General Approach to the Clinical Care of Solid Organ Transplant Recipients with COVID-19 Infection

citation_journal_title=Transplantation.; citation_title=Global transplantation COVID report March 2020; citation_author=C Ahn, H Amer, D Anglicheau, N Ascher, C Baan, B Bat-Ireedui; citation_volume=104; citation_publication_date=2020; citation_pages=1974-1983; citation_doi=10.1097/tp.0000000000003258; citation_id=CR1 citation_journal_title=Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg; citation_title=Early impact of COVID-19 on transplant center practices and policies in the United States; citation_author=BJ Boyarsky, T Po-Yu Chiang, WA Werbel, CM Durand, RK Avery, SN Getsin, KR Jackson, AB Kernodle, SE van Pilsum Rasmussen, AB Massie, DL Segev, JM Garonzik-Wang; citation_volume=20; citation_publication_date=2020; citation_pages=1809-1818; citation_doi=10.1111/ajt.15915; citation_id=CR2 Bromberg J, Baan C, Chapman J, Anegon I, Brennan DC, Chakera A, et al. The impact of COVID-19 on the state of clinical and laboratory research globally in transplantation in May 2020. Transplantation. 2020;Publish Ahead of Print. https://doi.org/10.1097/tp.0000000000003362 . citation_journal_title=J Clin Invest; citation_title=Kidney diseases in the time of COVID-19: major challenges to patient care; citation_author=H Rabb; citation_volume=130; citation_issue=6; citation_publication_date=2020; citation_pages=2749-2751; citation_doi=10.1172/jci138871; citation_id=CR4 Massie AB, Boyarsky BJ, Werbel WA, Bae S, Chow EK, Avery RK, et al. Identifying scenarios of benefit or harm from kidney transplantation during the COVID-19 pandemic: a stochastic simulation and machine learning study. Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg. 2020. https://doi.org/10.1111/ajt.16117 . citation_journal_title=Mayo Clin Proc; citation_title=Angiotensin-converting enzyme 2 and antihypertensives (angiotensin receptor blockers and angiotensin-converting enzyme inhibitors) in coronavirus disease 2019; citation_author=F Sanchis-Gomar, CJ Lavie, C Perez-Quilis, BM Henry, G Lippi; citation_volume=95; citation_publication_date=2020; citation_pages=1222-1230; citation_doi=10.1016/j.mayocp.2020.03.026; citation_id=CR6 citation_journal_title=Nat Rev Nephrol; citation_title=Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic; citation_author=AM South, L Tomlinson, D Edmonston, S Hiremath, MA Sparks; citation_volume=16; citation_publication_date=2020; citation_pages=1-3; citation_doi=10.1038/s41581-020-0279-4; citation_id=CR7 citation_journal_title=J Am Soc Nephrol; citation_title=Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology; citation_author=D Batlle, MJ Soler, MA Sparks, S Hiremath, AM South, PA Welling, S Swaminathan; citation_volume=31; citation_publication_date=2020; citation_pages=1380-1383; citation_doi=10.1681/asn.2020040419; citation_id=CR8 citation_journal_title=BMJ; citation_title=Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study; citation_author=AB Docherty, EM Harrison, CA Green, HE Hardwick, R Pius, L Norman; citation_volume=369; citation_publication_date=2020; citation_pages=m1985; citation_doi=10.1136/bmj.m1985; citation_id=CR9 citation_journal_title=Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg; citation_title=Infection in organ transplantation; citation_author=JA Fishman; citation_volume=17; citation_issue=4; citation_publication_date=2017; citation_pages=856-879; citation_doi=10.1111/ajt.14208; citation_id=CR10 Chaudhry ZS, Williams JD, Vahia A, Fadel R, Parraga Acosta T, Prashar R, et al. Clinical characteristics and outcomes of COVID-19 in solid organ transplant recipients: a case-control study. Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg. 2020. https://doi.org/10.1111/ajt.16188 . Roberts MB, Izzy S, Tahir Z, Al Jarrah A, Fishman JA, El Khoury J. COVID-19 in solid organ transplant recipients: dynamics of disease progression and inflammatory markers in ICU and non-ICU admitted patients. Transpl Infect Dis. 2020:e13407. https://doi.org/10.1111/tid.13407 . Kates OS, Haydel BM, Florman SS, Rana MM, Chaudhry ZS, Ramesh MS, et al. COVID-19 in solid organ transplant: a multi-center cohort study. Clin Infect Dis. 2020. https://doi.org/10.1093/cid/ciaa1097 . citation_journal_title=N Engl J Med; citation_title=Clinical characteristics of coronavirus disease 2019 in China; citation_author=WJ Guan, ZY Ni, Y Hu, WH Liang, CQ Ou, JX He, L Liu, H Shan, CL Lei, DSC Hui, B du, LJ Li, G Zeng, KY Yuen, RC Chen, CL Tang, T Wang, PY Chen, J Xiang, SY Li, JL Wang, ZJ Liang, YX Peng, L Wei, Y Liu, YH Hu, P Peng, JM Wang, JY Liu, Z Chen, G Li, ZJ Zheng, SQ Qiu, J Luo, CJ Ye, SY Zhu, NS Zhong; citation_volume=382; citation_issue=18; citation_publication_date=2020; citation_pages=1708-1720; citation_doi=10.1056/NEJMoa2002032; citation_id=CR14 citation_journal_title=Clin Transpl; citation_title=RNA respiratory viral infections in solid organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice; citation_author=O Manuel, M Estabrook; citation_volume=33; citation_issue=9; citation_publication_date=2019; citation_pages=e13511; citation_doi=10.1111/ctr.13511; citation_id=CR15 citation_journal_title=Clin Transpl; citation_title=Impact of solid organ transplantation and immunosuppression on fever, leukocytosis, and physiologic response during bacterial and fungal infections; citation_author=RG Sawyer, TD Crabtree, TG Gleason, JL Antevil, TL Pruett; citation_volume=13; citation_issue=3; citation_publication_date=1999; citation_pages=260-265; citation_doi=10.1034/j.1399-0012.1999.130307.x; citation_id=CR16 citation_journal_title=N Engl J Med; citation_title=Covid-19 and kidney transplantation; citation_author=E Akalin, Y Azzi, R Bartash, H Seethamraju, M Parides, V Hemmige, M Ross, S Forest, YD Goldstein, M Ajaimy, L Liriano-Ward, C Pynadath, P Loarte-Campos, PB Nandigam, J Graham, M le, J Rocca, M Kinkhabwala; citation_volume=382; citation_issue=25; citation_publication_date=2020; citation_pages=2475-2477; citation_doi=10.1056/NEJMc2011117; citation_id=CR17 citation_journal_title=Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg; citation_title=COVID-19 in solid organ transplant recipients: initial report from the US epicenter; citation_author=MR Pereira, S Mohan, DJ Cohen, SA Husain, GK Dube, LE Ratner, S Arcasoy, MM Aversa, LJ Benvenuto, DM Dadhania, S Kapur, LM Dove, RS Brown, RE Rosenblatt, B Samstein, N Uriel, MA Farr, M Satlin, CB Small, TJ Walsh, RP Kodiyanplakkal, BA Miko, JG Aaron, DS Tsapepas, JC Emond, EC Verna; citation_volume=20; citation_publication_date=2020; citation_pages=1800-1808; citation_doi=10.1111/ajt.15941; citation_id=CR18 Yi SG, Rogers AW, Saharia A, Aoun M, Faour R, Abdelrahim M, et al. Early experience with COVID-19 and solid organ transplantation at a US high-volume transplant center. Transplantation. 2020;Publish Ahead of Print. https://doi.org/10.1097/tp.0000000000003339 . citation_journal_title=Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg; citation_title=COVID-19 in solid organ transplant recipients: a single-center case series from Spain; citation_author=M Fernández-Ruiz, A Andrés, C Loinaz, JF Delgado, F López-Medrano, R San Juan, E González, N Polanco, MD Folgueira, A Lalueza, C Lumbreras, JM Aguado; citation_volume=20; citation_publication_date=2020; citation_pages=1849-1858; citation_doi=10.1111/ajt.15929; citation_id=CR20 citation_journal_title=J Am Soc Nephrol; citation_title=Early description of coronavirus 2019 disease in kidney transplant recipients in New York; citation_author=S Mohan; citation_volume=31; citation_publication_date=2020; citation_pages=1150-1156; citation_doi=10.1681/asn.2020030375; citation_id=CR21 citation_journal_title=Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg; citation_title=First experience of SARS-CoV-2 infections in solid organ transplant recipients in the Swiss transplant cohort study; citation_author=J Tschopp, AG L'Huillier, M Mombelli, NJ Mueller, N Khanna, C Garzoni, D Meloni, M Papadimitriou-Olivgeris, D Neofytos, HH Hirsch, MM Schuurmans, T Müller, T Berney, J Steiger, M Pascual, O Manuel, C Delden, P Amico, JD Aubert, V Banz, G Beldi, C Benden, C Berger, I Binet, PY Bochud, S Branca, H Bucher, T Carell, E Catana, Y Chalandon, S Geest, O Rougemont, M Dickenmann, M Duchosal, L Elkrief, T Fehr, S Ferrari-Lacraz, C Garzoni, PG Soccal, C Gaudet, E Giostra, D Golshayan, K Hadaya, J Halter, D Hauri, D Heim, C Hess, S Hillinger, HH Hirsch, G Hofbauer, U Huynh-Do, F Immer, R Klaghofer, M Koller, B Laesser, G Laube, R Lehmann, C Lovis, P Majno, O Manuel, HP Marti, PY Martin, M Martinelli, P Meylan, NJ Mueller, A Müller, T Müller, B Müllhaupt, M Pascual, J Passweg, K Posfay-Barbe, J Rick, E Roosnek, A Rosselet, S Rothlin, F Ruschitzka, U