Genetic variants in antioxidant pathway: Risk factors for hepatotoxicity in tuberculosis patients

Tuberculosis - Tập 92 - Trang 253-259 - 2012
Kazutaka Nanashima1, Tsutomu Mawatari1, Naoko Tahara1, Norihide Higuchi2, Ayano Nakaura1, Tatsuo Inamine1, Shinji Kondo1, Katsunori Yanagihara3, Kiyoyasu Fukushima4, Naofumi Suyama5, Shigeru Kohno3, Kazuhiro Tsukamoto1
1Department of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan
2Department of Pharmacy, Nagasaki University Hospital, Nagasaki 852-8501, Japan
3Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501, Japan
4Division of Internal Medicine, Japanese Red Cross Nagasaki Genbaku Isahaya Hospital, Isahaya 859-0497, Japan
5Department of Internal Medicine, Nagasaki Municipal Medical Center, Nagasaki 852-8012, Japan

Tài liệu tham khảo

World Health Organization: global tuberculosis control 2009-epidemiology, strategy, financing: WHO report 2009, WHO/HTM/TB/2009.411. World Health Organization, Geneva, Switzerland. Dye, 2002, Worldwide incidence of multidrug-resistant tuberculosis, J Infect Dis, 185, 1197, 10.1086/339818 Corbett, 2003, The growing burden of tuberculosis: global trends and interactions with the HIV epidemic, Arch Intern Med, 163, 1009, 10.1001/archinte.163.9.1009 Pande, 1996, Risk factors for hepatotoxicity from antituberculosis drugs: a case-control study, Thorax, 51, 132, 10.1136/thx.51.2.132 Dossing, 1996, Liver injury during antituberculosis treatment: an 11-year study, Tuber Lung Dis, 77, 335, 10.1016/S0962-8479(96)90098-2 Devoto, 1997, Risk factors for hepatotoxicity induced by antituberculosis drugs, Acta Physiol Pharmacol Ther Latinoam, 47, 197 Wong, 2000, Antituberculosis drug-related liver dysfunction in chronic hepatitis B infection, Hematology, 31, 201 Shakya, 2004, Incidence of hepatotoxicity due to antitubercular medicines and assessment of risk factors, Ann Pharmacophore, 38, 1074, 10.1345/aph.1D525 Ungo, 1998, Antituberculosis drug-induced hepatotoxicity. The role of hepatitis C virus and the human immunodeficiency virus, Am J Respir Crit Care Med, 157, 1871, 10.1164/ajrccm.157.6.9711039 Ohno, 2000, Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity, Int J Tuberc Lung Dis, 4, 256 Huang, 2002, Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis, Hepatology, 35, 883, 10.1053/jhep.2002.32102 Hussain, 2003, Antituberculosis drug-induced hepatitis: risk factors, prevention and management, Indian J Exp Biol, 41, 1226 Shimizu, 2006, DNA microarray genotyping of N-acetyltransferase 2 polymorphism using carbodiimide as the linker for assessment of isoniazid hepatotoxicity, Tuberculosis, 86, 374, 10.1016/j.tube.2005.09.002 Higuchi, 2007, NAT2∗6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis, World J Gastroenterol, 13, 6003, 10.3748/wjg.v13.45.6003 Huang, 2003, Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis, Hepatology, 37, 924, 10.1053/jhep.2003.50144 Roy, 2001, Increased risk of antituberculosis drug-induced hepatotoxicity in individuals with glutathione S-transferase M1 ’null’ mutation, J Gastroenterol Hepatol, 16, 1033, 10.1046/j.1440-1746.2001.02585.x Sharma, 2002, Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment, Am J Respir Crit Care Med, 166, 916, 10.1164/rccm.2108091 Timbrell, 1979, Studies on the role of acetylhydrazine in isoniazid hepatotoxicity, Arch Toxicol Suppl, 2, 1, 10.1007/978-3-642-67265-1_1 Noda, 1983, Is isoniazid-hepatotoxicity induced by the metabolite, hydrazine?, J UOEH, 5, 183 Lauterburg, 1985, Oxidation of hydrazine metabolites formed from isoniazid, Clin Pharmacol Ther, 38, 566, 10.1038/clpt.1985.225 Sodhi, 1996, Study of oxidative stress in isoniazid-induced hepatic injury in young rats with and without protein-energy malnutrition, J Biochem Toxicol, 11, 139, 10.1002/(SICI)1522-7146(1996)11:3<139::AID-JBT6>3.0.CO;2-L Zhen, 2008, Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species, Am J Hypertens, 21, 28, 10.1038/ajh.2007.14 Jaeschke, 2003, The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity, Toxicol Lett, 144, 279, 10.1016/S0378-4274(03)00239-X Talalay, 2003, Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis, Adv Enzym Regul, 43, 121, 10.1016/S0065-2571(02)00038-9 Primiano, 1997, Antioxidant-inducible genes, Adv Pharmacol, 38, 293, 10.1016/S1054-3589(08)60989-8 Itoh, 1997, An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements, Biochem Biophys Res Commun, 236, 313, 10.1006/bbrc.1997.6943 Oyake, 2006, Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site, Mol Cell Biol, 16, 6083, 10.1128/MCB.16.11.6083 Igarashi, 1998, Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for γ-globin locus control region complex, J Biol Chem, 273, 11783, 10.1074/jbc.273.19.11783 Itoh, 1999, Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain, Genes Dev, 13, 76, 10.1101/gad.13.1.76 Suzuki, 2004, Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1, EMBO J, 23, 2544, 10.1038/sj.emboj.7600248 2000, American Thoracic Society: diagnostic standards and classification of tuberculosis in adults and children, Am J Respir Crit Care Med, 161, 1376 Benichou, 1990, Criteria of drug-induced liver disorders. Report of an international consensus meeting, J Hepatol, 11, 272, 10.1016/0168-8278(90)90124-A 2007, The International HapMap Consortium: a second generation human haplotype map of over 3.1 million SNPs, Nature, 449, 851, 10.1038/nature06258 Barrett, 2005, Haploview: analysis and visualization of LD and haplotype maps, Bioinformatics, 21, 263, 10.1093/bioinformatics/bth457 Ogawa, 2001, Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1, EMBO J, 20, 2835, 10.1093/emboj/20.11.2835 MacLeod, 2009, Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds, Carcinogenesis, 30, 1571, 10.1093/carcin/bgp176 Knight, 2001, Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress, Toxicol Sci, 62, 212, 10.1093/toxsci/62.2.212 Kon, 2004, Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes, Hepatology, 40, 1170, 10.1002/hep.20437 Cover, 2005, Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity, J Pharmacol Exp Ther, 315, 879, 10.1124/jpet.105.088898 Yoh, 2001, Transgenic over-expression of MafK suppresses T cell proliferation and function in vivo, Genes Cells, 6, 1055, 10.1046/j.1365-2443.2001.00489.x Gardner, 1998, Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat, Hepatology, 27, 748, 10.1002/hep.510270316 Gardner, 2002, Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10, Toxicol Appl Pharmacol, 184, 27, 10.1006/taap.2002.9474 Pryor, 1995, The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide, Am J Physiol, 268, L699 Moreno, 1992, Inactivation of α1-proteinase inhibitor by peroxynitrite, Chem Res Toxicol, 5, 425, 10.1021/tx00027a017