Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

Cover, T. L. & Blaser, M. J. Helicobacter pylori and gastroduodenal disease. Annu. Rev. Med. 42, 135– 145 (1992).

Atherton, J. C. J, Peek, R. M. J, tham, K. T., Cover, T. L. & Blaser, M. J. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 12, 92– 99 (1997).

Blaser, M. J. Not all Helicobacter pylori strains are created equal: should all be eliminated? Lancet 349, 1020– 1022 (1997).

Logan, R. P. H. & Berg, D. E. Genetic diversity of Helicobacter pylori. Lancet 348 1462–1463 (1996).

Tomb, J.-F. The complete genome sequence of the gastric pathogen Helicobacter pylori . Nature 388, 539–547 (1997).

Curnow, A. W. et al. Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation. Proc. Natl Acad. Sci. USA 94, 11819– 11826 (1997).

Akopyants, N. S. et al. Analyses of the cag pathogenicity island of Helicobacter pylori. Mol. Microbiol. 28, 37– 53 (1998).

Censini, S. et al. cag, a pathogenecity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc. Natl Acad. Sci. USA 93, 14648– 14653 (1996).

Akopyanz, N., Bukanov, N. O., Westblom, T. U. & Berg, D. E. PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogen Helicobacter pylori. Nucleic Acids Res. 20, 6221–6225 (1992).

Han, J., Yu, E., Lee, I. & Lee, Y. Diversity among clinical isolates of Helicobacter pylori in Korea. Mol. Cells 7, 544–547 (1997).

Kansau, I. et al. Genotyping of Helicobacter pylori isolates by sequencing of PCR products and comparison with the RAPD technique. Res. Microbiol. 147, 661–669 ( 1996).

Ilver, D. et al. Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging. Science 279, 373–377 (1998).

Lee, W. K. et al. Construction of a Helicobacter pylori–Escherichia coli shuttle vector for gene transfer in Helicobacter pylori. Appl. Environ. Microbiol. 63, 4866– 4871 (1997).

Jiang, Q., Hiratsuka, K. & Taylor, D. E. Variability of gene order in different Helicobacter pylori strains contributes to genome diversity. Mol. Microbiol. 20, 833–842 ( 1996).

Suerbaum, S., Brauer-Steppkes, T., Labigne, A., Cameron, B. & Drlica, K. Topoisomerase I of Helicobacter pylori: juxtaposition with a flagellin gene (flaB) and functional requriement of a fourth zinc finger motif. Gene 210 , 151–161 (1998).

Tatusov, R. L. et al. Metabolism and evolution of Haemophilus influenzae deduced from a whole-genome comparison with Escherichia coli. Curr. Biol. 6, 279–291 ( 1996).

Saunders, N. J., Peden, J. F., Hood, D. w. & Moxon, E. R. Simple sequence repeats in the Helicobacter pylori genome. Mol. Microbiol. 27, 1091–1098 (1998).

Sakagami, T. et al. Atrophic gastrities changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis. Gut 39, 639– 648 (1996).

Fock, K. M. et al. Seroprevalence of Helicobacter pylori infection. Gastroenterology 114, A596 (1998 ).

Smith, D. R. Complete genome sequence of Methanobacetrium thermoautotrophicum deltaH: functional analysis and comparative genomics. J. Bacteriol. 179, 7135–7155 (1997).