Gene targeting of chemokines and their receptors
Tài liệu tham khảo
Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, Mac Dermott RP, Podolsky DK, Reinecker HC (2000) Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK 1.1+ lymphocyte associated Th2-type immune response in the intestine. J Immunol 164:6303
Boisvert WA, Curtiss LK, Terkeltaub RA (2000) Interleukin-8 and its receptor CXCR2 in atherosclerosis. Immunol Res 21:129
Boring L, Gosling J, Chensue SW, Kunkel SL, Farese RV Jr, Broxmeyer HE, Charo IF (1997) Impaired monocyte migration and reduced type 1 (Th 1) cytokine responses in CC chemokine receptor 2 knock out mice. J Clin Invest 100:2552
Boring L, Gosling J, Cleary M, Charo IF (1998) Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394:894
Broxmeyer HE, Cooper S, Hangoc G, Gao JL, Murphy PM (1999) Dominant myelopoietic effector functions mediated by chemokine receptor CCR1. J Exp Med 189:1987
Cacalano G, Lee J, Kikly K, Ryan AM, Pitts-Meek S, Hultgren B, Wood WI, Moore MW (1994) Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homologue. Science 265:682
Chvatchko Y, Hoogewerf AJ, Meyer A, Alouani S, Juillard P, Buser R, Conquet F, Proudfoot AE, Wells TN, Power CA (2000) A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock. J Exp Med 191:1755
Cook DN, Beck MA, Coffman TM, Kirby SL, Sheridan JF, Pragnell IB, Smithies O (1995) Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science 269:1583
Cook DN, Prosser DM, Forster R, Zhang J, Kuklin NA, Abbondanzo SJ, Niu XD, Chen SC, Manfra DJ, Wiekowski MT, Sullivan LM, Smith SR, Greenberg HB, Narula SK, Lipp M, Lira SA (2000) CCR6 mediates dendritic cell localization, lymphocyte homeostasis and immune responses in mucosal tissue. Immunity 12:495
Dawson TC, Beck MA, Kuziel WA, Henderson F, Maeda N (2000) Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus. Am J Pathol 156:1951
Dawson TC, Kuziel WA, Osahar TA, Maeda N (1999) Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis 143:205
Forster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M (1996) A putative chemokine receptor, BLR1 directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037
Forster R, Schubel A, Breitfeld D, Kremmer E, Renner-Muller I, Wolf E, Lipp M (1999) CCR7 coordinates the primary immune response by establishing functional movement in secondary lymphoid organs. Cell 99:23
Fuentes ME, Durham SK, Swerdel MR, Lewin AC, Barton DS, Megill JR, Bravo R, Lira S (1995) Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. J Immunol 155:5769
Gao JL, Wynn TA, Chang Y, Lee EJ, Broxmeyer HE, Cooper S, Tiffany HL, Westphal H, Kwon-Chung J, Murphy P (1997) Impaired host defense, hematopoiesis, granulomatous inflammation and type 1 - type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med 185:1959
Gao W, Topham PS, King JA, Smiley ST, Csizmadia V, Lu B, Gerard CJ, Hancock WW (2000) Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic allograft rejection. J Clin Invest 105:35
Gerard C, Frossard JL, Bhatia M, Saluja A, Gerard N, Lu B, Steer M (1997) Targeted disruption of the B chemokine receptor CCR 1 protects against pancreatitis-associated lung injury. J Clin Invest 100:2022
Gosling J, Slaymaker GuL, Tsen S, Zlot CH, Young SG, Rollins BJ, Charo IF (1999) MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J Clin Invest 103:773
Grewal IS, Rutledge BJ, Fiorillo JA, Gu L, Gladue RP, Flavell RA, Rollins BJ (1997) Transgenic monocyte chemoattractant protein-1 (MCP-1) in pancreatic islets produces monocyte-rich insulitis without diabetes: abrogation by a second transgene expressing systemic MCP-1. J Immunol 159:401
Gu L, Okada Y, Clinton SK, Gerard C, Sukhora GK, Libby P, Rollins BJ (1998) Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 2 (2):275
