Genetic Markers for Prediction of Normal Tissue Toxicity After Radiotherapy
Tóm tắt
Từ khóa
Tài liệu tham khảo
Andreassen, 2002, Does variability in normal tissue reactions after radiotherapy have a genetic basis—Where and how to look for it?, Radiother Oncol, 64, 131, 10.1016/S0167-8140(02)00154-8
Fernet, 2004, Genetic biomarkers of therapeutic radiation sensitivity, DNA Repair (Amst), 3, 1237, 10.1016/j.dnarep.2004.03.019
Andreassen, 2005, Can risk of radiotherapy-induced normal tissue complications be predicted from genetic profiles?, Acta Oncol, 44, 801, 10.1080/02841860500374513
West, 2007, The genomics revolution and radiotherapy, Clin Oncol (R Coll Radiol), 19, 470, 10.1016/j.clon.2007.02.016
Lander, 2001, Initial sequencing and analysis of the human genome, Nature, 409, 860, 10.1038/35057062
Liu, 2006, A geographically explicit genetic model of worldwide human-settlement history, Am J Hum Genet, 79, 230, 10.1086/505436
Manica, 2007, The effect of ancient population bottlenecks on human phenotypic variation, Nature, 448, 346, 10.1038/nature05951
Hirschhorn, 2005, Genome-wide association studies for common diseases and complex traits, Nat Rev Genet, 6, 95, 10.1038/nrg1521
Li, 2006, Haplotype-based quantitative trait mapping using a clustering algorithm, BMC Bioinformatics, 7, 258, 10.1186/1471-2105-7-258
Satagopan, 2002, Two-stage designs for gene-disease association studies, Biometrics, 58, 163, 10.1111/j.0006-341X.2002.00163.x
Easton, 2007, Genome-wide association study identifies novel breast cancer susceptibility loci, Nature, 447, 1087, 10.1038/nature05887
Cox, 2007, A common coding variant in CASP8 is associated with breast cancer risk, Nat Genet, 39, 352, 10.1038/ng1981
2007, Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls, Nature, 447, 661, 10.1038/nature05911
Parkes, 2007, Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn’s disease susceptibility, Nat Genet, 39, 830, 10.1038/ng2061
Todd, 2007, Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes, Nat Genet, 39, 857, 10.1038/ng2068
Zeggini, 2007, Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes, Science, 316, 1336, 10.1126/science.1142364
Frayling, 2007, A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity, Science, 316, 889, 10.1126/science.1141634
Saxena, 2007, Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels, Science, 316, 1331, 10.1126/science.1142358
Marchini, 2007, A new multipoint method for genome-wide association studies by imputation of genotypes, Nat Genet, 39, 906, 10.1038/ng2088
2007, Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project, Nature, 447, 799, 10.1038/nature05874
Rogers, 2000, Four radiation hypersensitivity cases and their implications for clinical radiotherapy, Radiother Oncol, 57, 143, 10.1016/S0167-8140(00)00249-8
Bentzen, 1991, Relationship between early and late normal-tissue injury after postmastectomy radiotherapy, Radiother Oncol, 20, 159, 10.1016/0167-8140(91)90092-U
Bentzen, 1993, Clinical correlations between late normal tissue endpoints after radiotherapy: implications for predictive assays of radiosensitivity, Eur J Cancer, 29A, 1373, 10.1016/0959-8049(93)90004-Y
Andreassen, 2005, TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer, Radiother Oncol, 75, 18, 10.1016/j.radonc.2004.12.012
Andreassen, 2003, Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes, Radiother Oncol, 69, 127, 10.1016/j.radonc.2003.09.010
Hölscher, 2006, Influence of connective tissue diseases on the expression of radiation side effects: A systematic review, Radiother Oncol, 78, 123, 10.1016/j.radonc.2005.12.013
Overgaard, 1987, The value of the NSD formula in equation of acute and late radiation complications in normal tissue following 2 and 5 fractions per week in breast cancer patients treated with postmastectomy irradiation, Radiother Oncol, 9, 1, 10.1016/S0167-8140(87)80213-X
Bentzen, 1989, Early and late normal-tissue injury after postmastectomy radiotherapy alone or combined with chemotherapy, Int J Radiat Biol, 56, 711, 10.1080/09553008914551941
Andreassen, 2006, Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1. SOD2, XRCC1, XRCC3, APEX and ATM– a study based on DNA from formalin fixed paraffin embedded tissue samples, Int J Radiat Biol, 82, 577, 10.1080/09553000600876637
Cesaretti, 2007, A genetically determined dose-volume histogram predicts for rectal bleeding among patients treated with prostate brachytherapy, Int J Radiat Oncol Biol Phys, 68, 10.1016/j.ijrobp.2007.02.052
Brem, 2006, The XRCC1-77T->C variant: haplotypes, breast cancer risk, response to radiotherapy and the cellular response to DNA damage, Carcinogenesis, 27, 2469, 10.1093/carcin/bgl114
