Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL

Stem Cell Research - Tập 31 - Trang 157-160 - 2018
Alyssa L. Gagne1,2, Jean Ann Maguire1,2, Shilpa Gandre-Babbe3, Stella T. Chou3, Sarah K. Tasian4, Mignon L. Loh5, Mitchell J. Weiss3,6, Paul Gadue1,2, Deborah L. French1,2
1Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, United States
2Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, United States
3Division of Hematology, The Children's Hospital of Philadelphia, United States
4Division of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, United States
5Department of Pediatrics, Benioff Children's Hospital and the Helen Diller Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, United States
6Department of Hematology, St. Jude Children's Research Hospital, United States

Tài liệu tham khảo

Gandre-Babbe, 2013, Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia, Blood, 121, 4925, 10.1182/blood-2013-01-478412 Loh, 2009, Mutations in CBL occur frequently in juvenile myelomonocytic leukemia, Blood, 114, 1859, 10.1182/blood-2009-01-198416 Somers, 2010, Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette, Stem Cells, 28, 1728, 10.1002/stem.495 Stieglitz, 2015, The genomic landscape of juvenile myelomonocytic leukemia, Nat. Genet., 47, 1326, 10.1038/ng.3400