Genetics of cellular senescence

Mechanisms of Ageing and Development - Tập 123 - Trang 927-936 - 2002
Kaoru Tominaga1,2, Abdullah Olgun3, James R. Smith1,4, Olivia M. Pereira-Smith1,2
1Sam and Ann Barshop Center for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, STCBM, 15355 Lambda Drive, San Antonio, TX 78245-3207, USA
2Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, STCBM, 15355 Lambda Drive, San Antonio, TX 78245-3207, USA
3Department of Biochemistry and Clinical Biochemistry, Gulhane School of Medicine, Etlik, 06018 Ankara, Turkey
4Department of Pathology, University of Texas Health Science Center at San Antonio, STCBM, 15355 Lambda Drive, San Antonio, TX 78245-3207, USA

Tài liệu tham khảo

Acquati, 2001, Cloning and chracterization of a senescence inducing and class II tumor suppressor gene in ovarian carcinoma at chromosome region 6q27, Oncogene, 20, 980, 10.1038/sj.onc.1204178 Allsopp, 1992, Telomere length predicts replicative capacity of human fibroblasts, Proc. Natl. Acad. Sci. USA, 89, 10114, 10.1073/pnas.89.21.10114 Backsch, 2001, Microcell-mediated transfer of chromosome 4 into HeLa cells suppresses telomerase activity, Genes Chromosomes Cancer, 31, 196, 10.1002/gcc.1134 Banga, 1997, SEN6, a locus for SV40-mediated immortalization of human cells, maps to 6q26-27, Oncogene, 14, 313, 10.1038/sj.onc.1200842 Bertram, 1999, Assembly of BAC contig of the complementation group B cell senescence gene candidate region at 4q33-q34.1 and identification of expressed sequences, Genomics, 56, 353, 10.1006/geno.1998.5726 Bertram, 1999, Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes, Mol. Cell. Biol., 19, 1479, 10.1128/MCB.19.2.1479 Bertram, 2001, Conservation of the MORF4 related gene family: identification of a new chromo domain subfamily and novel protein motif, Gene, 266, 111, 10.1016/S0378-1119(01)00372-9 Bodnar, 1998, Extension of life span by introduction of telomerase into normal human cells, Science, 279, 349, 10.1126/science.279.5349.349 Brown, 1997, Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts, Science, 277, 831, 10.1126/science.277.5327.831 Bryan, 1997, Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines, Nature Med., 3, 1271, 10.1038/nm1197-1271 Bryan, 1995, Telomere elongation in immortal human cells without detectable telomerase activity, EMBO J., 14, 4240, 10.1002/j.1460-2075.1995.tb00098.x Bryan, 1997, Telomere dynamics and telomerase activity in in vitro immortalised human cells, Eur. J. Cancer, 33A, 767, 10.1016/S0959-8049(97)00065-8 Campisi, 2001, Cellular senescence as a tumor-suppressor mechanism, Trends Cell Biol., 11, S27, 10.1016/S0962-8924(01)82148-6 Carrel, 1912, On the permanent life of tissues outside of the organism, J. Exp. Med., 15, 516, 10.1084/jem.15.5.516 Cavalli, 1998, Chromo-domain proteins: linking chromatin structure to epigenetic regulation, Curr. Opin. Cell Biol., 10, 354, 10.1016/S0955-0674(98)80011-2 Cuthbert, 1999, Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells, J. Natl. Cancer Inst., 91, 37, 10.1093/jnci/91.1.37 Dimri, 1995, A biomarker that identifies senescent human cells in culture and in aging skin in vivo, Proc. Natl. Acad. Sci. USA, 92, 9363, 10.1073/pnas.92.20.9363 Ducrest, 2001, Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity, Cancer Res., 61, 7594 Duncan, 1993, Assignment of SV40-immortalized cells to more than one complementation group for immortalization, Exp. Cell Res., 205, 337, 10.1006/excr.1993.1095 Eisen, 2001, The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation, J. Biol. Chem., 276, 3484, 10.1074/jbc.M008159200 Goletz, 1994, Genetic