Gastric acid secretion and intragastric acidity: measurement in health and disease

Armstrong, 1989, Twenty-four hour intragastric pH-metry studies: easy to do but difficult to analyse, European Journal of Gastroenterology and Hepatology, 1, 167 Baak, 1990, Effect of intravenous omeprazole on intragastric pH during intravenous infusion of amino acids, Digestive Diseases and Sciences, 5, 596, 10.1007/BF01540407 Baron, 1963, An assessment of the augmented histamine test in the diagnosis of peptic ulcer, Gut, 4, 243, 10.1136/gut.4.3.243 Baron, 1969, Lean body mass, gastric acid, and peptic ulcer, Gut, 10, 637, 10.1136/gut.10.8.637 Baron, 1978, History, methodology and interpretation Barthel, 1988, Gastritis and Campylobacter pylori in healthy, asymptomatic volunteers, Archives of Internal Medicine, 148, 1149, 10.1001/archinte.1988.00380050153022 Binder, 1978, Effect of cimetidine on intrinsic factor and pepsin secretion in man, Gastroenterology, 74, 371, 10.1016/0016-5085(78)90764-3 Blair, 1987, Variable contribution of gastrin to gastric acid secretion after a meal in humans, Gastroenterology, 92, 944, 10.1016/0016-5085(87)90968-1 Blair, 1987, Detailed comparison of basal and food-stimulated gastric acid secretion in normal subjects and patients with duodenal ulcer, Journal of Clinical Investigation, 79, 582, 10.1172/JCI112850 Blair, 1989, Effect of parietal cell vagotomy on acid secretory responsiveness to circulating gastrin in humans, Gastroenterology, 90, 1001, 10.1016/0016-5085(86)90879-6 Bodemar, 1978, Food-stimulated acid secretion measured by intragastric titration with bicarbonate in patients with duodenal and gastric ulcer disease and in controls, Scandinavian Journal of Gastroenterology, 13, 911, 10.3109/00365527809181368 Brooks, 1965, Insulin hypoglycaemia and gastric secretion, American Journal of Gastroenterology, 10, 737 Burget, 1990, Is there an optimal degree of acid suppression for healing of duodenal ulcers?, 99, 345 Chiverton, 1989, Does misoprostol given as a single large dose improve its antisecretory effect?, Alimentary Pharmacology and Therapeutics, 3, 403, 10.1111/j.1365-2036.1989.tb00228.x Chiverton, 1992, Omeprazole (20 mg) daily given in the morning or evening: a comparison of effects on gastric acidity, and plasma gastrin and omeprazole concentration, Alimentary Pharmacology and Therapeutics, 6, 103, 10.1111/j.1365-2036.1992.tb00550.x Collen, 1989, Refractory duodenal ulcers (non-healing duodenal ulcers with standard doses of anti-secretory medication), Digestive Diseases and Sciences, 34, 233, 10.1007/BF01536057 Collen, 1990, Gastric acid hypersecretion in refractory gastrooesophageal reflux, Gastroenterology, 98, 654, 10.1016/0016-5085(90)90285-9 Collen, 1992, Basal acid output and gastric acid hypersecretion in gastro-oesophageal reflux disease: correlation with ranitidine therapy, Gastroenterology, 102, A52, 10.1016/0016-5085(92)90366-7 Cox, 1952, Stomach size and its relation to chronic peptic ulcer, Archives of Pathology, 54, 407 Crean, 1977, The effects of 6 weeks' administration of cimetidine on gastric acid secretion, 217 Dooley, 1988, The clinical significance of Campylobacter pylori, 108, 70 Ellard, 1990, Acute and chronic stress in duodenal ulcer disease, Gastroenterology, 99, 1628, 10.1016/0016-5085(90)90467-F Eriksen, 1989, Effects of sham feeding and a meal on plasma gastrin and duodenal pH in normal and duodenal ulcer patients, 209, 411 Feldman, 1991, Fasting gastric pH and its relationship to true hypochlorhydria in humans, Digestive Diseases and Sciences, 36, 866, 10.1007/BF01297133 Feldman, 1986, Total 24-hour