Schanz, S Schaub, A Schnyder, M Schuurmans, C Seiler, J Sprachta, S Stampf, C Steinack, J Steiger, G Stirnimann, C Toso, C van Delden, JP Venetz, J Villard, M Wick, M Wilhelm, P Yerly; citation_volume=20; citation_publication_date=2020; citation_pages=2876-2882; citation_doi=10.1111/ajt.16062; citation_id=CR22 citation_journal_title=Kidney Int; citation_title=A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia; citation_author=F Alberici, E Delbarba, C Manenti, L Econimo, F Valerio, A Pola, C Maffei, S Possenti, N Zambetti, M Moscato, M Venturini, S Affatato, M Gaggiotti, N Bossini, F Scolari; citation_volume=97; citation_issue=6; citation_publication_date=2020; citation_pages=1083-1088; citation_doi=10.1016/j.kint.2020.04.002; citation_id=CR23 citation_journal_title=Clin Infect Dis; citation_title=Clinical features of 69 cases with coronavirus disease 2019 in Wuhan, China; citation_author=Z Wang, B Yang, Q Li, L Wen, R Zhang; citation_volume=71; citation_publication_date=2020; citation_pages=769-777; citation_doi=10.1093/cid/ciaa272; citation_id=CR24 citation_journal_title=Lancet Infect Dis; citation_title=Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study; citation_author=H Shi, X Han, N Jiang, Y Cao, O Alwalid, J Gu, Y Fan, C Zheng; citation_volume=20; citation_issue=4; citation_publication_date=2020; citation_pages=425-434; citation_doi=10.1016/s1473-3099(20)30086-4; citation_id=CR25 citation_journal_title=J Clin Invest; citation_title=Clinical and immunological features of severe and moderate coronavirus disease 2019; citation_author=G Chen, D Wu, W Guo, Y Cao, D Huang, H Wang, T Wang, X Zhang, H Chen, H Yu, X Zhang, M Zhang, S Wu, J Song, T Chen, M Han, S Li, X Luo, J Zhao, Q Ning; citation_volume=130; citation_issue=5; citation_publication_date=2020; citation_pages=2620-2629; citation_doi=10.1172/jci137244; citation_id=CR26 citation_journal_title=Clin Infect Dis; citation_title=Prediction for progression risk in patients with COVID-19 pneumonia: the CALL score; citation_author=D Ji, D Zhang, J Xu, Z Chen, T Yang, P Zhao, G Chen, G Cheng, Y Wang, J Bi, L Tan, G Lau, E Qin; citation_volume=71; citation_publication_date=2020; citation_pages=1393-1399; citation_doi=10.1093/cid/ciaa414; citation_id=CR27 citation_journal_title=J Clin Virol; citation_title=Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19; citation_author=F Liu, L Li, M Xu, J Wu, D Luo, Y Zhu, BX Li, XY Song, X Zhou; citation_volume=127; citation_publication_date=2020; citation_pages=104370; citation_doi=10.1016/j.jcv.2020.104370; citation_id=CR28 citation_journal_title=J Thromb Haemost; citation_title=ISTH interim guidance on recognition and management of coagulopathy in COVID-19; citation_author=J Thachil, N Tang, S Gando, A Falanga, M Cattaneo, M Levi, C Clark, T Iba; citation_volume=18; citation_issue=5; citation_publication_date=2020; citation_pages=1023-1026; citation_doi=10.1111/jth.14810; citation_id=CR29 citation_journal_title=Lancet; citation_title=Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study; citation_author=F Zhou, T Yu, R Du, G Fan, Y Liu, Z Liu; citation_volume=395; citation_issue=10229; citation_publication_date=2020; citation_pages=1054-1062; citation_doi=10.1016/s0140-6736(20)30566-3; citation_id=CR30 citation_journal_title=Virus Res; citation_title=Co-infection with respiratory pathogens among COVID-2019 cases; citation_author=X Zhu, Y Ge, T Wu, K Zhao, Y Chen, B Wu, F Zhu, B Zhu, L Cui; citation_volume=285; citation_publication_date=2020; citation_pages=198005; citation_doi=10.1016/j.virusres.2020.198005; citation_id=CR31 ESC. ESC guidance for the diagnosis and management of CV disease during the COVID-19 pandemic. https://www.escardio.org/Education/COVID-19-and-Cardiology/ESC-COVID%2D%2DGuidance . Accessed 21 Apr 2020 citation_journal_title=J Infect; citation_title=A clinical risk score to identify patients with COVID-19 at high risk of critical care admission or death: An observational cohort study; citation_author=JB Galloway, S Norton, RD Barker, A Brookes, I Carey, BD Clarke, R Jina, C Reid, MD Russell, R Sneep, L Sugarman, S Williams, M Yates, J Teo, AM Shah, F Cantle; citation_volume=81; citation_publication_date=2020; citation_pages=282-288; citation_doi=10.1016/j.jinf.2020.05.064; citation_id=CR33 Fix OK, Hameed B, Fontana RJ, Kwok RM, McGuire BM, Mulligan DC, et al. Clinical best practice advice for hepatology and liver transplant providers during the COVID-19 pandemic: AASLD Expert Panel Consensus Statement. Hepatology. 