Syrris, 1998, Transforming growth factor-beta1 gene polymorphisms and coronary artery disease, Clin Sci (Lond), 95, 659, 10.1042/CS19980154
Awad, 1998, Genotypic variation in the transforming growth factor-beta1 gene: Association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation, Transplantation, 66, 1014, 10.1097/00007890-199810270-00009
Grainger, 1999, Genetic control of the circulating concentration of transforming growth factor type beta1, Hum Mol Genet, 8, 93, 10.1093/hmg/8.1.93
Hinke, 2001, Association of transforming growth factor-beta1 (TGFbeta1) T29 –> C gene polymorphism with bone mineral density (BMD), changes in BMD, and serum concentrations of TGF-beta1 in a population-based sample of postmenopausal german women, Calcif Tissue Int, 69, 315, 10.1007/s002230020024
Hoffmann, 2002, Ethnicity greatly influences cytokine gene polymorphism distribution, Am J Transplant, 2, 560, 10.1034/j.1600-6143.2002.20611.x
Bentzen, 1989, Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study, Radiother Oncol, 15, 267, 10.1016/0167-8140(89)90095-9
Jung, 2001, Quantification of late complications after radiation therapy, Radiother Oncol, 61, 233, 10.1016/S0167-8140(01)00457-1
Ho, 2006, Genetic predictors of adverse radiotherapy effects: The Gene-PARE project, Int J Radiat Oncol Biol Phys, 65, 646, 10.1016/j.ijrobp.2006.03.006
Iwakawa, 2002, RadGenomics project, Nippon Igaku Hoshasen Gakkai Zasshi, 62, 484
Burnet, 2006, Radiosensitivity, radiogenomics and RAPPER, Clin Oncol (R Coll Radiol), 18, 525, 10.1016/j.clon.2006.05.007
Pan, 2006, Using endophenotypes for pathway clusters to map complex disease genes, Genet Epidemiol, 30, 143, 10.1002/gepi.20136
Johansen, 1996, Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy, Radiother Oncol, 40, 101, 10.1016/0167-8140(96)01777-X
West, 2001, Lymphocyte radiosensitivity is a significant prognostic factor for morbidity in carcinoma of the cervix, Int J Radiat Oncol Biol Phys, 51, 10, 10.1016/S0360-3016(01)01575-9
Borgmann, 2002, Indicators of late normal tissue response after radiotherapy for head and neck cancer: Fibroblasts, lymphocytes, genetics, Radiother Oncol, 64, 141, 10.1016/S0167-8140(02)00167-6
Hoeller, 2003, Individual radiosensitivity measured with lymphocytes may be used to predict the risk of fibrosis after radiotherapy for breast cancer, Radiother Oncol, 69, 137, 10.1016/j.radonc.2003.10.001
Rieger, 2004, Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage, Proc Natl Acad Sci U S A, 101, 6635, 10.1073/pnas.0307761101
Svensson, 2006, Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity, PLoS Med, 3, e422, 10.1371/journal.pmed.0030422
Rødningen OK, Børresen-Dale AL, Alsner J, et al: Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis. Radiother Oncol (in press)
Alsner, 2007, Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis, Radiother Oncol, 83, 261, 10.1016/j.radonc.2007.05.001
Herskind, 1998, Differentiation state of skin fibroblast cultures versus risk of subcutaneous fibrosis after radiotherapy, Radiother Oncol, 47, 263, 10.1016/S0167-8140(98)00018-8
Herskind, 2000, Fibroblast differentiation in subcutaneous fibrosis after postmastectomy radiotherapy, Acta Oncol, 39, 383, 10.1080/028418600750013159
Travis, 2007, Genetic susceptibility to late normal tissue injury, Semin Radiat Oncol, 17, 149, 10.1016/j.semradonc.2006.11.011
Kruse, 2007, Gene expression arrays as a tool to unravel mechanisms of normal tissue radiation injury and prediction of response, World J Gastroenterol, 13, 2669, 10.3748/wjg.v13.i19.2669
Ahn, 2006, Polymorphisms in genes related to oxidative stress (CAT. MnSOD, MPO, and eNOS) and acute toxicities from radiation therapy following lumpectomy for breast cancer, Clin Cancer Res, 12, 7063, 10.1158/1078-0432.CCR-06-0039
Ambrosone, 2006, Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: A case-series study, Breast Cancer Res, 8, R40, 10.1186/bcr1526
Andreassen, 2006, ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy, Int J Radiat Oncol Biol Phys, 64, 776, 10.1016/j.ijrobp.2005.09.014
Angele, 2003, ATM haplotypes and cellular response to DNA damage: association with breast cancer risk and clinical radiosensitivity, Cancer Res, 63, 8717
Appleby, 1997, Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy, Br J Cancer, 76, 1546, 10.1038/bjc.1997.593
Bremer, 2003, Clinical radiosensitivity in breast cancer patients carrying pathogenic ATM gene mutations: No observation of increased radiation-induced acute or late effects, Radiother Oncol, 69, 155, 10.1016/j.radonc.2003.08.004
