankrd2 is a modulator of NF-kappaB-mediated inflammatory responses during muscle differentiation, Cell Death Dis, 5, e1002, 10.1038/cddis.2013.525 Chen, 2012, Disruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathy, PLoS One, 7, e35743, 10.1371/journal.pone.0035743 Kojic, 2010, A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein, Arch Biochem Biophys, 502, 60, 10.1016/j.abb.2010.06.029 Moulik, 2009, ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene, J Am Coll Cardiol, 54, 325, 10.1016/j.jacc.2009.02.076 Mohamed, 2012, Loss of desmin triggers mechanosensitivity and up-regulation of Ankrd1 expression through Akt-NF-kappaB signaling pathway in smooth muscle cells, FASEB J, 26, 757, 10.1096/fj.10-160291 Arimura, 2009, Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy, J Am Coll Cardiol, 54, 334, 10.1016/j.jacc.2008.12.082 Crocini, 2013, Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue, Basic Res Cardiol, 108, 349, 10.1007/s00395-013-0349-x Duboscq-Bidot, 2009, Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathy, Eur Heart J, 30, 2128, 10.1093/eurheartj/ehp225 Torrado, 2006, Differential atrial versus ventricular ANKRD1 gene expression is oppositely regulated at diastolic heart failure, FEBS Lett, 580, 4182, 10.1016/j.febslet.2006.06.073 Zolk, 2002, Cardiac ankyrin repeat protein, a negative regulator of cardiac gene expression, is augmented in human heart failure, Biochem Biophys Res Commun, 293, 1377, 10.1016/S0006-291X(02)00387-X Matsuura, 2007, Upregulated expression of cardiac ankyrin-repeated protein in renal podocytes is associated with proteinuria severity in lupus nephritis, Hum Pathol, 38, 410, 10.1016/j.humpath.2006.09.006 Scurr, 2008, Ankyrin repeat domain 1, ANKRD1, a novel determinant of cisplatin sensitivity expressed in ovarian cancer, Clin Cancer Res, 14, 6924, 10.1158/1078-0432.CCR-07-5189 Stam, 2007, Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury, Eur J Neurosci, 25, 3629, 10.1111/j.1460-9568.2007.05597.x Langholz, 1995, Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins, J Cell Biol, 131, 1903, 10.1083/jcb.131.6.1903 Ravanti, 1999, Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase, J Biol Chem, 274, 2446, 10.1074/jbc.274.4.2446 Toriseva, 2007, Collagenase-3 (MMP-13) enhances remodeling of three-dimensional collagen and promotes survival of human skin fibroblasts, J Invest Dermatol, 127, 49, 10.1038/sj.jid.5700500 Ballas, 2001, Delayed wound healing in aged rats is associated with increased collagen gel remodeling and contraction by skin fibroblasts, not with differences in apoptotic or myofibroblast cell populations, Wound Repair Regen, 9, 223, 10.1046/j.1524-475x.2001.00223.x Chu, 1995, Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells, J Biol Chem, 270, 10236, 10.1074/jbc.270.17.10236 Boengler, 2003, Arteriogenesis is associated with an induction of the cardiac ankyrin repeat protein (carp), Cardiovasc Res, 59, 573, 10.1016/S0008-6363(03)00511-X de Waard, 2003, Cardiac ankyrin repeat protein (CARP) expression in human and murine atherosclerotic lesions: activin induces CARP in smooth muscle cells, Arterioscler Thromb Vasc Biol, 23, 64, 10.1161/01.ATV.0000042218.13101.50 Kanai, 2001, Transforming growth factor-beta/Smads signaling induces transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscle cells, Circ Res, 88, 30, 10.1161/01.RES.88.1.30 Qin, 2010, Differential alterations in gene expression profiles contribute to time-dependent effects of nandrolone to prevent denervation atrophy, BMC Genomics, 11, 596, 10.1186/1471-2164-11-596 Casey, 2008, Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X, Biomarkers, 13, 364, 10.1080/13547500801903545 Ghosh, 2013, Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis, PLoS One, 8, e63825, 10.1371/journal.pone.0063825 Witt, 2005, Dimerization of the cardiac ankyrin protein CARP: implications for MARP titin-based signaling, J Muscle Res Cell Motil, 26, 401, 10.1007/s10974-005-9022-9 Aragona, 2013, A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors, Cell, 154, 1047, 10.1016/j.cell.2013.07.042 Dupont, 2011, Role of YAP/TAZ in mechanotransduction, Nature, 474, 179, 10.1038/nature10137 Halder, 2012, Transduction of mechanical and cytoskeletal cues by YAP and TAZ, Nat Rev Mol Cell Biol, 13, 591, 10.1038/nrm3416 Piccolo, 2013, Molecular pathways: YAP and TAZ take center stage in organ growth and tumorigenesis, Clin Cancer Res, 19, 4925, 10.1158/1078-0432.CCR-12-3172