2020. https://doi.org/10.1002/hep.31281 . citation_journal_title=J Hepatol; citation_title=COVID-19: abnormal liver function tests; citation_author=Q Cai, D Huang, H Yu, Z Zhu, Z Xia, Y Su, Z Li, G Zhou, J Gou, J Qu, Y Sun, Y Liu, Q He, J Chen, L Liu, L Xu; citation_volume=73; citation_publication_date=2020; citation_pages=566-574; citation_doi=10.1016/j.jhep.2020.04.006; citation_id=CR35 citation_journal_title=Kidney Int; citation_title=Kidney disease is associated with in-hospital death of patients with COVID-19; citation_author=Y Cheng, R Luo, K Wang, M Zhang, Z Wang, L Dong, J Li, Y Yao, S Ge, G Xu; citation_volume=97; citation_issue=5; citation_publication_date=2020; citation_pages=829-838; citation_doi=10.1016/j.kint.2020.03.005; citation_id=CR36 citation_journal_title=Lancet Respir Med; citation_title=Management of acute kidney injury in patients with COVID-19; citation_author=C Ronco, T Reis, F Husain-Syed; citation_volume=8; citation_publication_date=2020; citation_pages=738-742; citation_doi=10.1016/s2213-2600(20)30229-0; citation_id=CR37 citation_journal_title=Am J Physiol Ren Physiol; citation_title=Is the kidney a target of SARS-CoV-2?; citation_author=MA Martinez-Rojas, O Vega-Vega, NA Bobadilla; citation_volume=318; citation_issue=6; citation_publication_date=2020; citation_pages=F1454-F1f62; citation_doi=10.1152/ajprenal.00160.2020; citation_id=CR38 citation_journal_title=Thromb Res; citation_title=Incidence of thrombotic complications in critically ill ICU patients with COVID-19; citation_author=FA Klok, M Kruip, NJM Meer, MS Arbous, D Gommers, KM Kant; citation_volume=191; citation_publication_date=2020; citation_pages=145-147; citation_doi=10.1016/j.thromres.2020.04.013; citation_id=CR39 citation_journal_title=Lancet Haematol; citation_title=Coagulation abnormalities and thrombosis in patients with COVID-19; citation_author=M Levi, J Thachil, T Iba, JH Levy; citation_volume=7; citation_issue=6; citation_publication_date=2020; citation_pages=e438-ee40; citation_doi=10.1016/s2352-3026(20)30145-9; citation_id=CR40 citation_journal_title=Kidney Int; citation_title=Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China; citation_author=H Su, M Yang, C Wan, LX Yi, F Tang, HY Zhu, F Yi, HC Yang, AB Fogo, X Nie, C Zhang; citation_volume=98; citation_publication_date=2020; citation_pages=219-227; citation_doi=10.1016/j.kint.2020.04.003; citation_id=CR41 Lai CC, Wang CY, Hsueh PR. Co-infections among patients with COVID-19: the need for combination therapy with non-anti-SARS-CoV-2 agents? J Microbiol Immunol Infect. 2020. https://doi.org/10.1016/j.jmii.2020.05.013 . citation_journal_title=Intensive Care Med; citation_title=Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients; citation_author=JF Timsit, R Sonneville, AC Kalil, M Bassetti, R Ferrer, S Jaber, F Lanternier, CE Luyt, F Machado, M Mikulska, L Papazian, F Pène, G Poulakou, C Viscoli, M Wolff, L Zafrani, C van Delden; citation_volume=45; citation_issue=5; citation_publication_date=2019; citation_pages=573-591; citation_doi=10.1007/s00134-019-05597-y; citation_id=CR43 citation_journal_title=Clin Chim Acta; citation_title=Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): a meta-analysis; citation_author=G Lippi, M Plebani; citation_volume=505; citation_publication_date=2020; citation_pages=190-191; citation_doi=10.1016/j.cca.2020.03.004; citation_id=CR44 citation_journal_title=Acad Radiol; citation_title=Disposable isolation device to reduce COVID-19 contamination during CT scanning; citation_author=A Amalou, B Turkbey, S Xu, E Turkbey, P An, G Carrafiello, AM Ierardi, R Suh, H Amalou, BJ Wood; citation_volume=27; citation_publication_date=2020; citation_pages=1119-1125; citation_doi=10.1016/j.acra.2020.05.017; citation_id=CR45 citation_journal_title=Intensive Care Med; citation_title=Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic; citation_author=QY Peng, XT Wang, LN Zhang; citation_volume=46; citation_issue=5; citation_publication_date=2020; citation_pages=849-850; citation_doi=10.1007/s00134-020-05996-6; citation_id=CR46 citation_journal_title=Intensive Care Med; citation_title=Thoracic ultrasonography: a narrative review; citation_author=PH Mayo, R Copetti, D Feller-Kopman, G