Genome-wide pathway analysis of memory impairment in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

Springer Science and Business Media LLC - Tập 6 Số 4 - Trang 634-648 - 2012
Vijay K. Ramanan1, Sungeun Kim2, Kelly Holohan3, Li Shen2, Kwangsik Nho2, Shannon L. Risacher2, Tatiana Foroud3, Shubhabrata Mukherjee4, Paul K. Crane4, Paul S. Aisen5, Ronald C. Petersen6, Michael W. Weiner7,8, Andrew J. Saykin9
1Medical Scientist Training Program, Indiana University School of Medicine, Indianapolis, USA
2Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, USA
3Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, USA
4University of Washington
5Department of Neurosciences, University of California San Diego, San Diego, USA
6Department of Neurology, Mayo Clinic-Minnesota, Rochester, USA
7Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, San Francisco, USA
8Departments of Radiology, Medicine and Psychiatry, University of California, San Francisco, San Francisco, USA
9Department of Medical and Molecular Genetics, Indiana University, School of Medicine, Indianapolis, USA

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