Genotoxicity of crude extracts of cyanobacteria from Taihu Lake on carp (Cyprinus carpio)

Qin Wu1, Mei Li1, Xiangyu Gao1, John P. Giesy1, Yibin Cui1, Liuyan Yang1, Zhiming Kong1
1State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Xianlin Campus, 163 Xianlin Avenue, Nanjing, 210046, People’s Republic of China

Tóm tắt

Từ khóa


Tài liệu tham khảo

Al-Sabti K, Metcalfe CD (1995) Fish micronuclei for assessing genotoxicity in water. Mutat Res 343:121–135

Aranda-Rodriguez R, Tillmanns A, Benoit FM, Pick FR, Harvie J, Solenaia L (2005) Pressurized liquid extraction of toxins from cyanobacterial cells. Environ Toxicol 20:390–396

Berg K, Wyman J, Carmichael W, Dabholkar A (1988) Isolated rat liver perfusion studies with cyclic heptapeptide toxins of microcystins and oscillatoria (freshwater cyanobacteria). Toxicon 26:827–837

Binelli A, Cogni D, Parolini M, Riva C, Provini A (2009) Cytotoxic and genotoxic effects of in vitro exposure to triclosan and trimethoprim on zebra mussel (Dreissena polymorpha) hemocytes. Comp Biochem Physiol C 150(1):50–56

Bolognesi C, Perrone E, Roggieri P, Pampanin DM, Sciutto A (2006) Assessment of micronuclei induction in peripheral erythrocytes of fish exposed to xenobiotics under controlled conditions. Aquat Toxicol 78S:S93–S98

Bouaicha N, Maatouk I, Plesis MJ, Périn F (2005) Genotoxic potential of microcystin-LR and nodularin in vitro in primary cultured rat hepatocytes and in vivo in rat liver. Environ Toxicol 20:341–347

Buschini A, Martino A, Gustavino B, Monfrinotti M, Poli P, Santoro M, Dorr AJM, Rizzoni M (2004) Comet assay and micronucleus test in circulating erythrocytes of Cyprinus carpio specimens exposed in situ to lake waters treated with disinfectants for potabilization. Mutat Res 557:119–129

Chen HG, Li ZL, Xu Y, Kong ZM, Liu ZT (2006) DNA damage induced by sodium pentachlorophenate in crucian kidney cells in vivo and in vitro. J Environ Health 23:515–517 (in Chinese)

Chorus I, Bartram J (eds) (1999) Toxic cyanobacteria in water: a guide to their public health consequences, monitoring and management. E and FN Spon; World Health Organization, London; Geneva

Collins A, Dusinska M, Franklin M, Somorovska M, Petrovska H, Duthie S, Fillion L, Panayiotidis M, Raslova K, Vaughan N (1997) Comet assay in human biomonitoring studies: reliability, validation, and applications. Environ Mol Mutagen 30:139–146

Datta S, Saha DR, Ghosh D, Majumdar T, Bhattacharya S, Mazumder S (2007) Sub-lethal concentration of arsenic interferes with the proliferation of hepatocytes and induces in vivo apoptosis in Clarias batrachus L. Comp Biochem Physiol C 145:339–349

Davidson HW, McGowan CH, Balch WE (1992) Evidence for the regulation of exocytic transport by protein phosphorylation. J Cell Biol 116:1343–1355

Dietrich DR, Hoeger SJ (2005) Guidance values for microcystin in water and cyanobacterial supplement products (blue-green algae supplements): a reasonable or misguided approach? Toxicol Appl Pharmacol 203:273–289

Ding WX, Shen HM, Shen Y, Zhu HG, Ong ChN (1998) Microcystic cyanobacteria causes mitochondrial membrane potential alteration and reactive oxygen species formation in primary cultured rat hepatocytes. Environ Health Perspect 106:409–413

Ding WX, Shen HM, Zhu HG, Le BL, Ong ChN (1999) Genotoxicity of microcystic cyanobacteria extract of a water source in China. Mutat Res 442:69–77

Djediat C, Malecot M, Luze A, Bernard C, Dao SP, Edery M (2010) Localization of microcystin-LR in medaka fish tissues after cyanotoxin gavage. Toxicon 55:531–535