Gunn MD, Nelken NA, Liao X, Williams LT (1997) Monocyte chemottractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation. J Immunol 158:376
Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, Williams LT (1998) A B-cell homing chemo-kine made in lymphoid follicles activates Burkitt’s lymphoma receptor-1. Nature 391:799
Hogaboam CM, Bone-Larson CL, Steinhauser ML, Matsukawa A, Gosling J, Boring L, Charo IF, Simpson KJ, Lukacs NW, Kunkel SL (2000) Exaggerated hepatic injury due to acetaminophen challenge in mice lacking C-C chemokine receptor 2. Am J Pathol 156:1245
Hogan SP, Mishra A, Brandt EB, Foster PS, Rothenberg ME (2000) A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy. Proc Natl Acad Sci USA 97:6681
Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie O (1997) The T cell directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J Biol Chem 272:15036
Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie O, Gray PW (1998) Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. J Biol Chem 273:1764
Kolattukudy PE, Quach T, Bergese S, Brekenridge S, Hensley J, Altschuld R, Gordillo G, Klenotic S, Orosz C, Parker-Thomburg J (1998) Myocarditis induced by targeted expression of the MCP-1 gene in murine cardiac muscle. Am J Pathol 152:101
Kurihara T, Warr G, Loy J, Bravo R (1997) Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J Exp Med 186:1757
Kuziel WA Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N (1997) Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci USA 94:12053
Legler DF, Loetscher M, Roos RS, Clark-Lewis 1, Baggiolini M, Moser B (1998) B cell attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med 187:655
Lira SA, Fuentes ME, Strieter RM, Durham SK (1997) Transgenic methods to study chemokine function in lung and central nervous system. Methods Enzymol 287:304
Lira SA Zalamea P, Heinrich JN, Fuentes ME, Carrasco D, Lewin AC, Barton DS, Durham S, Bravo R (1994) Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells. J Exp Med 180:2039
Long G, Tseng S, Homer RM, Tam C, Loda M, Rollins BJ (2000) Control of Th2 polarization by the chemokine monocyte chemoattractant protein-1. Nature 404:407
Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ (1998) Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein-1 deficient mice. J Exp Med 187:601
Luster AD, Cardiff RD, Mac Lean JA, Crowe K, Granstein RD (1998) Delayed wound healing and disorganised neovascularisation in transgenic mice expressing the IP-10 chemokine. Proc Assoc Am Physicians 110:183
Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, Bronson RT, Springer TA (1998) Impaired B-lymphopoiesis, myelopoiesis and derailed cerebellar neuron migration in CXCR4 and SDF-1-deficient mice. Proc Natl Acad Sci USA 95:9448
Mehrad B, Strieter RM, Moore TA, Tsai WC, Lira SA, Standiford TJ (1999) CXC chemokine recep-tor-2 ligands are necessary components of neutrophil mediated host defense in invasive pulmonary aspergillosis. J Immunol 163:6086
Mishra A, Hogan SP, Lee JJ, Foster PS, Rothenberg ME (1999) Fundamental signals that regulate eosinophil homing to the gastrointestinal tract. J Clin Invest 103:1719
Moore TA, Newstead MW, Streiter RM, Mehrad B, Beaman BL, Standiford TJ (2000) Bacterial clearance and survival are dependent on CXC chemokine receptor-2 ligands in a murine model of pulmonary Nocardia asteroides. J Immunol 164:908
Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y, Yoshida N, Kikutani H, Kishimoto T (1996) Defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382:635
