Getting the most from venous occlusion plethysmography: proposed methods for the analysis of data with a rest/exercise protocol

Stephen Wythe1, Teifion Davies1, Daniel S. Martin1, Martin Feelisch1, Edward Gilbert‐Kawai1
1University College London Centre for Altitude Space and Extreme Environment Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport and Exercise Health, 170 Tottenham Court Road, London, W1T 7HA, UK

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Hewlett AW, van Zwaluwenburg JG. The rate of blood flow in the arm. Heart. 1909;1:631–46.

Wilkinson IBW, Webb DJ. Venous occlusion plethysmography in cardiovascular research: methodology and clinical applications. Br J Clin Pharmacol. 2001;52:631–46.

Benjamin N, Calver A, Collier J, Robinson B, Vallance P, Webb D. Measuring forearm blood flow and interpreting the responses to drugs and mediators. Hypertension. 1995;25(5):918–23.

Patterson SD, Ferguson RA. Increase in calf post-occlusive blood flow and strength following short-term resistance exercise training with blood flow restriction in young women. Eur J Appl Physiol. 2010;108(5):1025–33.

Aciero PJ, Hannibal NS, Nindl BC, et al. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metab Clin Exp. 2001;50(12):1429–34.

Sinoway LI, Musch TI, Minotti JR, Zelis R. Enhanced maximal metabolic vasodilatation in the dominant forearms of tennis players. J Appl Physiol. 1986;61:673–8.

Chen L-Y, Wang J-S. Effects of intermittent hypoxia on vascular function and hemodynamic control in men. FASEB J. 2006;20:A1255.

Zamudio S, Douglas M, Mazzeo R, et al. Women at altitude: forearm hemodynamics during acclimatization to 4,300 m with a1-adrenergic blockade. Am J Physiol Heart Circ Physiol. 2001;281:H2636–44.

Erzurum SC, Ghosh S, Janocha AJ, Xu W, Bauer S, Bryan NS, et al. Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans. Proc Natl Acad Sci U S A. 2007;104:17593–8.

Martin DS, Gilbert-Kawai ET, Meale PM, et al. Design and conduct of ‘Xtreme Alps’: a double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude. Contemp Clin Trials. 2013;36(2):450–9.

Martin DS, Gilbert-Kawai ET, Levett DZH, et al. Xtreme Everest 2: unlocking the secrets of the Sherpa phenotype? Extreme Physiol Med. 2013;2:30.

Grocott M. Can altitude research benefit critically ill patients? J Intensive Care Soc. 2008;9(1):23–5.

Taylor JA, Chase PB, Enoka RM, et al. Blunted muscle vasodilatation during chemoreceptor stimulation in patients with heart failure. Eur J Appl Physiol Occup Physiol. 1988;58(1–2):32–8.

Preik M, Kelm M, Schafer S, et al. Impairment of adenosine-induced dilation of forearm resistance arteries in patients with arterial hypertension. Vasa. 1997;26(2):70–5.

Beal MD, Jeal S, Bryant J, et al. Modifications of microvascular filtration capacity in human limbs by training and electrical stimulation. Acta Physiol Scand. 2001;173(4):359–68.

Remsburg S, Lanuois SH, Weiss JW. Patients with obstructive sleep apnea have an abnormal peripheral vascular response to hypoxia. J Appl Physiol. 1999;87(3):1148–53.

Nazare Nunes Alves MJ, dos Santos MR, Nobre TS, et al. Mechanisms of blunted muscle vasodilation during peripheral chemoreceptor stimulation in heart failure patients. Hypertension. 2012;60(3):669–76.