Gemini Surfactants Templated Mesoporous Silica Microparticles: from Solid to Hollow Mesoporous Spheres

Chinese Journal of Chemistry - Tập 35 Số 11 - Trang 1706-1710 - 2017
Min Li1, Chun Zhang1, Xiangliang Yang1
1College of Life Science and Technology, Huazhong University of Science and Technology, and National Engineering Research Center for Nanomedicine, Wuhan, Hubei 430074, China

Tóm tắt

We synthesized a series of mesoporous silica microparticles (MSs) using cationic gemini surfactants C14–2‐n (n = 2, 6, 10, 14) as templates. The porous structures and pore size of these MSs can be tuned by varying the length of alkyl chain in gemini surfactant templates. These MSs showed effective doxorubicin (DOX) loading and a pH‐responsive drug release characteristics. These results indicate that the MSs, especially the hollow mesoporous silica nanoparticles, have great potential for biomedical applications.

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Thông tin xuất bản

Chinese Journal of Chemistry

Tập 35 Số 11

1706-1710

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