Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions

Leeder, 1998, Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs, Epilepsia, 39, S8, 10.1111/j.1528-1157.1998.tb01679.x

Vittorio, 1995, Anticonvulsant hypersensitivity syndrome, Arch Intern Med, 155, 2285, 10.1001/archinte.1995.00430210033005

Tennis, 1997, Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study, Neurology, 49, 542, 10.1212/WNL.49.2.542

Roujeau, 1994, Severe adverse cutaneous reactions to drugs, N Engl J Med, 331, 1272, 10.1056/NEJM199411103311906

Roujeau, 2005, Clinical heterogeneity of drug hypersensitivity, Toxicology, 209, 123, 10.1016/j.tox.2004.12.022

Roujeau, 1994, The spectrum of Stevens–Johnson syndrome and toxic epidermal necrolysis: a clinical classification, J Invest Dermatol, 102, 28S, 10.1111/1523-1747.ep12388434

Kerr, 1994, Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation, Biochem Pharmacol, 47, 1969, 10.1016/0006-2952(94)90071-X

Madden, 1996, Bioactivation of carbamazepine in the rat in vivo. Evidence for the formation of reactive arene oxide(s), Drug Metab Dispos, 24, 469

Bellucci, 1987, The metabolism of carbamazepine in humans: steric course of the enzymatic hydrolysis of the 10,11-epoxide, J Med Chem, 30, 768, 10.1021/jm00388a004

Lillibridge, 1996, Protein-reactive metabolites of carbamazepine in mouse liver microsomes, Drug Metab Dispos, 24, 509

Gaedigk, 1994, Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions, Pharmacogenetics, 4, 142, 10.1097/00008571-199406000-00005

Green, 1995, Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity, Biochem Pharmacol, 50, 1353, 10.1016/0006-2952(95)02009-8

Mauri-Hellweg, 1995, Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine, J Immunol, 155, 462, 10.4049/jimmunol.155.1.462

Nassif, 2002, Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis, J Invest Dermatol, 118, 728, 10.1046/j.1523-1747.2002.01622.x

Naisbitt, 2003, Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones, Mol Pharmacol, 63, 732, 10.1124/mol.63.3.732

Nassif, 2004, Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells, J Allergy Clin Immunol, 114, 1209, 10.1016/j.jaci.2004.07.047

Schnyder, 1997, Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones, J Clin Invest, 100, 136, 10.1172/JCI119505

Chung, 2004, Medical genetics: a marker for Stevens–Johnson syndrome, Nature, 428, 486, 10.1038/428486a

Sullivan, 2001, The drug hypersensitivity syndrome: what is the pathogenesis?, Arch Dermatol, 137, 357

Smigielski, 2000, dbSNP: a database of single nucleotide polymorphisms, Nucleic Acids Res, 28, 352, 10.1093/nar/28.1.352

Walsh, 2003, An integrated haplotype map of the human major histocompatibility complex, Am J Hum Genet, 73, 580, 10.1086/378101

Pirmohamed, 2001, TNFalpha promoter region gene polymorphisms in carbamazepine-hypersensitive patients, Neurology, 56, 890, 10.1212/WNL.56.7.890

Martin, 2004, Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant, Proc Natl Acad Sci USA, 101, 4180, 10.1073/pnas.0307067101

Middleton, 2002, Current and emerging technology for HLA typing, Int J Hematol, 76, 150, 10.1007/BF03165106

Tilanus, 2002, Technical manual of the Thirteenth International Histocompatibility Working Group (IHWG), genomic analysis of the human MHC DNA-based typing for HLA alleles and linked polymorphisms

Hung, 2005, HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol, Proc Natl Acad Sci USA, 102, 4134, 10.1073/pnas.0409500102

Chu, 2001, Diversity of HLA among Taiwan's indigenous tribes and the Ivatans in the Philippines, Tissue Antigens, 58, 9, 10.1034/j.1399-0039.2001.580102.x

Schaid, 1999, Biased tests of association: comparisons of allele frequencies when departing from Hardy–Weinberg proportions, Am J Epidemiol, 149, 706, 10.1093/oxfordjournals.aje.a009878

Haldane, 1956, The estimation and significance of the logarithm of a ratio of frequencies, Ann Hum Genet, 20, 309, 10.1111/j.1469-1809.1955.tb01285.x

Hung, 2005, HLA-B genotyping to detect carbamazepine-induced Stevens–Johnson syndrome: implications for personalizing medicine, Personal Med, 2, 225, 10.2217/17410541.2.3.225

Roujeau, 1995, Medication use and the risk of Stevens–Johnson syndrome or toxic epidermal necrolysis, N Engl J Med, 333, 1600, 10.1056/NEJM199512143332404

Horton, 2004, Gene map of the extended human MHC, Nat Rev Genet, 5, 889, 10.1038/nrg1489

Pichler, 2002, Modes of presentation of chemical neoantigens to the immune system, Toxicology, 181–182, 49, 10.1016/S0300-483X(02)00254-8

Mallal, 2002, Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir, Lancet, 359, 727, 10.1016/S0140-6736(02)07873-X