Mathis, E Maury, S Mongodi, F Mojoli, G Volpicelli, M Zanobetti; citation_volume=45; citation_issue=9; citation_publication_date=2019; citation_pages=1200-1211; citation_doi=10.1007/s00134-019-05725-8; citation_id=CR47 citation_journal_title=J Intern Med; citation_title=COVID-19 diagnosis and management: a comprehensive review; citation_author=G Pascarella, A Strumia, C Piliego, F Bruno, R Buono, F Costa; citation_volume=288; citation_publication_date=2020; citation_pages=192-206; citation_doi=10.1111/joim.13091; citation_id=CR48 citation_journal_title=Ann Intern Med; citation_title=The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application; citation_author=SA Lauer, KH Grantz, Q Bi, FK Jones, Q Zheng, HR Meredith, AS Azman, NG Reich, J Lessler; citation_volume=172; citation_issue=9; citation_publication_date=2020; citation_pages=577-582; citation_doi=10.7326/m20-0504; citation_id=CR49 citation_journal_title=Nat Med; citation_title=Temporal dynamics in viral shedding and transmissibility of COVID-19; citation_author=X He, EHY Lau, P Wu, X Deng, J Wang, X Hao, YC Lau, JY Wong, Y Guan, X Tan, X Mo, Y Chen, B Liao, W Chen, F Hu, Q Zhang, M Zhong, Y Wu, L Zhao, F Zhang, BJ Cowling, F Li, GM Leung; citation_volume=26; citation_issue=5; citation_publication_date=2020; citation_pages=672-675; citation_doi=10.1038/s41591-020-0869-5; citation_id=CR50 citation_journal_title=Int J Surg; citation_title=Diagnosis and treatment of coronavirus disease 2019 (COVID-19): laboratory, PCR, and chest CT imaging findings; citation_author=E Abbasi-Oshaghi, F Mirzaei, F Farahani, I Khodadadi, H Tayebinia; citation_volume=79; citation_publication_date=2020; citation_pages=143-153; citation_doi=10.1016/j.ijsu.2020.05.018; citation_id=CR51 CDC. Coronavirus (COVID-19). https://www.cdc.gov/coronavirus/2019-ncov . Accessed 25 Jun 2020 citation_journal_title=World Neurosurg; citation_title=Telemedicine for outpatient neurosurgical oncology care: lessons learned for the future during the COVID-19 pandemic; citation_author=LC Daggubati, DG Eichberg, ME Ivan, S Hanft, A Mansouri, RJ Komotar, RS D'Amico, BE Zacharia; citation_volume=139; citation_publication_date=2020; citation_pages=e859-e863; citation_doi=10.1016/j.wneu.2020.05.140; citation_id=CR53 citation_journal_title=Clin J Am Soc Nephrol; citation_title=Outpatient Management of the Kidney Transplant Recipient during the SARS-CoV-2 virus pandemic; citation_author=SE Gleeson, RN Formica, EP Marin; citation_volume=15; citation_publication_date=2020; citation_pages=892-895; citation_doi=10.2215/cjn.04510420; citation_id=CR54 citation_journal_title=J Clin Orthop Trauma; citation_title=Out patient department practices in orthopaedics amidst COVID-19: the evolving model; citation_author=H Lal, DK Sharma, MK Patralekh, VK Jain, L Maini; citation_volume=11; citation_issue=4; citation_publication_date=2020; citation_pages=700-712; citation_doi=10.1016/j.jcot.2020.05.009; citation_id=CR55 citation_journal_title=JHEP Rep; citation_title=Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper; citation_author=T Boettler, PN Newsome, MU Mondelli, M Maticic, E Cordero, M Cornberg, T Berg; citation_volume=2; citation_issue=3; citation_publication_date=2020; citation_pages=100113; citation_doi=10.1016/j.jhepr.2020.100113; citation_id=CR56 citation_journal_title=J Am Soc Nephrol; citation_title=Cell-free DNA and active rejection in kidney allografts; citation_author=RD Bloom, JS Bromberg, ED Poggio, S Bunnapradist, AJ Langone, P Sood, AJ Matas, S Mehta, RB Mannon, A Sharfuddin, B Fischbach, M Narayanan, SC Jordan, D Cohen, MR Weir, D Hiller, P Prasad, RN Woodward, M Grskovic, JJ Sninsky, JP Yee, DC Brennan; citation_volume=28; citation_issue=7; citation_publication_date=2017; citation_pages=2221-2232; citation_doi=10.1681/asn.2016091034; citation_id=CR57 citation_journal_title=Front Psych; citation_title=Psychological and psychopathological aspects of kidney transplantation: a systematic review; citation_author=C Pasquale, ML Pistorio, M Veroux, L Indelicato, G Biffa, N Bennardi; citation_volume=11; citation_publication_date=2020; citation_pages=106; citation_doi=10.3389/fpsyt.2020.00106; citation_id=CR58 citation_journal_title=Front Med; citation_title=Therapeutic algorithm for use of melatonin in patients with COVID-19; citation_author=RJ Reiter, P Abreu-Gonzalez, PE Marik, A