analysis of indefinite division in human cells: evidence for a common immortalizing mechanism in T and B lymphoid cell lines, Exp. Cell Res., 215, 82, 10.1006/excr.1994.1318 Greenberg, 1999, Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation, Oncogene, 18, 1219, 10.1038/sj.onc.1202669 Hara, 1996, Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence, Mol. Cell. Biol., 16, 567, 10.1128/MCB.16.3.859 Harley, 1990, Telomeres shorten during ageing of human fibroblasts, Nature, 345, 458, 10.1038/345458a0 Hayflick, 1965, The limited in vitro lifetime of human diploid cell strains, Exp. Cell Res., 37, 614, 10.1016/0014-4827(65)90211-9 Hayflick, 1961, The serial cultivation of human diploid cell strains, Exp. Cell Res., 25, 585, 10.1016/0014-4827(61)90192-6 Hensler, 1994, A gene involved in control of human cellular senescence on human chromosome 1q, Mol. Cell. Biol., 14, 2291, 10.1128/MCB.14.4.2291 Horikawa, 1998, Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence, Mol. Carcinog., 22, 65, 10.1002/(SICI)1098-2744(199806)22:2<65::AID-MC1>3.0.CO;2-J Hunt, 1996, Evaluation of phenotypic alteration by microcell-mediated chromosome transfer, Anal. Biochem., 238, 107, 10.1006/abio.1996.0263 Jones, 2000, Mammalian chromodomain proteins: their role in genome organisation and expression, BioEssays, 22, 124, 10.1002/(SICI)1521-1878(200002)22:2<124::AID-BIES4>3.0.CO;2-E Julicher, 1999, Novel tumor suppressor locus in human chromosome region 3p14.2, J. Natl. Cancer Inst., 91, 1563, 10.1093/jnci/91.18.1563 Kim, 1994, Specific association of human telomerase activity with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428 Klein, 1991, Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control, Science, 251, 796, 10.1126/science.1990442 Koi, 1993, Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11, Science, 260, 361, 10.1126/science.8469989 Koonin, 1995, The chromo superfamily: new members, duplication of the chromodomain and possible role in delivering transcription regulators to chromatin, Nucleic Acids Res., 23, 4229, 10.1093/nar/23.21.4229 Krtolica, 2001, Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging, Proc. Natl. Acad. Sci. USA, 98, 12072, 10.1073/pnas.211053698 Kugoh, 2000, Cellular senescence of human bladder carcinoma cell line (JTC-32) induced by a normal chromosome 11, Cancer Genet. Cytogenet., 116, 158, 10.1016/S0165-4608(99)00138-7 Leung, 2001, MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14, J. Biol. Chem., 276, 39171, 10.1074/jbc.M103435200 Ly, 2000, Mitotic misregulation and human aging, Science, 287, 2486, 10.1126/science.287.5462.2486 Morelli, 2000, Cloning and characterization of two overlapping genes in a subregion at 6q21 involved in replicative senescence and schizophrenia, Gene, 252, 217, 10.1016/S0378-1119(00)00231-6 Nakabayashi, 1997, Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1, Exp. Cell Res., 235, 345, 10.1006/excr.1997.3678 Nakabayashi, 1999, Introduction of chromosome 7 suppresses telomerase with shortening of telomeres in human mesothelial cell line, Exp. Cell Res., 252, 376, 10.1006/excr.1999.4619 Nakayama, 1998, Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas, Nat. Genet., 18, 65, 10.1038/ng0198-65 Ning, 1991, Tumor suppression by chromosome 11 is not due to cellular senescence, Exp. Cell Res., 192, 220, 10.1016/0014-4827(91)90179-X Ning, 1991, Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4, Proc. Natl. Acad. Sci. USA, 88, 5635, 10.1073/pnas.88.13.5635 Noda, 1994, Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen, Exp. Cell Res., 211, 90, 10.1006/excr.1994.1063 Ogata, 