Nagira M, Imai T, Hieshima K, Kusada J, Ridanpaa M, Takagi S, Nishimura M, Kakizaki M, Nomigama H, Yoshie O (1997) Molecular cloning of a novel human CC chemokine secondary lymphoid tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9pl3. J Biol Chem 272:19518
Nakamura K, Williams IR, Kupper TS (1995) Keratinocyte derived monocyte chemoattractant protein-1 (MCP-1): analysis in a transgenic model demonstrates MCP-1 can recruit dendritic and langer-hans cells to skin. J Invest Dermatol 105:635
Rothenberg ME, Mac Lean JA, Pearlman E, Luster AD, Leder P (1997) Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophils. J Exp Med 185:785
Rutledge BJ, Rayburn H, Rosenberg R, North RJ, Gladue RP, Corless CL, Rollins BJ (1995) High level monocyte chemoattractant protein-1 expression in transgenic mice increases their susceptibility to intracellular pathogens. J Immunol 155:4838
Sato N, Kuziel WA, Melby PC, Reddick RL, Kostecki V, Zhao W, Maeda N, Ahuja SK, Ahuja SS (1999) Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice. J Immunol 163:5519
Smithies O, Gregg RG, Boggs SS, Koralewski MA, Kucherlapati RS (1985) Insertion of DNA sequences into the human chromosomal B-globulin locus by homologous recombination. Nature 317:230
Tachibana K, Hirota S, Iizasa H, Yoshida H, Kawabata K, Kataoka Y, Kitamura Y, Matsushima K, Yoshida N, Nishikawa S, Kishimoto T, Nagasawa T (1998) The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393:591
Tani M, Fuentes ME, Peterson JW, Trapp BD, Durham SK, Loy JK, Bravo R, Ransohoff RM, Lira SA (1996) Neutrophil infiltration, glial reaction and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J Clin Invest 98:529
Tophain PS, Csizmadia V, Soler D, Hines D, Gerard CJ, Salant DJ, Hancock WW (1999) Lack of chemokine receptor CCRI enhances Thl responses and glomerular injury during nephrotic nephritis. J Clin Invest 104:1549
Tran EH, Kuziel WA, Owens T (2000) Induction of experimental autoimmune encephalomyelitis in C57BL/6 mice deficient in either the chemokine macrophage inflammatory protein-1 alpha or its CCR5 receptor. Eur J Immunol 30:1410
Tsai WC, Strieter RM, Mehrad B, Newstead MW, Zeng X, Standiford TJ (2000) CXC chemokine receptor CXCR2 is essential for protective innate host response in murine Pseudomonas aeruginosa pneumonia. Infect Immun 68:4289
Tsai WC, Strieter RM, Wilkowski JM, Bucknell KA, Burdick MD, Lira SA, Standiford TJ (1998) Lung specific transgenic expression of KC enhances resistance to Klebsiella pneumoniae in mice. J Immunol 161:2435
Voigt I, Camacho SA, Boer BA de, Lipp M, Forster R, Berek C (2000) CXCR5 deficient mice develop functional germinal centers in the splenic T cell zone. Eur J Immunol 30:560
Yang Y, Loy J, Ryseck RP, Carrasco D, Bravo R (1998) Antigen induced eosinophilic lung inflammation develops in mice deficient in chemokine eotaxin. Blood 92:3912
Yoshida R, Imai T, Hieshima K, Kusada J, Baba M, Kitaura M, Nishmura M, Kakizaki M, Nomiyama H, Yoshie O (1997) Molecular cloning of a novel CC chemokine EBII ligand chemokine that is a specific functional ligand for EBII, CCR7. J Biol Chem 272:13803
Yoshida R, Nagira M, Kitura M, Imagawa N, Imai T, Yoshie O (1998) Secondary lymphoid tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. J Biol Chem 272:2718
Zhang S, Youn BS, Gao JL, Murphy PM, Kwon BS (1999) Differential effects of leukotactin-1 and macrophage inflammatory protein-1 alpha on neutrophils mediated by CCR 1. J Immunol 162:4938
Zhou Y, Kurihara T, Ryseck RP, Yang Y, Ryan C, Loy J, Warr G, Bravo RT (1998) Impaired macrophage function and enhanced T cell dependent immune réponse in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol 160:4018
Zou YR, Kottmann AH, Kuroda M, Taniuchi 1, Littman DR (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393:595