Dominguez-Rodriguez; citation_volume=7; citation_publication_date=2020; citation_pages=226; citation_doi=10.3389/fmed.2020.00226; citation_id=CR59 citation_journal_title=Life Sci; citation_title=COVID-19: melatonin as a potential adjuvant treatment; citation_author=R Zhang, X Wang, L Ni, X Di, B Ma, S Niu; citation_volume=250; citation_publication_date=2020; citation_pages=117583; citation_doi=10.1016/j.lfs.2020.117583; citation_id=CR60 AST. 2019-nCoV (Coronavirus): Recommendations and guidance for organ donor testing https://www.myast.org/sites/default/files/internal/COVID19FAQDonorTesting05142020.pdf . Accessed 19 May 2020 citation_journal_title=Eur Urol; citation_title=Coronavirus disease 2019 pneumonia in immunosuppressed renal transplant recipients: a summary of 10 confirmed cases in Wuhan, China; citation_author=L Zhu, N Gong, B Liu, X Lu, D Chen, S Chen, H Shu, K Ma, X Xu, Z Guo, E Lu, D Chen, Q Ge, J Cai, J Jiang, L Wei, W Zhang, G Chen, Z Chen; citation_volume=77; citation_issue=6; citation_publication_date=2020; citation_pages=748-754; citation_doi=10.1016/j.eururo.2020.03.039; citation_id=CR62 citation_journal_title=Clin Infect Dis; citation_title=The natural history of influenza infection in the severely immunocompromised vs nonimmunocompromised hosts; citation_author=MJ Memoli, R Athota, S Reed, L Czajkowski, T Bristol, K Proudfoot, R Hagey, J Voell, C Fiorentino, A Ademposi, S Shoham, JK Taubenberger; citation_volume=58; citation_issue=2; citation_publication_date=2014; citation_pages=214-224; citation_doi=10.1093/cid/cit725; citation_id=CR63 citation_journal_title=J Heart Lung Transplant; citation_title=COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal; citation_author=HK Siddiqi, MR Mehra; citation_volume=39; citation_issue=5; citation_publication_date=2020; citation_pages=405-407; citation_doi=10.1016/j.healun.2020.03.012; citation_id=CR64 citation_journal_title=Intensive Care Med; citation_title=Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China; citation_author=Q Ruan, K Yang, W Wang, L Jiang, J Song; citation_volume=46; citation_issue=5; citation_publication_date=2020; citation_pages=846-848; citation_doi=10.1007/s00134-020-05991-x; citation_id=CR65 citation_journal_title=Lancet Respir Med; citation_title=Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations; citation_author=J Phua, L Weng, L Ling, M Egi, CM Lim, JV Divatia, BR Shrestha, YM Arabi, J Ng, CD Gomersall, M Nishimura, Y Koh, B du; citation_volume=8; citation_issue=5; citation_publication_date=2020; citation_pages=506-517; citation_doi=10.1016/s2213-2600(20)30161-2; citation_id=CR66 citation_journal_title=Emerg Med Pract; citation_title=Novel 2019 coronavirus SARS-CoV-2 (COVID-19): an updated overview for emergency clinicians; citation_author=AL Giwa, A Desai, A Duca; citation_volume=22; citation_issue=5; citation_publication_date=2020; citation_pages=1-28; citation_id=CR67 citation_journal_title=Jama.; citation_title=Association of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use with COVID-19 diagnosis and mortality; citation_author=EL Fosbøl, JH Butt, L Østergaard, C Andersson, C Selmer, K Kragholm, M Schou, M Phelps, GH Gislason, TA Gerds, C Torp-Pedersen, L Køber; citation_volume=324; citation_publication_date=2020; citation_pages=168-177; citation_doi=10.1001/jama.2020.11301; citation_id=CR68 citation_journal_title=Circ Res; citation_title=Association of Inpatient use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19; citation_author=P Zhang, L Zhu, J Cai, F Lei, JJ Qin, J Xie, YM Liu, YC Zhao, X Huang, L Lin, M Xia, MM Chen, X Cheng, X Zhang, D Guo, Y Peng, YX Ji, J Chen, ZG She, Y Wang, Q Xu, R Tan, H Wang, J Lin, P Luo, S Fu, H Cai, P Ye, B Xiao, W Mao, L Liu, Y Yan, M Liu, M Chen, XJ Zhang, X Wang, RM Touyz, J Xia, BH Zhang, X Huang, Y Yuan, R Loomba, PP Liu, H Li; citation_volume=126; citation_issue=12; citation_publication_date=2020; citation_pages=1671-1681; citation_doi=10.1161/circresaha.120.317134; citation_id=CR69 citation_journal_title=Rev Med Virol; citation_title=Effect of maintenance immunosuppressive drugs on virus pathobiology: evidence and potential mechanisms; citation_author=DC Brennan, JM Aguado, L Potena, AG Jardine, C Legendre, MD Säemann, NJ Mueller, P Merville, V Emery, B Nashan; citation_volume=23; citation_issue=2; citation_publication_date=2013; citation_pages=97-125; citation_doi=10.1002/rmv.1733; citation_id=CR70 