Glial Cells and Their Function in the Adult Brain: A Journey through the History of Their Ablation
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Akiyama, 1990, Brain microglia constitutively express beta-2 integrins., J. Neuroimmunol., 30, 81, 10.1016/0165-5728(90)90055-R
Amat, 1996, Phenotypic diversity and kinetics of proliferating microglia and astrocytes following cortical stab wounds., Glia, 16, 368, 10.1002/(SICI)1098-1136(199604)16:4368::AID-GLIA93.0.CO;2-W
Asai, 2015, Depletion of microglia and inhibition of exosome synthesis halt tau propagation., Nat. Neurosci., 18, 1584, 10.1038/nn.4132
Azevedo, 2009, Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain., J. Comp. Neurol., 513, 532, 10.1002/cne.21974
Bardehle, 2013, Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation., Nat. Neurosci., 16, 580, 10.1038/nn.3371
Bergles, 2000, Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus., Nature, 405, 187, 10.1038/35012083
Bessis, 2007, Microglial control of neuronal death and synaptic properties., Glia, 55, 233, 10.1002/glia.20459
Birey, 2015, Age-dependent netrin-1 signaling regulates NG2+ glial cell spatial homeostasis in normal adult gray matter., J. Neurosci., 35, 6946, 10.1523/JNEUROSCI.0356-15.2015
Birey, 2015, Genetic and stress-induced loss of NG2 glia triggers emergence of depressive-like behaviors through reduced secretion of FGF2., Neuron, 88, 941, 10.1016/j.neuron.2015.10.046
Black, 1996, Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy., Proc. Natl. Acad. Sci. U.S.A., 93, 3525, 10.1073/pnas.93.8.3525
Bruttger, 2015, Genetic cell ablation reveals clusters of local self-renewing microglia in the mammalian central nervous system., Immunity, 43, 92, 10.1016/j.immuni.2015.06.012
Buffo, 2008, Origin and progeny of reactive gliosis: a source of multipotent cells in the injured brain., Proc. Natl. Acad. Sci. U.S.A., 105, 3581, 10.1073/pnas.0709002105
Buffo, 2005, Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair., Proc. Natl. Acad. Sci. U.S.A., 102, 18183, 10.1073/pnas.0506535102
Bush, 1999, Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice., Neuron, 23, 297, 10.1016/S0896-6273(00)80781-3
Bush, 1998, Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice., Cell, 93, 189, 10.1016/S0092-8674(00)81571-8
Cahoy, 2008, A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function., J. Neurosci., 28, 264, 10.1523/JNEUROSCI.4178-07.2008
Chari, 2002, Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells., Glia, 37, 307, 10.1002/glia.10038.abs
Chari, 2003, Decline in rate of colonization of oligodendrocyte progenitor cell (OPC)-depleted tissue by adult OPCs with age., J. Neuropathol. Exp. Neurol., 62, 908, 10.1093/jnen/62.9.908
Chitu, 2012, PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts., Blood, 120, 3126, 10.1182/blood-2012-04-425595
Chung, 2013, Generation of demyelination models by targeted ablation of oligodendrocytes in the zebrafish CNS., Mol. Cells, 36, 82, 10.1007/s10059-013-0087-9
Citrin, 2010, Radioprotectors and mitigators of radiation-induced normal tissue injury., Oncologist, 15, 360, 10.1634/theoncologist.2009-S104
Clarke, 1994, Reactive astrocytes express the embryonic intermediate neurofilament nestin., Neuroreport, 5, 1885, 10.1097/00001756-199410000-00011
Cornelis, 2005, Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1., Oncogene, 24, 1552, 10.1038/sj.onc.1208401
Cui, 2001, Inducible ablation of astrocytes shows that these cells are required for neuronal survival in the adult brain., Glia, 34, 272, 10.1002/glia.1061
