Ginsenoside protects intestinal barrier function and improves epithelium injury in sepsis by regulating the miR-30e-5p/FBXO11 axis

Electronic Journal of Biotechnology - Tập 66 - Trang 67-74 - 2023
Wenqian Zhu1, Dingjun Fan2, Zhu Zhou1, Yimei Wang1, Xiang Huang1, Liwen Zhang1, Di Wu1, Yi Ren1, Fei Lu1, Xikun Gao1
1Department of Intensive Care Unit, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu City, Jiangsu Province 210023, China
2Department of Intensive Care Unit, Changshu Guli People’s Hospital, Changshu City, Jiangsu Province 210023, China

Tài liệu tham khảo

Faix, 2013, Biomarkers of sepsis, Crit Rev Clin Lab Sci, 50, 23, 10.3109/10408363.2013.764490 Haussner, 2019, Challenge to the intestinal mucosa during sepsis, Front Immunol, 10, 891, 10.3389/fimmu.2019.00891 Esposito, 2017, Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches, J Glob Antimicrob Resist, 10, 204, 10.1016/j.jgar.2017.06.013 Mancuso, 2017, Panax ginseng and Panax quinquefolius: From pharmacology to toxicology, Food Chem Toxicol, 107, 362, 10.1016/j.fct.2017.07.019 Zhou, 2019, Ginsenoside Rb1 and mitochondria: A short review of the literature, Mol Cell Probes, 43, 1, 10.1016/j.mcp.2018.12.001 Guo, 2022, Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells, J Leukoc Biol, 112, 1065, 10.1002/JLB.1A0422-211R Luo, 2020, Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF-kB/NLRP3 pathway, J Cell Biochem, 121, 2994, 10.1002/jcb.29556 Zhang, 2014, Ginsenoside Rb1 ameliorates lipopolysaccharide-induced albumin leakage from rat mesenteric venules by intervening in both trans- and paracellular pathway, Am J Physiol Gastrointest Liver Physiol, 306, G289, 10.1152/ajpgi.00168.2013 Chen, 2022, Omega-3 fatty acids impair miR-1-3p-dependent Notch3 down-regulation and alleviate sepsis-induced intestinal injury, Mol Med, 28, 9, 10.1186/s10020-021-00425-w Wang, 2019, Ginsenoside Rg1 regulates SIRT1 to ameliorate sepsis-induced lung inflammation and injury via inhibiting endoplasmic reticulum stress and inflammation, Mediators Inflamm, 2019, 6453296 Rowe, 2017, Sepsis in older adults, Infectious DiseasesClin North Am, 31, 731, 10.1016/j.idc.2017.07.010 Yu, 2023, Roles of ginsenosides in sepsis, J Ginseng Res, 47, 1, 10.1016/j.jgr.2022.05.004 Liu, 2020, Discovery and validation of miR-452 as an effective biomarker for acute kidney injury in sepsis, Theranostics, 10, 11963, 10.7150/thno.50093 Li, 2017, Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1-independent autophagy in mice, J Surg Res, 207, 181, 10.1016/j.jss.2016.08.080 Shen, 2021, CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: Potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway, J Neuroinflammation, 18, 246, 10.1186/s12974-021-02300-1 Cao, 2021, Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling, Int Immunopharmacol, 90, 107218, 10.1016/j.intimp.2020.107218 Song, 2022, miR-30e-5p attenuates neuronal deficit and inflammation of rats with intracerebral hemorrhage by regulating TLR4, Exp Ther Med, 24, 492, 10.3892/etm.2022.11419 Cheng, 2021, Resolvin D1 improves the Treg/Th17 imbalance in systemic lupus erythematosus through miR-30e-5p, Front Immunol, 12, 668760, 10.3389/fimmu.2021.668760 Chen, 2021, miR-30e-5p alleviates inflammation and cardiac dysfunction after myocardial infarction through targeting PTEN, Inflammation, 44, 769, 10.1007/s10753-020-01376-w Mei, 2020, Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis, Biomed Pharmacother, 129, 110326, 10.1016/j.biopha.2020.110326 Rye, 2011, FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children, Genes Immun, 12, 352, 10.1038/gene.2011.2 Travis, 2014, TGF-β activation and function in immunity, Annu Rev Immunol, 32, 51, 10.1146/annurev-immunol-032713-120257