Cesaretti, 2005, ATM sequence variants are predictive of adverse radiotherapy response among patients treated for prostate cancer, Int J Radiat Oncol Biol Phys, 61, 196, 10.1016/j.ijrobp.2004.09.031
Chang-Claude, 2005, Association between polymorphisms in the DNA repair genes, Clin Cancer Res, 11, 4802, 10.1158/1078-0432.CCR-04-2657
Clarke, 1998, Absence of ATM truncations in patients with severe acute radiation reactions, Int J Radiat Oncol Biol Phys, 41, 1021, 10.1016/S0360-3016(98)00171-0
Damaraju, 2006, Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer, Clin Cancer Res, 12, 2545, 10.1158/1078-0432.CCR-05-2703
De Ruyck, 2005, Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: Association with single nucleotide polymorphisms in XRCC1. XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes, Int J Radiat Oncol Biol Phys, 62, 1140, 10.1016/j.ijrobp.2004.12.027
De Ruyck, 2005, Microsatellite polymorphisms in DNA repair genes XRCC1. XRCC3 and XRCC5 in patients with gynecological tumors: Association with late clinical radiosensitivity and cancer incidence, Radiat Res, 164, 237, 10.1667/RR3417.1
De Ruyck, 2006, TGFbeta1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors, Int J Radiat Oncol Biol Phys, 65, 1240, 10.1016/j.ijrobp.2006.03.047
Edvardsen, 2007, Germline glutathione S-transferase variants in breast cancer: Relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy, Int J Radiat Oncol Biol Phys, 67, 1163, 10.1016/j.ijrobp.2006.11.009
Gaffney, 1998, Response to radiation therapy and prognosis in breast cancer patients with BRCA1 and BRCA2 mutations, Radiother Oncol, 47, 129, 10.1016/S0167-8140(98)00023-1
Giotopoulos, 2007, The late radiotherapy normal tissue injury phenotypes of telangiectasia, fibrosis and atrophy in breast cancer patients have distinct genotype-dependent causes, Br J Cancer, 96, 1001, 10.1038/sj.bjc.6603637
Green, 2002, Variation in the manganese superoxide dismutase gene (SOD2) is not a major cause of radiotherapy complications in breast cancer patients, Radiother Oncol, 63, 213, 10.1016/S0167-8140(02)00079-8
Hall, 1998, A preliminary report: Frequency of A-T heterozygotes among prostate cancer patients with severe late responses to radiation therapy, Cancer J Sci Am, 4, 385
Ho, 2007, Possession of ATM sequence variants as predictor for late normal tissue responses in breast cancer patients treated with radiotherapy, Int J Radiat Oncol Biol Phys, 69, 677, 10.1016/j.ijrobp.2007.04.012
Iannuzzi, 2002, ATM mutations in female breast cancer patients predict for an increase in radiation-induced late effects, Int J Radiat Oncol Biol Phys, 52, 606, 10.1016/S0360-3016(01)02684-0
Kornguth, 2005, Gastrostomy in oropharyngeal cancer patients with ERCC4 (XPF) germline variants, Int J Radiat Oncol Biol Phys, 62, 665, 10.1016/j.ijrobp.2004.11.026
Leong, 2000, Mutation analysis of BRCA1 and BRCA2 cancer predisposition genes in radiation hypersensitive cancer patients, Int J Radiat Oncol Biol Phys, 48, 959, 10.1016/S0360-3016(00)00728-8
Moullan, 2003, Polymorphisms in the DNA repair gene XRCC1, breast cancer risk, and response to radiotherapy, Cancer Epidemiol Biomarkers Prev, 12, 1168
Oppitz, 1999, Sequence analysis of the ATM gene in 20 patients with RTOG grade 3 or 4 acute and/or late tissue radiation side effects, Int J Radiat Oncol Biol Phys, 44, 981, 10.1016/S0360-3016(99)00108-X
Pierce, 2000, Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations, J Clin Oncol, 18, 3360, 10.1200/JCO.2000.18.19.3360
Popanda, 2006, Genetic polymorphisms in the DNA double-strand break repair genes XRCC3. XRCC2, and NBS1 are not associated with acute side effects of radiotherapy in breast cancer patients, Cancer Epidemiol Biomarkers Prev, 15, 1048, 10.1158/1055-9965.EPI-06-0046
Price, 1997, Rare microsatellite polymorphisms in the DNA repair genes XRCC1. XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivity, Somat Cell Mol Genet, 23, 237, 10.1007/BF02674415
Quarmby, 2003, Association of transforming growth factor beta-1 single nucleotide polymorphisms with radiation-induced damage to normal tissues in breast cancer patients, Int J Radiat Biol, 79, 137, 10.1080/713865032
Ramsay, 1998, Testing for mutations of the ataxia telangiectasia gene in radiosensitive breast cancer patients, Radiother Oncol, 47, 125, 10.1016/S0167-8140(98)00014-0
Severin, 2001, Novel DNA sequence variants in the hHR21 DNA repair gene in radiosensitive cancer patients, Int J Radiat Oncol Biol Phys, 50, 1323, 10.1016/S0360-3016(01)01608-X
Shayeghi, 1998, Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients, Br J Cancer, 78, 922, 10.1038/bjc.1998.602
Tan, 2006, Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients, Breast Cancer Res Treat, 97, 255, 10.1007/s10549-005-9119-2