Genetic analysis of the wing vein pattern of Drosophila
Tóm tắt
Of the many mutations known to affect the wing vein pattern we have selected the most extreme in 29 genes for study. Their phenotype can be classified in two major classes: lack-of-veins and excess-of-veins, and in several internally coherent groups. The study of multiple mutant combinations, within groups and between groups, reveals several genetic operations at work in the generation of the vein pattern. The finding that some of these mutations also affect cell proliferation in characteristic ways has prompted a generative model of wing morphogenetic and pattern formation based on cell behaviour properties defined by the corresponding wild-type genes.
Tài liệu tham khảo
Akam M (1987) The molecular basis for metameric pattern in Drosophila embryo. Development 101:1–22
Anderson DT (1972) The development of hemimetabolous insects. In: Counce SJ, Waddington CH (eds) Developmental systems: insects, vol 1. Academic Press, London New York, pp 95–163
Bryant P (1970) Cell lineage relationships in the imaginai wing disc of Drosophila melanogaster. Dev Biol 22:398–411
Busson D, Limbourg-Bouchon B, Mariol MC, Preat T, Laumour-Isnard C (1988) Genetic analysis of viable and lethal fused mutants of Drosophila melanogaster. Roux's Arch Dev Biol 197:221–230
Canal I (1988) Análisis genético del metamerismo en el sistema nervioso embrionario de Drosophila melanogaster. Ph.D. Dissertation. Universidad Autónoma de Madrid, Spain
de la Concha A, Dietrich U, Weigel D, Campos-Ortega JA (1988) Functional interactions of neurogenic genes of Drosophila melanogaster. Genetics 118:499–508
Craymer L (1980) Ach: Achaetous. Drosophila Information Service 55:197
Fausto-Sterling A (1978) Pattern formation in the wing veins of the fused mutant (Drosophila melanogaster). Dev Biol 63:358–369
Ferris GF (1965) External morphology of the adult. In: Demerec MW (ed) Biology of Drosophila. Hafner, London New York, pp 368–418
García Alonso L, García-Bellido A (1986) Genetic analysis of Hairy-wing mutations. Roux's Arch Dev Biol 195:259–264
García Alonso L, García-Bellido A (1988) Extramacrochaete, a trans-acting gene of the achaete-scute complex of Drosophila involved in cell communication. Roux's Arch Dev Biol 197:328–338
García-Bellido A (1977) Inductive mechanisms in the process of the wing vein formation in Drosophila. Roux's Arch Dev Biol 182:93–106
García-Bellido A (1981) From the gene to the pattern: chaeta differentiation. In: Lloyd CW, Rees DA (eds) Cellular controls in differentiation. Academic Press, New York, pp 281–304
García-Bellido A, Merriam JR (1971a) Parameters of the wing imaginai disc development of Drosophila melanogaster. Dev Biol 24:61–87
García-Bellido A, Merriam JR (1971b) Genetic analysis of cell heredity in imaginal discs of Drosophila melanogaster. Proc Natl Acad Sci USA 68:2222–2226
Garcá-Bellido A, Santamaría P (1972) Developmental analysis of the wing disc in the mutant engrailed of Drosophila melanogaster. Genetics 72:87–104
Garcá-Bellido A, Santamaría P (1978) Developmental analysis of the achaete-scute system of Drosophila melanogaster. Genetics 88:469–486
Ghysen A, Dambly-Chaudiere C (1988) From DNA to form: the achaete-scute complex. Genes Dev 2:495–501
Hadorn E (1948) Gene action in growth and differentiation of lethal mutant of Drosophila. Symp Soc Exp Biol 2:177–195
Ingham PW (1988) The molecular genetics of embryonic pattern formation in Drosophila. Nature 335:25–34
Irish VF, Gelbart WM (1987) The decapentaplegic gene is required for dorsal-ventral pattering of the Drosophila embryo. Genes Dev 1:868–879
Jürgen G, Wieschaus E, Nüsslein-Volhard C, Kluding H (1984) Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. II. Zygotic loci on the third chromosome. Roux's Arch Dev Biol 193:283–295
Lewis EB (1951) Psedoallelism and gene evolution. Cold Spring Harbor Symp Quant Biol 16:159–174
Lewis EB, Bacher F (1968) Method of feeding ethyl methanesulphonate (EMS) to Drosophila males. Drosophila Information Service 43:193
Lindsley DL, Grell EH (1968) Genetic variations of Drosophila melanogaster. Carnegie Inst Wash Publ 627
Martinez-Arias A (1985) The development of fused-embryos of Drosophila melanogaster. J Embryol Exp Morphol 87:99–114
Mayer U, Nüsslein-Volhard C (1988) A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo. Genes Dev 2:1496–1511
Nüsslein-Volhard C, Wieschaus E (1980) Segmentation in Drosophila: mutations affecting segment number and polarity. Nature 287:795–801
Nüsslein-Volhard C, Wieschaus E, Kluding H (1984) Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome. Roux's Arch Dev Biol 193:267–282
Orenic T, Chidsey J, Holmgren R (1987) Cell and cubitus interruptus Dominant: two segment polarity genes on the fourth chromosome in Drosophila. Dev Biol 124:50–56
Portin P (1975) Allelic negative complementation at the Abruptex locus of Drosophila melanogaster. Genetics 116:433–445
Preiss A, Hartley DA, Artavanis-Tsakonas S (1988) The molecular genetic of Enhancer of split, a gene required for embryonic neural development in Drosophila. EMBO J 7:3917–3927
Puro J (1982a) Drosophila Information Service 58:205
Puro J (1982b) Drosophila Information Service 58:206
Ruiz-Gomez M, Modolell J (1987) Deletion analysis of the achaetescute locus of Drosophila melanogaster. Genes Dev 1:1238–1246
Schubiger M, Palka I (1987) Changing spatial patterns of DNA replication in the developing wing of Drosophila. Dev Biol 123:145–153
Segal D, Gelbart WM (1985) shortvein, a new component of the decapentaplegic gene complex in Drosophila melanogaster. Genetics 109:119–143
Snodgrass RE (1936) The principles of insect morphology. McGrawn-Hill, New York
Spencer FA, Hoffmann FM, Gelbart WM (1982) Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster. Cell 28:451–461
Stern C (1954) Two or three bristles. Am Sci 42:213–247
Szidonya J, Reuter G (1988) Cytogenetic analysis of the echinoid (ed), dumpy (dp) and clot (cl) region in Drosophila melanogaster. Genet Res 51:197–208
Vässin H, Campos-Ortega JA (1987) Genetic analysis of Delta, a neurogenic gene of Drosophila melanogaster. Genetics 116:433–445
Vässin H, Vielmetter J, Campos-Ortega JA (1985) Genetic interactions in early neurogenesis of Drosophila melanogaster. J Neurogenet 2:291–308
Waddington CH (1940) The genetic control of wing development in Drosophila. J Genet 41:75–139
Wharton KA, Johansen KM, Xu T, Artavanis-Tsakonas S (1985) Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43:567–581
Wieschaus E, Nüsslein-Volhard C (1986) Looking at embryos. In: Roberts DB (ed) Drosophila, a practical approach. IRL Press, Oxford Washington, pp 199–228