Ginsenoside Rg1 of Panax ginseng stimulates the proliferation, odontogenic/osteogenic differentiation and gene expression profiles of human dental pulp stem cells

Phytomedicine - Tập 21 - Trang 177-183 - 2014
Ping Wang1, Xi Wei2, Fujun Zhang3, Kai Yang3, Chen Qu1, Huiqiong Luo1, Longzhu He1
1Department of Stomatology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
2Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou 510055, China
3Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

Tài liệu tham khảo

Attele, 1999, Ginseng pharmacology: multiple constituents and multiple actions, Biochem. Pharmacol., 58, 1685, 10.1016/S0006-2952(99)00212-9 Balloni, 2009, Effects of titanium surface roughness on mesenchymal stem cell commitment and differentiation signaling, Int. J. Oral Maxillofac. Implants, 24, 627 Bluteau, 2008, Stem cells for tooth engineering, Eur. Cell Mater., 31, 1 Brazma, 2001, Minimum information about a microarray experiment (MIAME)-toward standards for microarray data, Nat. Genet., 29, 365, 10.1038/ng1201-365 Chan, 2005, Effects of TGF-betas on the growth collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro, Arch. Oral Biol., 50, 469, 10.1016/j.archoralbio.2004.10.005 Cordeiro, 2008, Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth, J. Endod., 34, 962, 10.1016/j.joen.2008.04.009 Fiorentini, 2011, Effects of osteogenic differentiation inducers on in vitro expanded adult mesenchymal stromal cells, Int. J. Artif. Organs, 34, 998, 10.5301/ijao.5000001 Galler, 2011, Dentin conditioning codetermines cell fate in regenerative endodontics, J. Endod., 37, 1536, 10.1016/j.joen.2011.08.027 Gong, 2006, Effect of 17b-oestradiol and ginsenoside on osteoporosis in ovariectomised rats, J. Asian Nat. Prod. Res., 8, 649, 10.1080/10286020500246063 Gronthos, 2000, Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo, Proc. Natl. Acad. Sci. U S A, 97, 13625, 10.1073/pnas.240309797 Gronthos, 2002, Stem cell properties of human dental pulp stem cells, J. Dent. Res., 81, 531, 10.1177/154405910208100806 Hao, 2004, Differential expression patterns of the dentin matrix proteins during mineralized tissue formation, Bone, 34, 921, 10.1016/j.bone.2004.01.020 He, 2008, Effects of FGF2 and TGFβ on the differentiation of human dental pulp stem cells in vitro, Cell Biol. Int., 32, 827, 10.1016/j.cellbi.2008.03.013 Hung, 2011, A comparison between adipose tissue and dental pulp as sources of MSCs for tooth regeneration, Biomaterials, 32, 6995, 10.1016/j.biomaterials.2011.05.086 Ikeda, 2011, Engineering bone formation from human dental pulp- and periodontal ligament-derived cells, Ann. Biomed. Eng., 39, 26, 10.1007/s10439-010-0115-2 Jittapiromsak, 2010, Acemannan an extracted product from Aloe vera, stimulates dental pulp cell proliferation, differentiation, mineralization, and dentin formation, Tissue Eng. Part A, 16, 1997, 10.1089/ten.tea.2009.0593 Lau, 2008, Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway, J. Steroid Biochem. Mol. Biol., 108, 64, 10.1016/j.jsbmb.2007.06.005 Lee, 2006, TGF-beta2 stimulates cranial suture closure through activation of the Erk-MAPK pathway, J. Cell. Biochem., 98, 981, 10.1002/jcb.20773 Lee, 2010, Effect of calcium phosphate cements on growth and odontoblastic differentiation in human dental pulp cells, J. Endod., 36, 1537, 10.1016/j.joen.2010.04.027 Lu, 2009, Proliferation- and migration-enhancing effects of ginseng and ginsenoside Rg1 through IGF-I- and FGF-2-signaling pathways on RSC96 Schwann cells, Cell Biochem. Funct., 27, 186, 10.1002/cbf.1554 Lu, 2008, Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway, Acta Pharmacol. Sin., 29, 1209, 10.1111/j.1745-7254.2008.00874.x Miura, 2003, SHED: stem cells from human exfoliated deciduous teeth, Proc. Natl. Acad. Sci. U S A, 100, 5807, 10.1073/pnas.0937635100 Nakao, 2004, FGF-2 potently induces both proliferation and DSP expression in collagen type I gel cultures of adult incisor immature pulp cells, Biochem. Biophys. Res. Commun., 325, 1052, 10.1016/j.bbrc.2004.10.136 Nakashima, 2005, The application of tissue engineering to regeneration of pulp and dentin in endodontics, J. Endod., 31, 711, 10.1097/01.don.0000164138.49923.e5 Park, 2009, In vitro osteogenic differentiation of cultured human dental papilla-derived cells, J. Oral Maxillofac. Surg., 67, 507, 10.1016/j.joms.2008.08.037 Renjen, 2009, Root and pulp response after intentional injury from miniscrew placement, Am. J. Orthod. Dentofacial Orthop., 136, 708, 10.1016/j.ajodo.2007.12.031 Saito, 2004, Acceleration effect of human recombinant bone morphogenetic protein-2 on differentiation of human pulp cells into odontoblasts, J. Endod., 30, 205, 10.1097/00004770-200404000-00005 Shen, 2010, Alleviation of ovariectomy-induced osteoporosis in rats by Panax notoginseng saponins, J. Nat. Med., 64, 336, 10.1007/s11418-010-0416-7 Shi, 2009, Ginsenoside Rg1 promotes endothelial progenitor cell migration and proliferation, Acta Pharmacol. Sin., 30, 299, 10.1038/aps.2009.6 Shi, 2003, Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp, J. Bone Miner. Res., 18, 696, 10.1359/jbmr.2003.18.4.696 Suzuki, 2009, Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization, Matrix Biol., 28, 221, 10.1016/j.matbio.2009.03.006 Tsutsumi, 2001, Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF, Biochem. Biophys. Res. Commun., 288, 413, 10.1006/bbrc.2001.5777 Yamada, 2010, A feasibility of useful cell-based therapy by bone regeneration with deciduous tooth stem cells dental pulp stem cells, or bone-marrow-derived mesenchymal stem cells for clinical study using tissue engineering technology, Tissue Eng. Part A, 16, 1891, 10.1089/ten.tea.2009.0732 Yang, 2009, Mineralized tissue formation by BMP2-transfected pulp stem cells, J. Dent. Res., 88, 1020, 10.1177/0022034509346258 Yang, 2008, Non-viral bone morphogenetic protein 2 transfection of rat dental pulp stem cells using calcium phosphate nanoparticles as carriers, Tissue Eng. Part A, 14, 71, 10.1089/ten.a.2007.0102 Yeoh, 2007, Fibroblast growth factors as regulators of stem cell self-renewal and aging, Mech. Ageing Dev., 128, 17, 10.1016/j.mad.2006.11.005 Zhang, 2008, Hard tissue formation in a porous HA/TCP ceramic scaffold loaded with stromal cells derived from dental pulp and bone marrow, Tissue Eng. Part A, 14, 285, 10.1089/tea.2007.0146 Zhou, 2003, Estrogens activate bone morphogenetic protein-2 gene transcription in mouse mesenchymal stem cells, Mol. Endocrinol., 17, 56, 10.1210/me.2002-0210 Zhu, 2009, Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellar calcium homeostasis, J. Cell. Biochem., 108, 117, 10.1002/jcb.22233