Genes Involved in Viral Carcinogenesis and Tumor Initiation in Hepatitis C Virus-Induced Hepatocellular Carcinoma

Molecular Medicine - Tập 15 Số 3-4 - Trang 85-94 - 2009
Valeria R. Mas1, Daniel G. Maluf2, Kellie J. Archer3, Kenneth Yanek2, Xiangrong Kong3, Laura Kulik4, Chris E. Freise5, Kim M. Olthoff6, Rafik M. Ghobrial7, Paula McIver8, Robert A. Fisher2
1Division of Transplantation, Department of Surgery, West Hospital ninth floor, Virginia Commonwealth University, Richmond, USA
2Division of Transplantation, Department of Surgery, West Hospital ninth floor, Virginia Commonwealth University, 1200 East Broad Street, PO Box 980057, Richmond, Virginia, 23298-0057, USA
3Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia, USA
4Department of Medicine, Northwestern University, Chicago, Illinois, USA
5Department of Surgery, University of California, San Francisco, California, USA
6Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
7Department of Surgery, University of California, Los Angeles, California, USA
8Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Parkin DM, Bray F, Ferlay J, Pisani P. (2001) Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 94:153–6.

Tagger A, et al. (1999) Case-control study on hepatitis C virus (HCV) as a risk factor for hepato-cellular carcinoma: the role of HCV genotypes and the synergism with hepatitis B virus and alcohol. Brescia HCC Study. Int. J. Cancer 81:695–9.

Tsukuma H, et al. (1993) Risk factors for hepato-cellular carcinoma patients with chronic liver disease. N. Engl. J. Med.. 328:1797–801.

El-Serag HB, Mason AC. (1999) Rising incidence of hepatocellular carcinoma in the United States. N. Engl. J. Med. 340:745–50.

Marsh JW, Dvorchik I. (2003) Liver organ allocation for hepatocellular carcinoma: are we sure? Liver Transpl. 9:693–6.

Fisher RA, et al. (2007) Is hepatic transplantation justified for primary liver cancer? J Surg. Oncol. 95:674–9.

Barnett CC Jr, Curley SA. (2001) Ablative techniques for hepatocellular carcinoma. Semin. Oncol. 28:487–96.

Figueras J, et al. (2000) Resection or transplantation for hepatocellular carcinoma in cirrhotic patients: outcomes based on indicated treatment strategy. J. Am. Coll. Surg. 190:580–7.

Iwatsuki S, et al. (2000) Liver transplantation for hepatocellular carcinoma: a proposal of a prognostic scoring system. J. Am. Coll. Surg. 191:389–94.

Marsh JW, et al. (2003) Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival. Liver Transpl. 7:664–71.

Nam SW, et al. (2005) Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 42:809–18.

Iizuka N, et al. (2003) Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet 361:923–9.

Mas VR, et al. (2007) Genes associated with progression and recurrence of hepatocellular carcinoma in hepatitis C patients waiting and undergoing liver transplantation: preliminary results. Transplantation 83:973–81.

Mas VR, et al. (2006) Differentially expressed genes between early and advanced hepatocellular carcinoma (HCC) as a potential tool for selecting liver transplant recipients. Mol. Med. 12:97–104.

Moinzadeh P, Breuhahn K, Stutzer H, Schirmacher P. (2005) Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade — results of an explorative CGH meta-analysis. Br. J. Cancer 92:935–41.

Schafer DF, Sorrell MF. (1999) Hepatocellular carcinoma. Lancet 353:1253–7.

El-Serag HB. (2002) Hepatocellular carcinoma and hepatitis C in the United States. Hepatology 36: S74–83.

Guan XY, et al. (2000) Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer 29:110–6.

Marchio A, et al. (2001) Chromosomal abnormalities in liver cell dysplasia detected by comparative genomic hybridization. Mol. Pathol. 54:270–4.

Wong N, et al. (2001) Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma. Am. J. Pathol. 159:465–71.

Nishida N, et al. (2003) Chromosomal instability and human hepatocarcinogenesis. Histol. Histopathol. 18:897–909.

Buendia MA. (2002) Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects. Med. Pediatr. Oncol. 39:530–5.

Taniguchi K, et al. (2002) Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 21:4863–71.

Al-Sukhun S, Hussain M. (2003) Current understanding of the biology of advanced bladder cancer. Cancer 97:2064–75.

Theodorescu D (2003). Molecular pathogenesis of urothelial bladder cancer. Histol. Histopathol. 18:259–74.

Iizuka N, et al. (2002) Comparison of gene expression profiles between hepatitis B virus-and hepatitis C virus-infected hepatocellular carcinoma by oligonucleotide microarray data on the basis of a supervised learning method. Cancer Res. 62:3939–44.

Okabe H, et al. (2001) Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res. 61:2129–37.

Shirota Y, Kaneko S, Honda M, Kawai HF, Kobayashi K. (2001) Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays. Hepatology 33:832–840.

American Liver Tumor Study Group. (1998) A randomized prospective multi-institutional trial of orthotopic liver transplantation or partial hepatic resection with or without adjuvant chemotherapy for hepatocellular carcinoma. Investigators Booklet and protocol 1998. United Network for Organ Sharing. Policy 3.6.4.4.1998.

Knodell RG, et al. (1981) Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1:431–5.

Gentleman RC, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5:R80.

R Development Core Team. R: a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2007.

Gautier L, Cope L, Bolstad BM, Irizarry RA. (2004) affy-analysi of Affymetrix GeneChip data at the probe level. Bioinformatics 20:307–15.

Huber W, Gentleman R. (2004) matchprobes: a Bioconductor package for the sequence-matching of microarray probe elements. Bioinformatics 20:1651–2.

Irizarry RA, et al. (2003) Exploration, normalization, and summaries of high density oligonucletide array probe level data. Biostatistics 4:249–64.

Irizarry RA, et al. (2003) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 31:e15.

Smyth GK. (2005) Limma: linear models for microarray data. In: Gentleman R, Carey VJ, Dudoit S, Irizarry R, Huber W, editors. Bioinformatics and computational biology solutions using R and Bioconductor. New York: Springer; p. 397–420.

Llovet JM, Burroughs A, Bruix J. (2003) Hepato-cellular carcinoma. Lancet 362:1907–17.

Gao Q, et al. (2008) Selection of reference genes for real-time PCR in human hepatocellular carcinoma tissues. J. Cancer Res. Clin. Oncol. 134:979–86.

Waxman S, Wurmbach E. (2007) De-regulation of common housekeeping genes in hepatocellular carcinoma. BMC Genomics. 8:243.

Chen X, et al. (2002) Gene expression patterns in human liver cancers. Mol. Biol. Cell 13:1929–39.

Delpuech O, et al. (2002). Identification, using cDNA macroarray analysis, of distinct gene expression profiles associated with pathological and virological features of hepatocellular carcinoma. Oncogene 21:2926–37.