Ginsenosides from Korean Red Ginseng ameliorate lung inflammatory responses: inhibition of the MAPKs/NF-κB/c-Fos pathways
Tóm tắt
Từ khóa
Tài liệu tham khảo
Al-Kassimi, 2013, A challenge to the seven widely believed concepts of COPD, Int J Chron Obstruct Pulmon Dis, 8, 21, 10.2147/COPD.S38714
Barnes, 2014, Cellular and molecular mechanisms of chronic obstructive pulmonary disease, Clin Chest Med, 35, 71, 10.1016/j.ccm.2013.10.004
Mulhall, 2015, Phosphodiesterase 4 inhibitors for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs, Expert Opin Investig Drugs, 30, 1
Yonetomi, 2015, Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a Guinea pig model of asthma, Eur J Pharmacol, 765, 242, 10.1016/j.ejphar.2015.08.041
Lee, 2014, Ginsenosides from Korean red ginseng inhibit matrix metalloproteinase-13 expression in articular chondrocytes and prevent cartilage degradation, Eur J Pharmacol, 724, 145, 10.1016/j.ejphar.2013.12.035
Mochizuki, 1995, Inhibitory effect of tumor metastasis in mice by saponins, ginsenosides Rb2, 20(R)- and 20(S)-ginsenoside Rg3, of red ginseng, Biol Pharm Bull, 18, 1197, 10.1248/bpb.18.1197
Nag, 2012, Ginsenosides as anticancer agents: in vitro and in vivo activities, structure-activity relationship, and molecular mechanisms of action, Front Pharmacol, 3, 25, 10.3389/fphar.2012.00025
Wu, 1992, Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine, J Immunol, 148, 1519, 10.4049/jimmunol.148.5.1519
Huh, 1994
Du, 2011, Ginsenoside Rg1, a novel glucocorticoid receptor agonist of plant origin, maintains glucocorticoid efficacy with reduced side effects, J Immunol, 187, 942, 10.4049/jimmunol.1002579
Lee, 2011, Effects of Panax ginseng on tumor necrosis factor-α-mediated inflammation: a mini-review, Molecules, 16, 2802, 10.3390/molecules16042802
Shergis, 2014, Therapeutic potential of Panax ginseng and ginsenosides in the treatment of chronic obstructive pulmonary disease, Complement Ther Med, 22, 944, 10.1016/j.ctim.2014.08.006
Joh, 2011, Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation-the key step of inflammation, Biochem Pharmacol, 82, 278, 10.1016/j.bcp.2011.05.003
Gaffey, 2013, Increased phosphorylated p38 mitogen-activated protein kinase in COPD lungs, Eur Respir J, 42, 28, 10.1183/09031936.00170711
Renda, 2008, Increased activation of p38 MAPK in COPD, Eur Respir J, 31, 62, 10.1183/09031936.00036707
Singh, 2010, A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients, J Clin Pharmacol, 50, 94, 10.1177/0091270009347873
Babayigit, 2008, Ginseng ameliorates chronic histopathologic changes in a murine model of asthma, Allergy Asthma Proc, 29, 493, 10.2500/aap.2008.29.3137
Chen, 2015, Anti-asthmatic effects of ginsenoside Rb1 in a mouse model of allergic asthma through relegating Th1/Th2, Inflammation, 38, 1814, 10.1007/s10753-015-0159-4
Li, 2015, Ginsenoside Rh2 attenuates allergic airway inflammation by modulating nuclear factor-κB activation in a murine model of asthma, Mol Med Rep, 12, 6946, 10.3892/mmr.2015.4272
Kim, 2012, Ginsenoside Rg5 ameliorates lung inflammation in mice by inhibiting the binding of LPS to toll-like receptor-4 on macrophages, Int Immunopharmacol, 12, 110, 10.1016/j.intimp.2011.10.023
Gross, 2002, Ginseng improves pulmonary functions and exercise capacity in patients with COPD, Monaldi Arch Chest Dis, 57, 242
Scaglione, 2001, Effects of the standardized ginseng extract G115 (TM) in patients with chronic bronchitis: a nonblinded, randomized, comparative pilot study, Clin Drug Investig, 21, 41, 10.2165/00044011-200121010-00006
Lee, 2012, Preventive effect of Korean red ginseng for acute respiratory illness: A randomized and double-blind clinical trial, J Korean Med Sci, 27, 1472, 10.3346/jkms.2012.27.12.1472
Shehzad, 2013, State-of-the-art separation of ginsenosides from Korean white and red ginseng by countercurrent chromatography, Anal Bioanal Chem, 405, 4523, 10.1007/s00216-012-6609-z
Chapman, 2007, A novel orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation, J Pharmacol Exp Ther, 322, 486, 10.1124/jpet.106.119040
Lim, 2013, The root barks of Morus alba and the flavonoid constituents inhibit airway inflammation, J Ethnopharmacol, 149, 169, 10.1016/j.jep.2013.06.017
Blackwell, 2000, Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation, Am J Respir Crit Care Med, 162, 1095, 10.1164/ajrccm.162.3.9906129
Lee, 2015, Methyl protodioscin from the roots of Asparagus cochinchinensis attenuates airway inflammation by inhibiting cytokine production, Evid Based Complement Alternat Med, 2015, 640846, 10.1155/2015/640846
Ko, 2011, Inhibition of experimental lung inflammation and bronchitis by phytoformula containing Broussonetia papyrifera and Lonicera japonica, Biomol Ther (Seoul), 19, 324, 10.4062/biomolther.2011.19.3.324
Mosmann, 1983, Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays, J Immunol Methods, 65, 55, 10.1016/0022-1759(83)90303-4
Park, 2005, Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264.7 cells induced by lipopolysaccharide, Biol Pharm Bull, 28, 652, 10.1248/bpb.28.652