gastric acid secretion in patients with duodenal ulcer, Gastroenterology, 90, 540, 10.1016/0016-5085(86)91106-6 Feldman, 1980, Experience with sham feeding as a test for vagotomy, Gastroenterology, 79, 792, 10.1016/0016-5085(80)90430-8 Feldman, 1983, Sex-related differences in gastrin release and parietal cell sensitivity to gastrin in healthy human beings, Journal of Clinical Investigation, 71, 715, 10.1172/JCI110818 Fimmel, 1985, Long-term ambulatory gastric pH monitoring: validation of a new method and effect of H2-antagonists, Gastroenterology, 88, 1842, 10.1016/0016-5085(85)90009-5 Fordtran, 1973, Gastric acid secretion rate and buffer content of the stomach after eating, Journal of Clinical Investigation, 52, 645, 10.1172/JCI107226 Fraser, 1992, Twenty-four hour hyperpepsinogenaemia in Helicobacterpylori-positive subjects is abolished by eradication of the infection, Alimentary Pharmacology and Therapeutics, 6, 389, 10.1111/j.1365-2036.1992.tb00060.x Fullarton, 1989, Rebound nocturnal hypersecretion after four weeks treatment with an H2-receptor antagonist, Gut, 30, 449, 10.1136/gut.30.4.449 Gillespie, 1977, Short-term and maintenance cimetidine treatment in severe duodenal ulceration, 240 Goldschmiedt, 1991, Effect of age on gastric acid secretion and serum gastrin concentrations in healthy men and women, Gastroenterology, 101, 977, 10.1016/0016-5085(91)90724-Y Graham, 1989, Campylobacter pylori and peptic ulcer disease, Gastroenterology, 96, 615, 10.1016/S0016-5085(89)80057-5 Graham, 1988, Iatrogenic Campylobacter pylori infection is a cause of epidemic achlorhydria, American Journal of Gastroenterology, 83, 974 Graham, 1990, Ablation of exaggerated meal-stimulated gastrin release in duodenal ulcer patients after clearance of Helicobacter (Campylobacter) pylori infection, American Journal of Gastroenterology, 85, 394 Griffith, 1991, Development of sustained achlorhydria in a patient with Zollinger-Ellison syndrome treated with omeprazole, Gastroenterology, 101, 242, 10.1016/0016-5085(91)90484-3 Gross, 1978, Effect of fat on meal stimulated duodenal acid load, duodenal pepsin load and serum gastrin in duodenal ulcer and normal subjects, Gastroenterology, 75, 357, 10.1016/0016-5085(78)90832-6 Hannan, 1992, Effects of pantoprazole on 24-h intragastric acidity and plasma gastrin, Alimentary Pharmacology and Therapeutics, 6, 373, 10.1111/j.1365-2036.1992.tb00058.x Hassan, 1970, Positioning of subject and of nasogastric tube during a gastric secretion study, British Medical Journal, 1, 458, 10.1136/bmj.1.5694.458 Hetzel, 1978, Cimetidine treatment of duodenal ulcer: short-term clinical trial and maintenance study, Gastroenterology, 74, 389, 10.1016/0016-5085(78)90767-9 Hirschowitz, 1984, Apparent and intrinsic sensitivity to pentagastrin of acid and pepsin secretion in peptic ulcer, Gastroenterology, 86, 843 Hirschowitz, 1991, A critical analysis, with appropriate controls, of gastric acid and pepsin secretion in clinical esophagitis, Gastroenterology, 101, 1149, 10.1016/0016-5085(91)90062-P Hobsley, 1969, Use of an inert marker (phenol red) to improve accuracy in gastric secretion studies, Gut, 10, 787, 10.1136/gut.10.10.787 Holtmann, 1990, Differential effects of acute mental stress on interdigestive secretion of gastric acid, pancreatic enzymes, and gastroduodenal motility, Digestive Diseases and Sciences, 35, 998, 10.1007/BF01537249 Hood, 1976, Predictive value of perioperative gastric acid tests, Gut, 17, 998, 10.1136/gut.17.12.998 Hopert, 1989, Reduction of 24-hour gastric acidity by different dietary regimens: a randomized controlled study in