Davalos, 2005, ATP mediates rapid microglial response to local brain injury in vivo., Nat. Neurosci., 8, 752, 10.1038/nn1472
De Biase, 2010, Excitability and synaptic communication within the oligodendrocyte lineage., J. Neurosci., 30, 3600, 10.1523/JNEUROSCI.6000-09.2010
Dimou, 2014, Glial cells as progenitors and stem cells: new roles in the healthy and diseased brain., Physiol. Rev., 94, 709, 10.1152/physrev.00036.2013
Dimou, 2008, Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex., J. Neurosci., 28, 10434, 10.1523/JNEUROSCI.2831-08.2008
Djogo, 2016, Adult NG2-glia are required for median eminence-mediated leptin sensing and body weight control., Cell Metab., 23, 797, 10.1016/j.cmet.2016.04.013
Doetsch, 1999, Regeneration of a germinal layer in the adult mammalian brain., Proc. Natl. Acad. Sci. U.S.A., 96, 11619, 10.1073/pnas.96.20.11619
Dziennis, 1995, The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice., Blood, 85, k319, 10.1182/blood.V85.2.319.319
Elmore, 2015, Characterizing newly repopulated microglia in the adult mouse: impacts on animal behavior, cell morphology, and neuroinflammation., PLoS ONE, 10, 10.1371/journal.pone.0122912
Elmore, 2014, Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain., Neuron, 82, 380, 10.1016/j.neuron.2014.02.040
Farina, 2007, Astrocytes are active players in cerebral innate immunity., Trends Immunol., 28, 138, 10.1016/j.it.2007.01.005
Faulkner, 2004, Reactive astrocytes protect tissue and preserve function after spinal cord injury., J. Neurosci., 24, 2143, 10.1523/JNEUROSCI.3547-03.2004
ffrench-Constant, 1986, Proliferating bipotential glial progenitor cells in adult rat optic nerve., Nature, 319, 499, 10.1038/319499a0
Fischer, 2005, Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells., Oncogene, 24, 1231, 10.1038/sj.onc.1208290
Fyfe, 1978, Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine., J. Biol. Chem., 253, 8721, 10.1016/S0021-9258(17)34236-9
Geha, 2010, NG2+/Olig2+ cells are the major cycle-related cell population of the adult human normal brain., Brain Pathol., 20, 399, 10.1111/j.1750-3639.2009.00295.x
Geissmann, 2010, Development of monocytes, macrophages, and dendritic cells., Science, 327, 656, 10.1126/science.1178331
Ghosh, 2011, Targeted ablation of oligodendrocytes triggers axonal damage., PLoS ONE, 6, 10.1371/journal.pone.0022735
Gowing, 2008, Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase., J. Neurosci., 28, 10234, 10.1523/JNEUROSCI.3494-08.2008
Gowing, 2006, Mouse model for ablation of proliferating microglia in acute CNS injuries., Glia, 53, 331, 10.1002/glia.20288
Grathwohl, 2009, Formation and maintenance of Alzheimer’s disease beta-amyloid plaques in the absence of microglia., Nat. Neurosci., 12, 1361, 10.1038/nn.2432
Gritsch, 2014, Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice., Nat. Commun., 5, 10.1038/ncomms6472
Hanisch, 2007, Microglia: active sensor and versatile effector cells in the normal and pathologic brain., Nat. Neurosci., 10, 1387, 10.1038/nn1997
Heppner, 2005, Experimental autoimmune encephalomyelitis repressed by microglial paralysis., Nat. Med., 11, 146, 10.1038/nm1177
Herculano-Houzel, 2014, The glia/neuron ratio: how it varies uniformly across brain structures and species and what that means for brain physiology and evolution., Glia, 62, 1377, 10.1002/glia.22683
Hong, 2016a, Complement and microglia mediate early synapse loss in Alzheimer mouse models., Science, 352, 712, 10.1126/science.aad8373
Hong, 2016b, New insights on the role of microglia in synaptic pruning in health and disease., Curr. Opin. Neurobiol., 36, 128, 10.1016/j.conb.2015.12.004
