Gastrointestinal symptoms in primary care: Prevalence and association with depression and anxiety

Thompson, 2000, Irritable bowel syndrome in general practice: prevalence, characteristics, and referral, Gut, 46, 78, 10.1136/gut.46.1.78 Schappert, 1992, National Ambulatory Medical Care Survey: 1989 summary, Vital Health Stat, 13, 1 Spitzer, 1994, Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 study, JAMA, 272, 1749, 10.1001/jama.272.22.1749 Leon, 1995, Prevalence of mental disorders in primary care. Implications for screening, Arch Fam Med, 4, 857, 10.1001/archfami.4.10.857 Ormel, 1994, Common mental disorders and disability across cultures. Results from the WHO Collaborative Study on Psychological Problems in General Health Care, JAMA, 272, 1741, 10.1001/jama.272.22.1741 Olfson, 1997, Mental disorders and disability among patients in a primary care group practice, Am J Psychiatry, 154, 1734, 10.1176/ajp.154.12.1734 Ansseau, 2004, High prevalence of mental disorders in primary care, J Affect Disord, 78, 49, 10.1016/S0165-0327(02)00219-7 Kroenke, 2007, Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection, Ann Intern Med, 146, 317, 10.7326/0003-4819-146-5-200703060-00004 Löwe B, Spitzer RL, Williams JB, Mussell M, Schellberg D, Kroenke K. depression, anxiety, and somatization in primary care: syndrome overlap and functional impairment. Gen Hosp Psychiatry; in press. O'Malley, 1998, The value of screening for psychiatric disorders prior to upper endoscopy, J Psychosom Res, 44, 279, 10.1016/S0022-3999(97)00250-X Walker, 1992, Comorbidity of gastrointestinal complaints, depression, and anxiety in the Epidemiologic Catchment Area (ECA) Study, Am J Med, 92, 26S, 10.1016/0002-9343(92)90133-V North, 1996, Gastrointestinal symptoms and psychiatric disorders in the general population. Findings from NIMH Epidemiologic Catchment Area Project, Dig Dis Sci, 41, 633, 10.1007/BF02213117 Lydiard, 1994, Panic disorder and gastrointestinal symptoms: findings from the NIMH Epidemiologic Catchment Area project, Am J Psychiatry, 151, 64, 10.1176/ajp.151.1.64 Sareen, 2006, Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions, Arch Intern Med, 166, 2109, 10.1001/archinte.166.19.2109 Löwe, 2003, Predictors of psychiatric comorbidity in medical outpatients, Psychosom Med, 65, 764, 10.1097/01.PSY.0000079379.39918.17 Kroenke, 1997, Depressive and anxiety disorders in patients presenting with physical complaints: clinical predictors and outcome, Am J Med, 103, 339, 10.1016/S0002-9343(97)00241-6 Jackson, 2001, Clinical predictors of mental disorders among medical outpatients, Arch Intern Med, 161, 875, 10.1001/archinte.161.6.875 Kroenke, 1994, Physical symptoms in primary care. Predictors of psychiatric disorders and functional impairment, Arch Fam Med, 3, 774, 10.1001/archfami.3.9.774 Jackson, 1998, Clinical predictors of mental disorders among medical outpatients. Validation of the “S4” model, Psychosomatics, 39, 431, 10.1016/S0033-3182(98)71302-7 Simon, 1999, An international study of the relation between somatic symptoms and depression, N Engl J Med, 341, 1329, 10.1056/NEJM199910283411801 Löwe, 2003, Detecting panic disorder in medical and psychosomatic outpatients: comparative validation of the Hospital Anxiety and Depression Scale, the Patient Health Questionnaire, a screening question, and physicians' diagnosis, J Psychosom Res, 55, 515, 10.1016/S0022-3999(03)00072-2 Löwe, 2004, Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians' diagnoses, J Affect Disord, 78, 131, 10.1016/S0165-0327(02)00237-9 Spitzer, 2006, A brief measure for assessing generalized anxiety disorder: the GAD-7, Arch Intern Med, 166, 1092, 10.1001/archinte.166.10.1092 Stewart, 1988, The MOS short-form general health survey. Reliability and validity in a patient population, Med Care, 26, 724, 10.1097/00005650-198807000-00007 Kroenke, 2002, The PHQ-15: validity of a new measure for evaluating the severity of somatic symptoms, Psychosom Med, 64, 258, 10.1097/00006842-200203000-00008 Kroenke, 2002, The PHQ-9: a new depression diagnostic and severity measure, Psychiat Ann, 9, 1 Spitzer, 1999, Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study, JAMA, 