citation_journal_title=Viruses.; citation_title=Suppression of coronavirus replication by cyclophilin inhibitors; citation_author=Y Tanaka, Y Sato, T Sasaki; citation_volume=5; citation_issue=5; citation_publication_date=2013; citation_pages=1250-1260; citation_doi=10.3390/v5051250; citation_id=CR71 citation_journal_title=J Am Soc Nephrol; citation_title=COVID-19 and calcineurin inhibitors: should they get left out in the storm?; citation_author=M Willicombe, D Thomas, S McAdoo; citation_volume=31; citation_issue=6; citation_publication_date=2020; citation_pages=1145-1146; citation_doi=10.1681/asn.2020030348; citation_id=CR72 citation_journal_title=Virus Res; citation_title=Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506; citation_author=J Carbajo-Lozoya, MA Müller, S Kallies, V Thiel, C Drosten, A Brunn; citation_volume=165; citation_issue=1; citation_publication_date=2012; citation_pages=112-117; citation_doi=10.1016/j.virusres.2012.02.002; citation_id=CR73 citation_journal_title=Nat Rev Nephrol; citation_title=COVID-19: implications for immunosuppression in kidney disease and transplantation; citation_author=A Kronbichler, P Gauckler, M Windpessl, J Il Shin, V Jha, BH Rovin, R Oberbauer; citation_volume=16; citation_issue=7; citation_publication_date=2020; citation_pages=365-367; citation_doi=10.1038/s41581-020-0305-6; citation_id=CR74 Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, et al. Dexamethasone in hospitalized patients with Covid-19-preliminary report. N Engl J Med. 2020. https://doi.org/10.1056/NEJMoa2021436 . citation_journal_title=Transplantation.; citation_title=Impact of prophylactic versus preemptive valganciclovir on long-term renal allograft outcomes; citation_author=ML Spinner, G Saab, E Casabar, LJ Bowman, GA Storch, DC Brennan; citation_volume=90; citation_issue=4; citation_publication_date=2010; citation_pages=412-418; citation_doi=10.1097/TP.0b013e3181e81afc; citation_id=CR76 citation_journal_title=Expert Rev Anti-Infect Ther; citation_title=Prevention and management of cytomegalovirus infection in solid-organ transplantation; citation_author=K Mwintshi, DC Brennan; citation_volume=5; citation_issue=2; citation_publication_date=2007; citation_pages=295-304; citation_doi=10.1586/14787210.5.2.295; citation_id=CR77 citation_journal_title=Clin Infect Dis; citation_title=Community-acquired respiratory viruses are a risk factor for chronic lung allograft dysfunction; citation_author=M Peghin, I Los-Arcos, HH Hirsch, G Codina, V Monforte, C Bravo, C Berastegui, A Jauregui, L Romero, E Cabral, R Ferrer, J Sacanell, A Román, O Len, J Gavaldà; citation_volume=69; citation_issue=7; citation_publication_date=2019; citation_pages=1192-1197; citation_doi=10.1093/cid/ciy1047; citation_id=CR78 citation_journal_title=J Heart Lung Transplant; citation_title=Respiratory viral infection in lung transplantation induces exosomes that trigger chronic rejection; citation_author=M Gunasekaran, S Bansal, R Ravichandran, M Sharma, S Perincheri, F Rodriguez, R Hachem, CE Fisher, AP Limaye, A Omar, MA Smith, RM Bremner, T Mohanakumar; citation_volume=39; citation_issue=4; citation_publication_date=2020; citation_pages=379-388; citation_doi=10.1016/j.healun.2019.12.009; citation_id=CR79 citation_journal_title=J Am Soc Nephrol; citation_title=Polyomavirus reactivation and immune responses to kidney-specific self-antigens in transplantation; citation_author=ME Seifert, M Gunasekaran, TA Horwedel, R Daloul, GA Storch, T Mohanakumar, DC Brennan; citation_volume=28; citation_issue=4; citation_publication_date=2017; citation_pages=1314-1325; citation_doi=10.1681/asn.2016030285; citation_id=CR80 citation_journal_title=Am J Transplant Off J Am Soc Transplant Am Soc Transplant Surg; citation_title=BK-virus and the impact of pre-emptive immunosuppression reduction: 5-year results; citation_author=KL Hardinger, MJ Koch, DJ Bohl, GA Storch, DC Brennan; citation_volume=10; citation_issue=2; citation_publication_date=2010; citation_pages=407-415; citation_doi=10.1111/j.1600-6143.2009.02952.x; citation_id=CR81 citation_journal_title=Isr Med Assoc J; citation_title=Serum vitamin D levels in kidney transplant recipients: the importance of an immunosuppression regimen and sun exposure; citation_author=O Eyal, M Aharon, R Safadi, MD