Honjo, 1968, Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis., J. Biol. Chem., 243, 3553, 10.1016/S0021-9258(18)93347-8
Hughes, 2013, Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain., Nat. Neurosci., 16, 668, 10.1038/nn.3390
Irvine, 2007, A different regional response by mouse oligodendrocyte progenitor cells (OPCs) to high-dose X-irradiation has consequences for repopulating OPC-depleted normal tissue., Eur. J. Neurosci., 25, 417, 10.1111/j.1460-9568.2007.05313.x
Jaenisch, 2010, Downregulation of potassium chloride cotransporter KCC2 after transient focal cerebral ischemia., Stroke, 41, e151, 10.1161/STROKEAHA.109.570424
Johnson, 2003, De-intercalation of ethidium bromide and acridine orange by xanthine derivatives and their modulatory effect on anticancer agents: a study of DNA-directed toxicity enlightened by time correlated single photon counting., J. Biomol. Struct. Dyn., 20, 677, 10.1080/07391102.2003.10506884
Ji, 2013, Microglia actively regulate the number of functional synapses., PLoS ONE, 8, 10.1371/journal.pone.0056293
Kalderon, 1996, Severed corticospinal axons recover electrophysiologic control of muscle activity after x-ray therapy in lesioned adult spinal cord., Proc. Natl. Acad. Sci. U.S.A., 93, 11185, 10.1073/pnas.93.20.11185
Karadottir, 2005, NMDA receptors are expressed in oligodendrocytes and activated in ischaemia., Nature, 438, 1162, 10.1038/nature04302
Kaya, 2012, Live imaging of targeted cell ablation in Xenopus: a new model to study demyelination and repair., J. Neurosci., 32, 12885, 10.1523/JNEUROSCI.2252-12.2012
Kessaris, 2006, Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage., Nat. Neurosci., 9, 173, 10.1038/nn1620
Kettenmann, 2005, The Concept of Neuroglia: A Historical Perspective.
Khurgel, 1996, Selective ablation of astrocytes by intracerebral injections of alpha-aminoadipate., Glia, 16, 351, 10.1002/(SICI)1098-1136(199604)16:4351::AID-GLIA73.0.CO;2-2
Kigerl, 2009, Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord., J. Neurosci., 29, 13435, 10.1523/JNEUROSCI.3257-09.2009
Kim, 2016, Brain trauma elicits non-canonical macrophage activation states., J. Neuroinflammation, 13, 10.1186/s12974-016-0581-z
Kimelberg, 2010, Functions of mature mammalian astrocytes: a current view., Neuroscientist, 16, 79, 10.1177/1073858409342593
Kimelberg, 2010, Functions of astrocytes and their potential as therapeutic targets., Neurotherapeutics, 7, 338, 10.1016/j.nurt.2010.07.006
Kipp, 2009, The cuprizone animal model: new insights into an old story., Acta Neuropathol., 118, 723, 10.1007/s00401-009-0591-3
Knox, 1993, The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT)., Cancer Metastasis Rev., 12, 195, 10.1007/BF00689810
Kreutzberg, 1996, Microglia: a sensor for pathological events in the CNS., Trends Neurosci., 19, 312, 10.1016/0166-2236(96)10049-7
Lalancette-Hebert, 2007, Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain., J. Neurosci., 27, 2596, 10.1523/JNEUROSCI.5360-06.2007
Lepore, 2008, Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration., Exp. Neurol., 211, 423, 10.1016/j.expneurol.2008.02.020
Levine, 2001, The oligodendrocyte precursor cell in health and disease., Trends Neurosci., 24, 39, 10.1016/S0166-2236(00)01691-X
Locatelli, 2012, Primary oligodendrocyte death does not elicit anti-CNS immunity., Nat. Neurosci., 15, 543, 10.1038/nn.3062
Loganovsky, 2009, Do low doses of ionizing radiation affect the human brain?, Data Sci. J., 8, 10.2481/dsj.BR-04
May, 2013, Connexin47 protein phosphorylation and stability in oligodendrocytes depend on expression of Connexin43 protein in astrocytes., J. Neurosci., 33, 7985, 10.1523/JNEUROSCI.5874-12.2013
