Generation of gene-corrected isogenic control cell lines from a DYT1 dystonia patient iPSC line carrying a heterozygous GAG mutation in TOR1A gene

Stem Cell Research - Tập 62 - Trang 102807 - 2022
Masuma Akter1,2, Haochen Cui1, Yi-Hsien Chen3, Baojin Ding1
1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA
2Department of Biology, University of Louisiana at Lafayette, Lafayette, LA, 70503, USA
3Genome Engineering and iPSC Center (GEiC), Washington University in St Louis, MO 63110, USA

Tài liệu tham khảo

Akter M, Cui H, Chen YH, Ding B (2021) Generation of two induced pluripotent stem cell lines with heterozygous and homozygous GAG deletion in TOR1A gene from a healthy hiPSC line. Stem Cell Res 56, 102536. Akter M, Cui H, Sepehrimanesh M, Hosain MA, Ding B (2022) Generation of highly pure motor neurons from human induced pluripotent stem cells. STAR Protoc 3, 101223. Ding, 2021, Disease Modeling with Human Neurons Reveals LMNB1 Dysregulation Underlying DYT1 Dystonia, J. Neurosci., 41, 2024, 10.1523/JNEUROSCI.2507-20.2020 Goodchild, 2005, Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope, Neuron, 48, 923, 10.1016/j.neuron.2005.11.010 Wu J, Ren J, Luo H, Zuo X, Tang Y (2021) Generation of patient-specific induced pluripotent stem cell line (CSUi002-A) from a patient with isolated dystonia carrying TOR1A mutation. Stem Cell Res 53, 102277.