healthy volunteers, Journal of Parenteral and Enteral Nutrition, 13, 292, 10.1177/0148607189013003292 Howden, 1989, Twenty-four hour intragastric acidity in duodenal ulcer patients during dosing with placebo, and 150 mg ranitidine twice or four times daily, Alimentary Pharmacology and Therapeutics, 3, 253, 10.1111/j.1365-2036.1989.tb00211.x Humbert, 1992, Oral magnesium hydrogen breath test using end-expiratory sampling: a simple method to assess achiorhydria, Gastroenterology, 102, A86 Inman, 1990, Effect of truncal vagotomy on parietal cell mass and antral gastric cell mass in dogs, Gastroenterology, 99, 1581, 10.1016/0016-5085(90)90461-9 Isenberg, 1968, Pentagastrin vs betazole as stimulant of gastric secretion, 206, 2897 Isenberg, 1975, Increased sensitivity to stimulation of acid secretion by pentagastrin in duodenal ulcer, Journal of Clinical Investigation, 55, 330, 10.1172/JCI107936 Johnson, 1967, Use of pentagastrin in a test of gastric acid secretion, Lancet, ii, 585, 10.1016/S0140-6736(67)90739-8 Johnston, 1990, Duodenal ulcer healing and acid secretory responses to modified sham feeding and pentagastrin stimulation, Alimentary Pharmacology and Therapeutics, 4, 403, 10.1111/j.1365-2036.1990.tb00486.x Karnes, 1990, Prolonged inhibition of acid secretion causes hypergastrinaemia without altering pH inhibition of gastrin release in humans, Alimentary Pharmacology and Therapeutics, 4, 443, 10.1111/j.1365-2036.1990.tb00491.x Katelaris, 1992, The effect of age, gastric acid secretion and serum gastrin concentrations in healthy males, Gastroenterology, 102, A560 Kaufmann, 1990, Cigarette smoking, gastric acidity and peptic ulceration, 35, 1482 Kay, 1953, Effect of large doses of histamine on gastric secretion of HC1, British Medical Journal, 2, 77, 10.1136/bmj.2.4827.77 Kekki, 1983, Age behaviour of gastrin acid secretion in males and females with a normal antral and body mucosa, Scandinavian Journal of Gastroenterology, 18, 1009, 10.3109/00365528309181834 Kolbel, 1988, Pancreatic and gastric responses to gastric versus jejunal beer in humans, Pancreas, 3, 89, 10.1097/00006676-198802000-00015 Kronberg, 1980, Acid responses to sham feeding as a test for completeness of vagotomy, Scandinavian Journal of Gastroenterology, 15, 119, 10.3109/00365528009181442 Kummer, 1992, Changes in nocturnal and peak acid outputs after duodenal ulcer healing with sucralfate or ranitidine, Gut, 33, 175, 10.1136/gut.33.2.175 Lanzon-Miller, 1992, The effect of fasting on 24-hour intragastric acidity and plasma gastrin concentration, American Journal of Gastroenterology, 86, 165 Lanzon-Miller, 1987, Twenty-four hour intragastric acidity and plasma gastrin concentration in healthy subjects and patients with duodenal or gastric ulcer or pernicious anaemia, Alimentary Pharmacology and Therapeutics, 1, 225, 10.1111/j.1365-2036.1987.tb00622.x Lanzon-Miller, 1987, Twenty-four hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or omeprazole, Alimentary Pharmacology and Therapeutics, 1, 239, 10.1111/j.1365-2036.1987.tb00623.x Lanzon-Miller, 1988, Enprostil inhibits post-prandial gastrin release: a dose-response study, Alimentary Pharmacology and Therapeutics, 2, 317, 10.1111/j.1365-2036.1988.tb00703.x Lanzon-Miller, 1991, The timing of the evening meal affects the pattern of 24-hour intragastric acidity, Alimentary Pharmacology and Therapeutics, 4, 547, 10.1111/j.1365-2036.1990.tb00501.x Lennard-Jones, 1965, Effect of different foods on the acidity of the gastric contents in patients with duodenal ulcer. Part I: a comparison between two ‘therapeutic’ diets and freely-chosen meals, Gut, 