Gene for lipoamide dehydrogenase maps to human chromosome 7
Tóm tắt
The gene for lipoamide dehydrogenase (LD) has been assigned to human chromosome 7 based on filter hybridization analysis of genomic DNA from rodent-human somatic cell hybrids using a cDNA probe for human LD. No indication of multiple copies of the gene was found, in accordance with previous evidence that LD in the pyruvate, α-ketoglutarate, and branched chain α-ketoacid dehydrogenase complexes is genetically as well as biochemically identical.
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