Elhalel; citation_volume=15; citation_issue=10; citation_publication_date=2013; citation_pages=628-633; citation_id=CR82 citation_journal_title=Rev Endocr Metab Disord; citation_title=Current evidence on vitamin D deficiency and kidney transplant: what’s new?; citation_author=G Sarno, R Nappi, B Altieri, G Tirabassi, E Muscogiuri, G Salvio, SA Paschou, A Ferrara, E Russo, D Vicedomini, C Vincenzo, A Vryonidou, S Della Casa, G Balercia, F Orio, P de Rosa; citation_volume=18; citation_issue=3; citation_publication_date=2017; citation_pages=323-334; citation_doi=10.1007/s11154-017-9418-z; citation_id=CR83 Kalluri HV, Sacha LM, Ingemi AI, Shullo MA, Johnson HJ, Sood P, et al. Low vitamin D exposure is associated with higher risk of infection in renal transplant recipients. Clin Transpl. 2017;31(5). https://doi.org/10.1111/ctr.12955 . citation_journal_title=Transplantation.; citation_title=The association of 25-hydroxyvitamin D levels with late cytomegalovirus infection in kidney transplant recipients: the Wisconsin Allograft Recipient Database; citation_author=BC Astor, A Djamali, DA Mandelbrot, S Parajuli, ML Melamed; citation_volume=103; citation_issue=8; citation_publication_date=2019; citation_pages=1683-1688; citation_doi=10.1097/tp.0000000000002672; citation_id=CR85 Pham H, Rahman A, Majidi A, Waterhouse M, Neale RE. Acute respiratory tract infection and 25-hydroxyvitamin D concentration: a systematic review and meta-analysis. Int J Environ Res Public Health. 2019;16(17). https://doi.org/10.3390/ijerph16173020 . citation_journal_title=Endocr Connect; citation_title=Vitamin D and critical illness: what endocrinology can learn from intensive care and vice versa; citation_author=K Amrein, A Papinutti, E Mathew, G Vila, D Parekh; citation_volume=7; citation_issue=12; citation_publication_date=2018; citation_pages=R304-Rr15; citation_doi=10.1530/ec-18-0184; citation_id=CR87 citation_journal_title=J Clin Transl Endocrinol; citation_title=High dose vitamin D administration in ventilated intensive care unit patients: a pilot double blind randomized controlled trial; citation_author=JE Han, JL Jones, V Tangpricha, MA Brown, LAS Brown, L Hao; citation_volume=4; citation_publication_date=2016; citation_pages=59-65; citation_doi=10.1016/j.jcte.2016.04.004; citation_id=CR88 citation_journal_title=N Engl J Med; citation_title=Early high-dose vitamin D(3) for critically ill, vitamin D-deficient patients; citation_author=AA Ginde, RG Brower, JM Caterino, L Finck, VM Banner-Goodspeed, CK Grissom; citation_volume=381; citation_issue=26; citation_publication_date=2019; citation_pages=2529-2540; citation_doi=10.1056/NEJMoa1911124; citation_id=CR89 citation_journal_title=Int Rev Immunol; citation_title=Can melatonin reduce the severity of COVID-19 pandemic?; citation_author=A Shneider, A Kudriavtsev, A Vakhrusheva; citation_volume=39; citation_issue=4; citation_publication_date=2020; citation_pages=153-162; citation_doi=10.1080/08830185.2020.1756284; citation_id=CR90 citation_journal_title=Ther Clin Risk Manag; citation_title=Current approaches in the grading and management of cytokine release syndrome after chimeric antigen receptor T-cell therapy; citation_author=LL Riegler, GP Jones, DW Lee; citation_volume=15; citation_publication_date=2019; citation_pages=323-335; citation_doi=10.2147/tcrm.s150524; citation_id=CR91 citation_journal_title=Nature.; citation_title=Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome; citation_author=V Staedtke, RY Bai, K Kim, M Darvas, ML Davila, GJ Riggins, PB Rothman, N Papadopoulos, KW Kinzler, B Vogelstein, S Zhou; citation_volume=564; citation_issue=7735; citation_publication_date=2018; citation_pages=273-277; citation_doi=10.1038/s41586-018-0774-y; citation_id=CR92 Vogelstein JT, Powell M, Koenecke A, Xiong R, Fischer N, Huq S, et al. Alpha-1 adrenergic receptor antagonists for preventing acute respiratory distress syndrome and death from cytokine storm syndrome. ArXiv. 2020. citation_journal_title=J Clin Invest; citation_title=Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists; citation_author=MF Konig, M Powell, V Staedtke, RY Bai, DL Thomas, N Fischer, S Huq, AM Khalafallah, A Koenecke, R Xiong, B Mensh, N Papadopoulos, KW Kinzler, B Vogelstein, JT Vogelstein, S Athey, S Zhou, C Bettegowda; citation_volume=130; citation_issue=7; citation_publication_date=2020; citation_pages=3345-3347; citation_doi=10.1172/jci139642; citation_id=CR94