6, 113, 10.1136/gut.6.2.113 Levi, 1989, Antral Helicobacter pylori, hypergastrinaemia, and duodenal ulcers: effect of eradicating the organism, British Medical Journal, 299, 1504, 10.1136/bmj.299.6714.1504 Levi, 1989, Campylobacter pylori and duodenal ulcers: the gastrin link, Lancet, i, 1167, 10.1016/S0140-6736(89)92752-9 Lind, 1990, 24-hour intragastric acidity and plasma gastrin after omeprazole treatment and after proximal gastric vagotomy in duodenal ulcer patients, Gastroenterology, 99, 1593, 10.1016/0016-5085(90)90462-A Londong, 1983, Dose-response study of omeprazole on meal-stimulated gastric acid secretion and gastrin release, Gastroenterology, 85, 1373, 10.1016/S0016-5085(83)80020-1 Londong, 1990, Standardization of electrode positioning and composition of meals for long-term intragastric pH metry in man, Digestive Diseases, 8, 46, 10.1159/000171279 Londong, 1990, Long-term intragastric pH measurement in man, Digestive Diseases, 8, 1, 10.1159/000171272 McArthur, 1982, Relative stimulatory effects of commonly ingested beverages on gastric acid secretion in humans, Gastroenterology, 83, 199, 10.1016/0016-5085(82)90175-5 McColl, 1990, Serum gastrin and gastric acid status one and seven months after eradication of Helicobacter pylori in duodenal ulcer patients, Gut, 31, A601 McGuigan, 1980, Secretin injection test in the diagnosis of the gastrinoma, Gastroenterology, 79, 1324, 10.1016/0016-5085(80)90933-6 Mahachai, 1985, Antisecretory and serum gastrin lowering effect of enprostil in patients with duodenal ulcer disease, Gastroenterology, 89, 555, 10.1016/0016-5085(85)90451-2 Malegelada, 1977, Gastric acid secretion and emptying after ordinary meals in duodenal ulcer, Gastroenterology, 73, 989, 10.1016/S0016-5085(19)31911-0 Masoero, 1991, Prolonged gastric pH monitoring in responder and nonresponder duodenal ulcer patients: response to placebo and to H2-blockade administration, Journal of Clinical Gastroenterology, 13, 291, 10.1097/00004836-199106000-00008 Mela, 1990, Continuous acidity monitoring in the study of gastric antisecretory drugs: pH or antilog transformation of pH, mean, or median, American Journal of Gastroenterology, 85, 1105 Merki, 1988, Day-to-day variations of 24-hour intragastric acidity, Gastroenterology, 94, 887, 10.1016/0016-5085(88)90543-4 Merki, 1988, Pattern of 24-hour intragastric acidity in active duodenal ulcer disease and in healthy controls, Gut, 29, 1583, 10.1136/gut.29.11.1583 Merki, 1990, Effect of food on H2-receptor blockade in normal subjects and duodenal ulcer patients, Gut, 31, 148, 10.1136/gut.31.2.148 Moore, 1970, Circadian rhythm of gastric acid secretion in man, Nature, 226, 1261, 10.1038/2261261a0 Moore, 1990, Circadian rhythm of gastric acid secretion in men with active duodenal ulcer, Digestive Diseases and Sciences, 31, 1185, 10.1007/BF01296516 Morris, 1987, Ingestion of Campylobacter pyloridis causes gastritis and raised fasting gastric pH, American Journal of Gastroenterology, 82, 192 Mulholland, 1988, Physiology and pathophysiology of gastrin: a review, Surgery, 103, 135 Murphy, 1991, Modulation of gastric pH by continuous gastric and jejunal infusion of cimetidine, Digestive Diseases and Sciences, 36, 137, 10.1007/BF01300746 Nagashima, 1981, Mechanisms of action of sucralfate, Journal of Clinical Gastroenterology, 3, 117 Nicol, 1991, Measurement of gastric secretion as a student teaching exercise, American Journal of Physiology, 261, S20 Nwokolo, 1990, Tolerance during 29 days of conventional dosing with cimetidine, nizatidine, famotidine or ranitidine, Alimentary Pharmacology and Therapeutics, 4S, 