Gelatin hydrogel impregnated with platelet-rich plasma releasate promotes angiogenesis and wound healing in murine model

Journal of Artificial Organs - Tập 18 Số 1 - Trang 64-71 - 2015
Priscilla Valentin Notodihardjo1, Naoki Morimoto2, Natsuko Kakudo1, Makoto Matsui3, Michiharu Sakamoto4, Pham Hieu Liem4, Kenji Suzuki1, Yasuhiko Tabata3, Kenji Kusumoto1
1Department of Plastic and Reconstructive Surgery, Kansai Medical University, Hirakata, Japan
2Department of Plastic and Reconstructive Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan
3Department of Biomaterial, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
4Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004;62:489–96.

Kakudo N, Minakata T, Mitsui T, et al. Proliferation-promoting effect of platelet-rich plasma on human adipose-derived stem cells and human dermal fibroblasts. Plast Reconstr Surg. 2008;122:1352–60.

Morimoto N, Yoshimura K, Niimi M, et al. Novel collagen/gelatin scaffold with sustained release of basic fibroblast growth factor: clinical trial for chronic skin ulcers. Tissue Eng Part A. 2013;19:1931–40.

Ito R, Morimoto N, Pham LH, et al. Efficacy of the controlled release of concentrated platelet lysate from a collagen/gelatin scaffold for dermis-like tissue regeneration. Tissue Eng Part A. 2013;19:140–1398.

Ozeki M, Tabata Y. Promoted growth of murine hair follicles through controlled release of basic fibroblast growth factor. Tissue Eng. 2002;8:359–66.

Hong L, Tabata Y, Miyamoto S, et al. Bone regeneration at rabbit skull defects treated with transforming growth factor-beta1 incorporated into hydrogels with different levels of biodegradability. J Neurosurg. 2000;92:315–25.

Kanematsu A, Yamamoto S, Ozeki M, et al. Collagenous matrices as release carriers of exogenous growth factors. Biomaterials. 2004;25:4513–20.

Matsui M, Tabata Y. Enhanced angiogenesis by multiple release of platelet-rich plasma contents and basic fibroblast growth factor from gelatin hydrogels. Acta Biomater. 2012;8:1792–801.

Ishida K, Kuroda R, Miwa M, et al. The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng. 2007;13:1103–12.

Nagae M, Ikeda T, Mikami Y, et al. Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres. Tissue Eng. 2007;13:147–58.

Tabata Y, Nagano A, Ikada Y. Biodegradation of hydrogel carrier incorporating fibroblast growth factor. Tissue Eng. 1999;5:127–38.

Bir SC, Esaki J, Marui A, et al. Angiogenic properties of sustained release platelet-rich plasma: characterization in vitro and in the ischemic hind limb of the mouse. J Vasc Surg. 2009;50:870–9.

Galiano RD, Michaels J, Dobryansky M, et al. Quantitative and reproducible murine model of excisional wound healing. Wound Repair Regen. 2004;12:485–92.

Liem PH, Morimoto N, Ito R, et al. Treating a collagen scaffold with a low concentration of nicotine promoted angiogenesis and wound healing. J Surg Res. 2013;15:353–61.

Martinez-Zapata MJ, Marti-Carvajal A, Solà I. Autologous platelet-rich plasma for treating chronic wounds. Cochrane Database Syst Rev. 2012;10:CD006899.

Sugimori E, Shintani S, Ishikawa K, et al. Effects of apatite foam combined with platelet-rich plasma on regeneration of bone defects. Dent Mater J. 2006;25:591–6.

Iacopetti I, Perazzi A, Ferrari V, et al. Application of platelet-rich gel to enhance wound healing in the horse: a case report. J Equine Vet Sci. 2012;3:123–8.

Hokugo A, Ozeki M, Kawakami O, et al. Augmented bone regeneration activity of platelet-rich plasma by biodegradable gelatin hydrogel. Tissue Eng. 2005;11:1224–33.

Miyoshi M, Kawazoe T, Igawa HH, Tabata Y, Ikada Y, et al. Effects of bFGF incorporated into a gelatin sheet on wound healing. J Biomater Sci Polym Ed. 2005;16:893–907.