282, 1737, 10.1001/jama.282.18.1737 Kroenke, 2001, The PHQ-9. Validity of a brief depression severity measure, J Gen Intern Med, 16, 606, 10.1046/j.1525-1497.2001.016009606.x Löwe, 2004, Diagnosing ICD-10 depressive episodes: superior criterion validity of the Patient Health Questionnaire, Psychother Psychosom, 73, 386, 10.1159/000080393 American Psychiatric Association, 2000 First, 1995 Wells, 1988, Agreement between face-to-face and telephone-administered versions of the depression section of the NIMH Diagnostic Interview Schedule, J Psychiatr Res, 22, 207, 10.1016/0022-3956(88)90006-4 Simon, 1993, Telephone assessment of depression severity, J Psychiatr Res, 27, 247, 10.1016/0022-3956(93)90035-Z Aneshensel, 1982, Measuring depression in the community: a comparison of telephone and personal interviews, Public Opin Q, 46, 110, 10.1086/268703 Connor, 2001, Mini-SPIN: a brief screening assessment for generalized social anxiety disorder, Depress Anxiety, 14, 137, 10.1002/da.1055 Rief, 2004, Base rates for panic and depression according to the Brief Patient Health Questionnaire: a population-based study, J Affect Disord, 82, 271, 10.1016/j.jad.2003.11.006 Löwe, 2004, Psychiatric comorbidity and work disability in patients with inflammatory rheumatic diseases, Psychosom Med, 66, 395, 10.1097/01.psy.0000126203.89941.a3 Löwe, 2004, Anxiety and depression in patients with pulmonary hypertension, Psychosom Med, 66, 831, 10.1097/01.psy.0000145593.37594.39 Kessler, 2003, The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R), JAMA, 289, 3095, 10.1001/jama.289.23.3095 Cohen, 1988 Kisely, 2006, An international study comparing the effect of medically explained and unexplained somatic symptoms on psychosocial outcome, J Psychosom Res, 60, 125, 10.1016/j.jpsychores.2005.06.064 Pajala, 2005, Mental distress in patients with functional or organic dyspepsia: a comparative study with a sample of the general population, Aliment Pharmacol Ther, 21, 277, 10.1111/j.1365-2036.2005.02296.x Pajala, 2006, A prospective 1-year follow-up study in patients with functional or organic dyspepsia: changes in gastrointestinal symptoms, mental distress and fear of serious illness, Aliment Pharmacol Ther, 24, 1241, 10.1111/j.1365-2036.2006.03108.x Henningsen, 2003, Medically unexplained physical symptoms, anxiety, and depression: a meta-analytic review, Psychosom Med, 65, 528, 10.1097/01.PSY.0000075977.90337.E7 Henningsen, 2007, Management of functional somatic syndromes, Lancet, 369, 946, 10.1016/S0140-6736(07)60159-7 Roy-Byrne, 1999, Panic disorder in the primary care setting: comorbidity, disability, service utilization, and treatment, J Clin Psychiatry, 60, 492, 10.4088/JCP.v60n0713 Roy-Byrne, 2004, Primary care perspectives on generalized anxiety disorder, J Clin Psychiatry, 65, 20 Hing, 2006 Jackson, 2006, Antidepressants and cognitive-behavioral therapy for symptom syndromes, CNS Spectr, 11, 212, 10.1017/S1092852900014383 Kroenke, 2000, Cognitive–behavioral therapy for somatization and symptom syndromes: a critical review of controlled clinical trials, Psychother Psychosom, 69, 205, 10.1159/000012395 Barlow, 2004, Toward a unified treatment for emotional disorders, Behav Ther, 35, 205, 10.1016/S0005-7894(04)80036-4 Whooley, 2000, Managing depression in medical outpatients, N Engl J Med, 343, 1942, 10.1056/NEJM200012283432607 Greco, 2004, The outcome of physical symptoms with treatment of depression, J Gen Intern Med, 19, 813, 10.1111/j.1525-1497.2004.30531.x Callahan, 2005, Treatment of depression improves physical functioning in older adults, J Am Geriatr Soc, 53, 367, 10.1111/j.1532-5415.2005.53151.x Lin, 2003, Effect of improving depression care on pain and functional outcomes among older adults with arthritis: a randomized controlled trial, JAMA, 290, 2428, 10.1001/jama.290.18.2428 Kroenke, 2003, The Patient Health Questionnaire-2: validity of a two-item depression screener, Med Care, 41, 1284, 10.1097/01.MLR.0000093487.78664.3C Löwe, 2005, Detecting and monitoring depression with a 2-item questionnaire (PHQ-2), J Psychosom Res, 58, 163, 10.1016/j.jpsychores.2004.09.006