29 Nwokolo, 1990, Intravenous pentagastrin can induce the illusion of ‘tolerance’ to a single dose of an H2-blocker in man, Alimentary Pharmacology and Therapeutics, 4S, 75 Nwokolo, 1991, Rebound intragastric hyperacidity after abrupt withdrawal of histamine H2-receptor antagonist, Gut, 32, 1455, 10.1136/gut.32.12.1455 Nwokolo, 1992, Tolerance during 5 months of dosing with ranitidine 150 mg nocte—a placebo-controlled double-blind study, Gastroenterology, 101, 948, 10.1016/0016-5085(91)90720-6 Oderda, 1989, Amoxycillin plus tinidazole for Campylobacter pylori gastritis in children: assessment by serum IgG antibody, pepsinogen 1, and gastrin levels, Lancet, i, 690, 10.1016/S0140-6736(89)92206-X Orr, 1988, The timing of evening meal and ranitidine administration—effects on patterns of 24 hour intragastric acidity, Alimentary Pharmacology and Therapeutics, 2, 541, 10.1111/j.1365-2036.1988.tb00729.x Peterson, 1979, Reduction of 24-hour gastric acidity with combination drug therapy in patients with duodenal ulcer, Gastroenterology, 77, 1015, 10.1016/S0016-5085(79)80071-2 Petersen, 1986, Effect of intragastric infusions of ethanol and wine on serum gastrin concentration and gastric acid secretion, Gastroenterology, 91, 1390, 10.1016/0016-5085(86)90192-7 Petersen, 1987, The role of Campylobacter pyloridis in epidemic gastritis with hypochlorhydria, Gastroenterology, 92, 1575 Poulsen, 1986, Fasting and food stimulated serum gastrin concentration in 151 duodenal ulcer patients and 41 non-dyspeptic volunteers, 21, 881 Pounder, 1984, Histamine2-receptor antagonists and gastric acid secretion, Pharmacology and Therapeutics, 26, 221, 10.1016/0163-7258(84)90018-4 Pounder, 1990, Acid suppression, British Medical Journal, 301, 1329, 10.1136/bmj.301.6764.1329-b Pounder, 1990, Drug-induced changes of plasma gastrin concentration, Gastroenterology Clinics of North America, 19, 141, 10.1016/S0889-8553(21)00461-1 Pounder, 1975, Twenty-four hour control of intragastric acidity by cimetidine in duodenal ulcer patients, Lancet, ii, 1069, 10.1016/S0140-6736(75)90434-1 Pounder, 1976, Inhibition of food-stimulated gastric acid secretion by cimetidine, Gut, 17, 161, 10.1136/gut.17.3.161 Pounder, 1990, Royal Free Hospital Protocol for 24-hour intragastric acidity and plasma gastrin concentration, Digestive Diseases, 8, 10, 10.1159/000171287 Prewett, 1991, 24-hour intra-gastric acidity and plasma gastrin concentration in female and male subjects, Clinical Science, 80, 616, 10.1042/cs0800619 Prewett, 1991, Eradication of Helicobacter pylori abolishes 24-hour hypergastrinaemia: a prospective study in healthy subjects, Alimentary Pharmacology and Therapeutics, 5, 283, 10.1111/j.1365-2036.1991.tb00029.x Prewett, 1991, The effect of GR122311X, a bismuth compound with H2-antagonist activity, on 24-hour intragastric acidity, Alimentary Pharmacology and Therapeutics, 5, 481, 10.1111/j.1365-2036.1991.tb00517.x Prewett, 1991, Nocturnal intragastric acidity and after a period of dosing with either ranitidine or omeprazole, Gastroenterology, 100, 873, 10.1016/0016-5085(91)90258-M Prichard, 1986, The effectiveness of ranitidine in reducing gastric acid-secretion decreases with continued therapy, British Journal of Clinical Pharmacology, 22, 663, 10.1111/j.1365-2125.1986.tb02955.x Primrose, 1988, Highly selective vagotomy and duodenal ulcers that fail to respond to H2-receptor antagonists, British Medical Journal, 296, 1031, 10.1136/bmj.296.6628.1031 Rademaker, 1991, Helicobacter pylori and gastric acid secretion, Scandinavian Journal of Gastroenterology, 26, 71, 10.3109/00365529109098227 Ramsey, 