1993, Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1, Mol. Cell. Biol., 13, 6036, 10.1128/MCB.13.10.6036 Ogata, 1995, Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7, Jpn. J. Cancer Res., 86, 35, 10.1111/j.1349-7006.1995.tb02985.x Ohmura, 1995, Restoration of the cellular senescence program and repression of telomerase by human chromosome 3, Jpn. J. Cancer Res., 86, 899, 10.1111/j.1349-7006.1995.tb02998.x Pereira-Smith, 1990, Hybrids from fusion of normal human T lymphocytes with immortal human cells exhibit limited life span, J. Cell. Physiol., 144, 546, 10.1002/jcp.1041440324 Pereira-Smith, 1983, Evidence for the recessive nature of cellular immortality, Science, 221, 964, 10.1126/science.6879195 Pereira-Smith, 1988, Genetic analysis of indefinite division in human cells: identification of four complementation groups, Proc. Natl. Acad. Sci. USA, 85, 6042, 10.1073/pnas.85.16.6042 Poignee, 2001, Evidence for a putative senescence gene locus within the chromosomal region 10p14–p15, Cancer Res., 61, 7118 Reddy, 1999, Identification of a gene at 16q24.3 that restores cellular senescence in immortal mammary tumor cells, Oncogene, 18, 5100, 10.1038/sj.onc.1202888 Sandhu, 1994, Senescence of immortal human fibroblasts by the introduction of normal human chromosome 6, Proc. Natl. Acad. Sci. USA, 91, 5498, 10.1073/pnas.91.12.5498 Sandhu, 1996, A gene on 6q14-21 restores senescence to immortal ovarian tumor cells, Oncogene, 12, 247 Sasaki, 1994, Evidence for multiple pathways to cellular senescence, Cancer Res., 54, 6090 Smith, 1996, Replicative senescence: implications for in vivo aging and tumor suppression, Science, 273, 63, 10.1126/science.273.5271.63 Steenbergen, 2001, Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized kerationcyte cell line and in a cervical cancer cell line, J. Natl. Cancer Inst., 93, 865, 10.1093/jnci/93.11.865 Sugawara, 1990, Induction of cellular senescence in immortalized cells by human chromosome 1, Science, 247, 707, 10.1126/science.2300822 Tanaka, 1999, Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer, Mol. Carcinog., 25, 249, 10.1002/(SICI)1098-2744(199908)25:4<249::AID-MC3>3.0.CO;2-Z Tanaka, 1998, Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region, Genes Chromosomes Cancer, 23, 123, 10.1002/(SICI)1098-2264(199810)23:2<123::AID-GCC5>3.0.CO;2-4 Uejima, 1995, Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa, Genes Chromosomes Cancer, 14, 120, 10.1002/gcc.2870140206 Uejima, 1998, Mapping a novel cellular-senescence gene to human chromosome 2q37 by irradiation microcell-mediated chromosome transfer, Mol. Carcinog., 22, 34, 10.1002/(SICI)1098-2744(199805)22:1<34::AID-MC5>3.0.CO;2-L Vaziri, 1998, Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span, Curr. Biol., 8, 279, 10.1016/S0960-9822(98)70109-5 Wadhwa, 1993, Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts, Exp. Cell Res., 207, 442, 10.1006/excr.1993.1213 Wang, 1998, Myc activates telomerase, Genes Dev., 12, 1769, 10.1101/gad.12.12.1769 Wei, 1999, Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts, Cancer Res., 59, 1539 Whitaker, 1992, Finite life span of hybrids formed by fusion of different simian virus 40-immortalized human cell lines, J. Virol., 66, 1202, 10.1128/JVI.66.2.1202-1206.1992 Wu, 1999, Direct activation of TERT transcription by c-MYC, Nat. Genet., 21, 220, 10.1038/6010 Yang, 1999, Human endothelial cell life extension by telomerase expression, J. Biol. Chem., 274, 26141, 10.1074/jbc.274.37.26141 Yang, 1999, Functional roles of chromosomes 11 and 17 in the transformation of human breast epithelial cells in vitro, Int. J. Oncol., 15, 629