Fawell JK, Mitchell RE, Everett DJ, Hill RE (1999) The toxicity of cyanobacterial toxins in the mouse: I microcystin-LR. Hum Exp Toxicol 18:162–167

Fenech M, Chang WP, Kirsch VM, Holland N, Bonassi S, Zeiger E (2003) HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res 534:65–75

Fischer WJ, Altheimer S, Cattori V, Meier PJ, Dietrich DR, Hagenbuch B (2005) Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin. Toxicol Appl Pharmacol 203:257–263

Gaudin J, Huet S, Jarry G, Fessard V (2008) In vivo DNA damage induced by the cyanotoxin microcystin-LR: comparison of intra-peritoneal and oral administrations by use of the comet assay. Mutat Res 652:65–71

Gérard C, Poullain V, Lance E, Acou A, Brient L, Carpentier A (2009) Influence of toxic cyanobacteria on community structure and microcystin accumulation of freshwater mollusks. Environ Pollut 157:609–617

Gulland FM, Fauquier D, Langlois G, Lander ME, Zabka T, Duerr R (2002) Domoic acid toxicity in Californian sea lions (Zalophus californianus): clinical signs, treatment and survival. Vet Rec 150:475–480

Harada KI, Suzuki M, Dhalem AM, Beasly VR, Carmichael WW, Rinehart KL (1988) Improved method for purification of toxic peptides produced by cyanobacteria. Toxicon 26:433–439

Heddle JA, Cimino MC, Hayashi M, Romagna F, Shelby MD, Tucker JD, Vanparys P, MacGregor JT (1991) Micronuclei as an index of cytogenetic damage: past, present, and future. Environ Mol Mutagen 18:277–291

Hicks SW, Machamer CE (2005) Golgi structure in stress sensing and apoptosis. Biochim Biophys Acta 1744:406–414

Hoeger SJ, Hitzfeld BC, Dietrich DR (2005) Occurrence and elimination of cyanobacterial toxins in drinking water treatment plants. Toxicol Appl Pharmacol 203:231–242

Humpage AR, Fenech M, Thomas P, Falconer IR (2000) Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mutat Res 472:155–161

Lakshmana Rao PV, Bhattacharya R, Parida MM, Jana AM, Bhaskar ASB (1998) Freshwater cyanobacterium Microcystis aeruginosa (UTEX 2385) induced DNA damage in vivo and in vitro. Environ Toxicol Pharmacol 5:1–6

Lance E, Josso C, Dietrich D, Ernst B, Paty C, Senger F, Bormans M, Gérard C (2010) Histopathology and microcystin distribution in Lymnaea stagnalis (Gastropoda) following toxic cyanobacterial or dissolved microcystin-LR exposure. Aquat Toxicol 98:211–220

Lankoff A, Banasik A, Obe G, Deperas M, Kuzminski K, Tarzynska M, Jurczak T, Wojcik A (2003) Effect of microcystin-LR and cyanobacterial extract from Polish reservoir of drinking water on cell cycle progression, mitotic spindle, and apoptosis in CHO-K1 cells. Toxicol Appl Pharmacol 189:204–213

Lankoff A, Krzowski L, Glab J, Banasik A, Lisowska H, Kuszewski T, Gozdz S, Wojcik A (2004) DNA damage and repair in human peripheral blood lymphocytes following treatment with microcystin-LR. Mutat Res 559:131–142

Lankoff A, Wojcik A, Fessard V, Meriluoto J (2006) Nodularin-induced genotoxicity following oxidative DNA damage and aneuploidy in HepG2 cells. Toxicol Lett 164:239–248

Li XY, Liu YD, Song LR (2001) Cytological alterations in isolated hepatocytes from common carp (Cyprinus carpio L.) exposed to microcystin-LR. Environ Toxicol 16:517–522

Li YQ, Sun LW, Qu MM, Kong ZM, Liu ZT (2004) In vivo genotoxic effects of aminophenols in carp (Cyprinus caprio) kidney cells. Res Environ Sci 17:35–37 (in Chinese)

Lovell DP, Omori T (2008) Statistical issues in the use of the comet assay. Mutagenesis 23:171–182

Maag RS, Hicks SW, Machamer CE (2003) Death from within: apoptosis and the secretory pathway. Curr Opin Cell Biol 15:456–461

