Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
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Hirschhorn, J. N. & Daly, M. J. Genome-wide association studies for common diseases and complex traits. Nature Rev. Genet. 6, 95–108 (2005)
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661–678 (2007)
Koornneef, M., Alonso-Blanco, C. & Vreugdenhil, D. Naturally occurring genetic variation in Arabidopsis thaliana . Annu. Rev. Plant Biol. 55, 141–172 (2004)
Shindo, C. et al. Role of FRIGIDA and FLC in determining variation in flowering time of Arabidopsis thaliana . Plant Physiol. 138, 1163–1173 (2005)
Kim, S. et al. Recombination and linkage disequilibrium in Arabidopsis thaliana . Nature Genet. 39, 1151–1155 (2007)
Nordborg, M. et al. The extent of linkage disequilibrium in Arabidopsis thaliana . Nature Genet. 30, 190–193 (2002)
Aranzana, M. J. et al. Genome-wide association mapping in Arabidopsis identifies previously known flowering time and pathogen resistance genes. PLoS Genet. 1, e60 (2005)
Zhao, K. et al. An Arabidopsis example of association mapping in structured samples. PLoS Genet. 3, e4 (2007)
Pritchard, J. K., Stephens, M., Rosenberg, N. A. & Donnelly, P. Association mapping in structured populations. Am. J. Hum. Genet. 67, 170–181 (2000)
Price, A. L. et al. Principal components analysis corrects for stratification in genome-wide association studies. Nature Genet. 38, 904–909 (2006)
Yu, J. et al. A unified mixed-model method for association mapping that accounts for multiple levels of relatedness. Nature Genet. 38, 203–208 (2005)
Kang, H. M. et al. Efficient control of population structure in model organism association mapping. Genetics 178, 1709–1723 (2008)
Grant, M. R. et al. Structure of the Arabidopsis RPM1 gene enabling dual-specificity disease resistance. Science 269, 843–846 (1995)
Johanson, U. et al. Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time. Science 290, 344–347 (2000)
Toomajian, C. et al. A non-parametric test reveals selection for rapid flowering in the Arabidopsis genome. PLoS Biol. 4, e137 (2006)
Michaels, S. D. & Amasino, R. M. FLOWERING LOCUS C encodes a novel MADS domain protein that acts as a repressor of flowering. Plant Cell 11, 949–956 (1999)
Bentsink, L., Jowett, J., Hanhart, C. J. & Koornneef, M. Cloning of DOG1, a quantitative trait locus controlling seed dormancy in Arabidopsis . Proc. Natl Acad. Sci. USA 103, 17042–17047 (2006)
Rus, A. et al. Natural variants of AtHKT1 enhance Na+ accumulation in two wild populations of Arabidopsis . PLoS Genet. 2, e210 (2006)
Baxter, I. et al. Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1). PLoS Genet. 4, e1000004 (2008)
Hilscher, J., Schlötterer, C. & Hauser, M.-T. A single amino acid replacement in ETC2 acts as major modifier of trichome patterning in natural Arabidopsis populations. Curr. Biol. 19, 1747–1751 (2009)
Lu, H., Rate, D. N., Song, J. T. & Greenberg, J. T. ACD6, a novel ankyrin protein, is a regulator and an effector of salicylic acid signaling in the Arabidopsis defense response. Plant Cell 15, 2408–2420 (2003)
Manolio, T. A. et al. Finding the missing heritability of complex diseases. Nature 461, 747–753 (2009)
Han, J. et al. A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet. 4, e1000074 (2008)
Stokowski, R. P. et al. A genomewide association study of skin pigmentation in a South Asian population. Am. J. Hum. Genet. 81, 1119–1132 (2007)
Rosenberg, N. A. & Nordborg, M. A general population-genetic model for the production by population structure of spurious genotype-phenotype associations in discrete, admixed, or spatially distributed populations. Genetics 173, 1665–1678 (2006)