Gene Therapy Progress and Prospects: Nonviral vectors

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Li S, Ma Z . Nonviral gene therapy Curr Gene Ther 2001 1: 201–226

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Drabick JJ et al. Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization Mol Ther 2001 3: 249–255

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Tamura T et al. Intratumoral delivery of interleukin 12 expression plasmids with in vivo electroporation is effective for colon and renal cancer Hum Gene Ther 2001 12: 1265–1276

Liu F, Huang L . A syringe electrode device for simultaneous injection of DNA and electrotransfer Mol Ther 2002 5: 323–328

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Lin MT, Pulkkinen L, Uitto J, Yoon K . The gene gun: current application in cutaneous gene therapy Int J Dermatol 2000 39: 161–170

Davidson JM, Krieg T, Eming SA . Particle-mediated gene therapy of wounds Wound Repair Regen 2000 8: 452–459

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Kuriyama S et al. Particle-mediated gene transfer into murine livers using a newly developed gene gun Gene Ther 2000 7: 1132–1136

Yoshida S et al. Direct immunization of malaria DNA vaccine into the liver by gene gun protects against lethal challenge of Plasmodium berghei sporozoite Biochem Biophys Res Commun 2000 271: 107–115

Newman CM, Lawrie A, Brisken AF, Cumberland DC . Ultrasound gene therapy: on the road from concept to reality Echocardiography 2001 18: 339–347

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Taniyama Y et al. Local delivery of plasmid DNA into rat carotid artery using ultrasound Circulation 2002 105: 1233–1239

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Unger EC, Hersh E, Vannan M, McCreery T . Gene delivery using ultrasound contrast agents Echocardiography 2001 18: 355–361

Lawrie A et al. Microbubble-enhanced ultrasound for vascular gene delivery Gene Ther 2000 7: 2023–2027

Song J et al. Influence of injection site, microvascular pressure and ultrasound variables on microbubble-mediated delivery of microspheres to muscle J Am Coll Cardiol 2002 39: 726–731

Shohet RV et al. Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium Circulation 2000 101: 2554–2556

Endoh M et al. Fetal gene transfer by intrauterine injection with microbubble-enhanced ultrasound Mol Ther 2002 5; 501–508

Budker V et al. Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process J Gene Med 2000 2: 76–88

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Liu F, Huang L . Noninvasive gene delivery to the liver by mechanical massage Hepatology 2002 35: 1314–1319

Zhang G et al. Efficient expression of naked DNA delivered intraarterially to limb muscles of nonhuman primates Hum Gene Ther 2001 12: 427–438

Liu F, Huang L . Improving plasmid DNA-mediated liver gene transfer by prolonging its retention in the hepatic vasculature J Gene Med 2001 3: 569–576

Liu F, Nishikawa M, Clemens PR, Huang L . Transfer of full-length Dmd to the diaphragm muscle of Dmd(mdx/mdx) mice through systemic administration of plasmid DNA Mol Ther 2001 4: 45–51

Dauty E, Remy JS, Blessing T, Behr JP . Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture J Am Chem Soc 2001 123: 9227–9234

McKenzie DL, Kwok KY, Rice KG . A potent new class of reductively activated peptide gene delivery agents J Biol Chem 2000 275: 9970–9977

Park Y, Kwok KY, Boukarim C, Rice KG . Synthesis of sulfhydryl cross-linking poly(ethylene glycol)-peptides and glyco-peptides as carriers for gene delivery Bioconjug Chem 2002 13: 232–239

Wightman L et al. Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo J Gene Med 2001 3: 362–372

Lim YB et al. Biodegradable polyester, poly[α-(4-aminobutyl)-L-glycolic acid], as a non-toxic gene carrier Pharm Res 2000 17: 811–816

Koh JJ et al. Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice Gene Ther 2000 7: 2099–2104

Maheshwari A et al. Soluble biodegradable polymer-based cytokine gene delivery for cancer treatment Mol Ther 2000 2: 121–130

Ahn CH, Chae SY, Bae YH, Kim SW . Biodegradable poly(ethylenimine) for plasmid DNA delivery J Control Release 2002 80: 273–282

Wang J, Mao HQ, Leong KW . A novel biodegradable gene carrier based on polyphosphoester J Am Chem Soc 2001 123: 9480–9581

Kurisawa M, Yokoyama M, Okano T . Gene expression control by temperature with thermo-responsive polymeric gene carriers J Control Release 2000 69: 127–137

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Jeong B, Bae YH, Kim SW . Drug release from biodegradable injectable thermosensitive hydrogel of PEG–PLGA–PEG triblock copolymers J Control Release 2000 63: 155–163

Harada-Shiba M et al. Polyion complex micelles as vectors in gene therapy – pharmacokinetics and in vivo gene transfer Gene Ther 2002 9: 407–414

Turk MJ, Reddy JA, Chmielewski JA, Low PS . Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs Biochim Biophys Acta 2002 1559: 56–68

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Bremner KH, Seymour LW, Pouton CW . Harnessing nuclear localization pathways for transgene delivery Curr Opin Mol Ther 2001 3: 170–177

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Cartier R, Reszka R . Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems Gene Ther 2002 9: 157–167

Tousignant JD et al. Comprehensive analysis of the acute toxicities induced by systemic administration of cationic lipid:plasmid DNA complexes in mice Hum Gene Ther 2000 11: 2493–2513

Yew NS et al. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs Mol Ther 2000 1: 255–262

Hofman CR et al. Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activity Gene Ther 2001 8: 71–74

Li S et al. Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody Am J Physiol Lung Cell Mol Physiol 2000 278L: 504–511

Tan Y et al. Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity Mol Ther 2001 3: 673–682

Miao CH et al. Inclusion of the hepatic locus control region, an intron, and untranslated region increases and stabilizes hepatic factor IX gene expression in vivo but not in vitro Mol Ther 2000 1: 522–532

Chen ZY et al. Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver Mol Ther 2001 3: 403–410

Maruyama-Tabata H et al. Effective suicide gene therapy in vivo by EBV-based plasmid vector coupled with polyamidoamine dendrimer Gene Ther 2000 7: 53–60

Tomiyasu K et al. Direct intra-cardiomuscular transfer of beta2-adrenergic receptor gene augments cardiac output in cardiomyopathic hamsters Gene Ther 2000 7: 2087–2093

Cui FD et al. Highly efficient gene transfer into murine liver achieved by intravenous administration of naked Epstein–Barr virus (EBV)-based plasmid vectors Gene Ther 2001 8: 1508–1513

Stoll SM et al. Epstein–Barr virus/human vector provides high-level, long-term expression of α1-antitrypsin in mice Mol Ther 2001 4: 122–129

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Olivares EC, Hollis RP, Calos MP . Phage R4 integrase mediates site-specific integration in human cells Gene 2001 278: 167–176

Sclimenti CR, Thyagarajan B, Calos MP . Directed evolution of a recombinase for improved genomic integration at a native human sequence Nucleic Acids Res 2001 29: 5044–5051

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