1976, Epidemic gastritis with hypochlorhydria, Gastroenterology, 76, 1449, 10.1016/0016-5085(79)90415-3 Rogers, 1990, The effects of 15 days of dosing with placebo, sufotidine 600 mg nocte or sufotidine 600 mg twice daily upon 24-hour intragastric acidity and 24-hour plasma gastrin, Alimentary Pharmacology and Therapeutics, 4, 65 Rohmel, 1990, Analysis and statistical evaluation of continuous pH recordings, Digestive Diseases, 8, 87, 10.1159/000171284 Sanders, 1992, The effects of lansoprazole, a new H+K+ATPase inhibitor, on gastric pH and serum gastrin, Alimentary Pharmacology and Therapeutics, 6, 359, 10.1111/j.1365-2036.1992.tb00057.x Sanders, 1977, Long-term effects and after-effects of treatment of duodenal ulcer with metiamide, Lancet, i, 765, 10.1016/S0140-6736(77)92954-3 Savarino, 1987, 24-hour comparison between pH values of continuous intraluminal recording and simultaneous gastric aspiration, Scandinavian Journal of Gastroenterology, 22, 135, 10.3109/00365528708991870 Schubert, 1990, Control of gastric acid secretion, Gastroenterology Clinics of North America, 19, 1, 10.1016/S0889-8553(21)00454-4 Sharma, 1984, Optimal dose of oral omeprazole for maximal 24-hour decrease of intragastric acidity, Gut, 25, 957, 10.1136/gut.25.9.957 Sharma, 1987, Acid secretory capacity and plasma gastrin concentration after administration of omeprazole to normal subjects, Alimentary Pharmacology and Therapeutics, 1, 67, 10.1111/j.1365-2036.1987.tb00608.x Sidebotham, 1990, Some effects of tripotassium dicitrato bismuthate on gastric secretion and the mucus barrier, Alimentary Pharmacology and Therapeutics, 4, 535, 10.1111/j.1365-2036.1990.tb00500.x Smith, 1990, Inappropriate hypergastrinaemia in asymptomatic healthy subjects infected with Helicobacter pylori, Gut, 31, 522, 10.1136/gut.31.5.522 Smith, 1990, Tolerance during 8 days of high-dose H2-blockade: placebo-controlled studies of 24-h acidity and gastrin, Alimentary Pharmacology and Therapeutics, 4S, 47 Sobala, 1988, Acute Helicobacter pylori infection: clinical features, local and systemic response, gastric mucosal histology, and gastric juice ascorbic acid concentration, Gut, 32, 1415, 10.1136/gut.32.11.1415 Soll, 1987, Anti-secretory drugs—cellular mechanisms of action, Alimentary Pharmacology and Therapeutics, 1, 77, 10.1111/j.1365-2036.1987.tb00609.x Van-Loon, 1990, Low gastric acid as a risk factor for cholera transmission: application of a new non-invasive gastric acid field test, Journal of Clinical Epidemiology, 43, 1361, 10.1016/0895-4356(90)90103-V Wagner, 1991, Circadian pattern of intragastric acidity in duodenal ulcer patients: a study of variations in relation to ulcer activity, Gut, 32, 1104, 10.1136/gut.32.10.1104 Wallmark, 1989, Omeprazole: mode of action and effect on acid secretion in animals, Scandinavian Journal of Gastroenterology, 24, 12, 10.3109/00365528909091237 Walsh, 1975, pH dependence of acid secretion and gastrin release in normal and ulcer subjects, Journal of Clinical Investigation, 55, 462, 10.1172/JCI107952 Walt, 1983, Profound decrease of 24-hour intragastric acidity by daily oral omeprazole, British Medical Journal, 287, 12, 10.1136/bmj.287.6384.12 Watkinson, 1951, A study of the changes of pH of gastric contents in peptic ulcer using the twenty-four hour test meal, Gastroenterology, 18, 377, 10.1016/S0016-5085(51)80004-0 Wilder-Smith, 1990, Loss of acid suppression during dosing with H2-receptor antagonists, Alimentary Pharmacology and Therapeutics, 4S, 15 Wilder-Smith, 1990, Tolerance to oral H2-receptor antagonists, Digestive Diseases and Sciences, 8, 976, 10.1007/BF01537246