Genotoxic activity in vivo of the naturally occurring glucoside, cycasin, in the Drosophila wing spot test

Mutation Research Letters - Tập 346 - Trang 145-149 - 1995
Kazuaki Kawai1, Hideyuki Furukawa1, Iwao Hirono2
1Faculty of Pharmaceutical Sciences, Meijo University, Yagotoyama 150, Tempaku-ku, Nagoya 468, Japan
2Department of Pathology, Fujita-Gakuen Health University School of Medicine, I-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-11, Japan

Tài liệu tham khảo

Becker, 1976, Mitotic recombination, Vol. 1C, 1020 Brown, 1979, Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test. Activation of flavonol glycosides by mixed glucosidases from rat cecal bacteria and other sources, Mutation Res., 66, 223, 10.1016/0165-1218(79)90083-1 Frei, 1988, Statistical methods to decide whether mutagenicity test data from Drosophila assay indicate a positive, negative or inconclusive result, Mutation Res., 203, 297, 10.1016/0165-1161(88)90019-2 Garcia-Bellido, 1974, Induction, detection and characterization of cell differentiation mutatns in Drosophila, Mol. Gen. Genet., 128, 117, 10.1007/BF02654485 Graf, 1984, Somatic mutation and recombination test in Drosophila melanogaster, Environ. Mutagen., 6, 153, 10.1002/em.2860060206 Haynie, 1977, The effects of X-rays on the proliferation dynamics in the imaginal wing disc of Drosophila melanogaster, Wilhelm Roux' Arch., 183, 85, 10.1007/BF00848779 Kandler, 1986, Regular nonsporing Grampositive rods, Vol. 2, 1208 Matsushima, 1979, Mutagenicity of the naturally occurring carcinogen cycasin and synthetic methylazoxymethanol conjugates in Salmonella typhimurium, Cancer Res., 39, 3780 Nishida, 1955, Cycasin, a new toxic glycoside of Cycas revoluta Thunb. 1. Isolation and structure of cycasin, Bull. Agric. Chem. Soc. Jpn., 19, 77, 10.1271/bbb1924.19.77 Smith, 1966, Mutagenicity of cycasin aglycone (methylazoxymethanol), a naturally occurring carcinogen, Science, 152, 1273, 10.1126/science.152.3726.1273 Spatz, 1966, Cycasin excretion in conventional and germfree rats, 125, 988 Tamura, 1988, Fecalase: A model for activation of dietary glyucosides to mutagens by intestinal flora, 77, 4961 Teas, 1967, Mutation in Drosophila by methylazoxymethanol, the aglycone of cycasin, 125, 988