McKenzie, 2014, Motor skill learning requires active central myelination., Science, 346, 318, 10.1126/science.1254960
Miron, 2013, M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination., Nat. Neurosci., 16, 1211, 10.1038/nn.3469
Mirrione, 2010, Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice., Neurobiol. Dis., 39, 85, 10.1016/j.nbd.2010.04.001
Myer, 2006, Essential protective roles of reactive astrocytes in traumatic brain injury., Brain, 129, 2761, 10.1093/brain/awl165
Nave, 2010, Myelination and support of axonal integrity by glia., Nature, 468, 244, 10.1038/nature09614
Nimmerjahn, 2005, Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo., Science, 308, 1314, 10.1126/science.1110647
Nishimura, 2000, Induction of cell death by L-alpha-aminoadipic acid exposure in cultured rat astrocytes: relationship to protein synthesis., Neurotoxicology, 21, 313
Oluich, 2012, Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination., J. Neurosci., 32, 8317, 10.1523/JNEUROSCI.1053-12.2012
Parkhurst, 2013, Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor., Cell, 155, 1596, 10.1016/j.cell.2013.11.030
Pekny, 2014, Astrocyte reactivity and reactive astrogliosis: costs and benefits., Physiol. Rev., 94, 1077, 10.1152/physrev.00041.2013
Pignataro, 2008, Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism., J. Cereb. Blood Flow Metab., 28, 17, 10.1038/sj.jcbfm.9600499
Pineau, 2010, Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion., Brain Behav. Immun., 24, 540, 10.1016/j.bbi.2009.11.007
Praet, 2014, Cellular and molecular neuropathology of the cuprizone mouse model: clinical relevance for multiple sclerosis., Neurosci. Biobehav. Rev., 47, 485, 10.1016/j.neubiorev.2014.10.004
Psachoulia, 2009, Cell cycle dynamics of NG2 cells in the postnatal and ageing brain., Neuron Glia Biol., 5, 57, 10.1017/S1740925X09990354
Ransohoff, 2016, A polarizing question: do M1 and M2 microglia exist?, Nat. Neurosci., 19, 987, 10.1038/nn.4338
Rhodes, 2006, The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines., Neuroscience, 140, 87, 10.1016/j.neuroscience.2006.01.055
Rivers, 2008, PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice., Nat. Neurosci., 11, 1392, 10.1038/nn.2220
Robel, 2011, The stem cell potential of glia: lessons from reactive gliosis., Nat. Rev. Neurosci., 12, 88, 10.1038/nrn2978
Robins, 2013, Extensive regenerative plasticity among adult NG2-glia populations is exclusively based on self-renewal., Glia, 61, 1735, 10.1002/glia.22554
Rodriguez, 2014, Abrogation of β-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury., J. Neurosci., 34, 10285, 10.1523/JNEUROSCI.4915-13.2014
Saffran, 1987, Putative gliotoxin, alpha-aminoadipic acid, fails to kill hippocampal astrocytes in vivo., Neurosci. Lett., 81, 215, 10.1016/0304-3940(87)91001-9
Schneider, 2016, Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells., Glia, 64, 2201, 10.1002/glia.23055
Schreiner, 2015, Astrocyte depletion impairs redox homeostasis and triggers neuronal loss in the adult CNS., Cell Rep., 12, 1377, 10.1016/j.celrep.2015.07.051
Silver, 2015, Central nervous system regenerative failure: role of oligodendrocytes, astrocytes, and microglia., Cold Spring Harb. Perspect. Biol., 7, 10.1101/cshperspect.a020602
Simon, 2011, Progenitors in the adult cerebral cortex: cell cycle properties and regulation by physiological stimuli and injury., Glia, 59, 869, 10.1002/glia.21156
Sirko, 2013, Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected]., Cell Stem Cell, 12, 426, 10.1016/j.stem.2013.01.019