Maatouk I, Bouaicha N, Plessis MJ, Perin F (2004) Detection by 32P-postlabelling of 8-oxo-7,8-dihydro-2-deoxyguanosine in DNA as biomarker of microcystin-LR- and nodularin-induced DNA damage in vitro in primary cultured rat hepatocytes and in vivo in rat liver. Mutat Res 564:9–20

Mankiewicz J, Walter Z, Tarczynska Z, Palyvoda O, Wojtysiak SM, Zalewski M (2002) Genotoxicity of cyanobacterial extracts containing microcystins from Polish water reservoirs as determined by SOS chromotest and comet assay. Environ Toxicol 17:341–350

Mitchelmore CL, Chipman JK (1998) DNA strand breakage in aquatic organisms and the potential values of the comet assay in environmental monitoring. Mutat Res 399:135–147

Morel FMM, Price NM (2003) The biogeochemical cycles of trace metals in the oceans. Science 300:944–947

Paerl HW, Fulton R, Moisander PH, Dyble J (2001) Harmful freshwater algal blooms, with an emphasis on cyanobacteria. Sci World 1:76–113

Puschner B, Galey FD, Johnson B, Dickie CW, Vondy M, Francis T, Holstege DM (1998) Blue-green algae toxicosis in cattle. J Am Vet Med Assoc 213(11):1605–1607

Qi LL, Chen ZB, Zou H, Ruan WQ (2009) HPLC determination of microcystin in Taihu Lake. J Food Sci Biotechnol 28(1):97–101 (in Chinese)

Rao PVL, Bhattacharya R (1996) The cyanobacterial toxin microcystin-LR induced DNA damage in mouse liver in vivo. Toxicology 114:29–36

Ross C, Santiago VL, Paul V (2006) Toxin release in response to oxidative stress and programmed cell death in the cyanobacterium Microcystis aeruginosa. Aquat Toxicol 78:66–73

Runnegar M, Berndt N, Kong SM, Lee EYC, Zhang LF (1995) In vivo and in vitro binding of microcystin to protein phosphatase 1 and 2A. Biochem Biophys Res Commun 216:162–169

Schnetzer A, Miller PE, Schaffner RA, Stauffer BA, Jones BH, Weisberg SB, DiGiacomo PM, Berelson WM, Caron DA (2007) Blooms of Pseudo-nitzschia and domoic acid in the San Pedro Channel and Los Angeles harbor areas of the Southern California Bight, 2003–2004. Harmful Algae 6:372–387

Shen X, Lam PKS, Shaw GR, Wickramasinghe W (2002) Genotoxicity investigation of a cyanobacterial toxin, cylindrospermopsin. Short Commun Toxicon 40:1499–1501

Shumway SE, Allen SM, Boersma PD (2003) Marine birds and harmful algal blooms: sporadic victims or under-reported events? Harmful Algae 2:1–17

Sournia A, Chrdtiennot-Dinet MJ, Ricard M (1991) Marine phytoplankton: how many species in the world ocean? J Plankton Res 13:1093–1099

Steinert SA (1999) DNA damage as bivalve biomarker and as an environmental assessment tool. Biomarkers 4:492–496

Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Rojas E, Miyamae Y, Ryu JC, Sasaki YF (2000) Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35:206–221

Xu QJ, Chen WM, Gao G (2008) Seasonal variations in microcystin concentrations in Lake Taihu, China. Environ Monit Assess 145:75–79

Yu SJ (1995) Primary prevention of hepatocellular carcinoma. J Gastroenterol Hepatol 10:674–682

Zegura B, Sedmak B, Filipic M (2003) Microcystin-LR induces oxidative DNA damage in human hepatoma cell line HepG2. Toxicon 41:41–48

Zhan L, Sakamoto H, Sakuraba M, Wu DS, Zhang LS, Suzuki T, Hayashi M, Honma M (2004) Genotoxicity of microcystin-LR in human lymphoblastoid TK6 cells. Mutat Res 557:1–6

Zhu Y, Wang J, Zhang R (2004) Cadmium, chromium, and copper induce polychromatocyte micronuclei in Carp (Cyprinus carpio L.). Bull Environ Contam Toxicol 72:78–86