Skripuletz, 2013, Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination., Brain, 136, 147, 10.1093/brain/aws262
Sofroniew, 2015, Astrocyte barriers to neurotoxic inflammation., Nat. Rev. Neurosci., 16, 249, 10.1038/nrn3898
Sofroniew, 2010, Astrocytes: biology and pathology., Acta Neuropathol., 119, 7, 10.1007/s00401-009-0619-8
Szalay, 2016, Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke., Nat. Commun., 7, 10.1038/ncomms11499
Takada, 1986, Fine structural changes in the rat brain after local injections of gliotoxin, alpha-aminoadipic acid., Histol. Histopathol., 1, 271
Takada, 1990, Astroglial ablation prevents MPTP-induced nigrostriatal neuronal death., Brain Res., 509, 55, 10.1016/0006-8993(90)90308-X
Takamiya, 1988, Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats., Brain Res., 466, 201, 10.1016/0165-3806(88)90045-4
Thompson, 2015, Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer., Pain, 156, 1692, 10.1097/j.pain.0000000000000228
Torres, 2016, Dynamic microglial modulation of spatial learning and social behavior., Brain Behav. Immun., 55, 6, 10.1016/j.bbi.2015.09.001
Traka, 2016, Oligodendrocyte death results in immune-mediated CNS demyelination., Nat. Neurosci., 19, 65, 10.1038/nn.4193
Tsai, 2012, Regional astrocyte allocation regulates CNS synaptogenesis and repair., Science, 337, 358, 10.1126/science.1222381
van Rooijen, 1990, Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate., Cell Tissue Res., 260, 215, 10.1007/BF00318625
Vanderluit, 2000, Model for focal demyelination of the spinal dorsal columns of transgenic MBP-LacZ mice by phototargeted ablation of oligodendrocytes., J. Neurosci. Res., 62, 28, 10.1002/1097-4547(20001001)62:128::AID-JNR43.0.CO;2-2
Varnum, 2012, The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer’s disease brain., Arch. Immunol. Ther. Exp., 60, 251, 10.1007/s00005-012-0181-2
Vasek, 2016, A complement-microglial axis drives synapse loss during virus-induced memory impairment., Nature, 534, 538, 10.1038/nature18283
Viganò, 2013, Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain., Nat. Neurosci., 16, 1370, 10.1038/nn.3503
Voskuhl, 2009, Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS., J. Neurosci., 29, 11511, 10.1523/JNEUROSCI.1514-09.2009
Waisman, 2015, Homeostasis of microglia in the adult brain: review of novel microglia depletion systems., Trends Immunol., 36, 625, 10.1016/j.it.2015.08.005
Wang, 2009, Characteristics and functions of NG2 cells in normal brain and neuropathology., Neurol. Res., 31, 144, 10.1179/174313209X393555
Wanner, 2013, Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury., J. Neurosci., 33, 12870, 10.1523/JNEUROSCI.2121-13.2013
Weisser, 2013, Generation and characterization of murine alternatively activated macrophages., Methods Mol. Biol., 946, 225, 10.1007/978-1-62703-128-8_14
Wilhelmsson, 2004, Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration., J. Neurosci., 24, 5016, 10.1523/JNEUROSCI.0820-04.2004
Wu, 2015, Microglia: dynamic mediators of synapse development and plasticity., Trends Immunol., 36, 605, 10.1016/j.it.2015.08.008
Xiao, 2016, Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning., Nat. Neurosci., 19, 1210, 10.1038/nn.4351
Xu, 2007, Turnover of resident retinal microglia in the normal adult mouse., Glia, 55, 1189, 10.1002/glia.20535
Yajima, 1979, Demyelination and remyelination in the rat central nervous system following ethidium bromide injection., Lab. Invest., 41, 385
Young, 2013, Oligodendrocyte dynamics in the healthy adult CNS: evidence for myelin remodeling., Neuron, 77, 873, 10.1016/j.neuron.2013.01.006