Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults

Environmental Research - Tập 212 - Trang 113360 - 2022
Katelyn M. Holliday1,2, Rahul Gondalia2, Antoine Baldassari2, Anne E. Justice3, James D. Stewart2, Duanping Liao4, Jeff D. Yanosky4, Kristina M. Jordahl5, Parveen Bhatti6, Themistocles L. Assimes7, James S. Pankow8, Weihua Guan9, Myriam Fornage10,11, Jan Bressler11, Kari E. North2, Karen N. Conneely12, Yun Li13,14,15, Lifang Hou16,17, Pantel S. Vokonas18, Cavin K. Ward-Caviness19
1Department of Family Medicine and Community Health, School of Medicine, Duke University, Durham, NC, USA
2Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA
3Geisinger Health System, Danville, PA, USA
4Division of Epidemiology, Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA
5Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA
6Cancer Control Research, BC Cancer, Vancouver BC, Canada
7Department of Medicine,, Stanford University School of Medicine, Stanford, CA USA
8Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
9Division of Biostatistics, University of Minnesota, Minneapolis MN, USA
10Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA
11Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA
12Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA
13Department of Genetics, University of North Carolina, Chapel Hill, NC, USA
14Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA
15Department of Computer Science, University of North Carolina, Chapel Hill, NC, USA
16Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University Chicago, Evanston, IL, USA
17Center for Population Epigenetics, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University Chicago, Evanston, IL, USA
18VA Normative Aging Study, VA Boston Healthcare System, Schools of Medicine and Public Health, Boston University, Boston, MA, USA
19Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, 104 Mason Farm Rd, Chapel Hill, NC, 27514, USA

Tài liệu tham khảo

Andrews, 2016, Gap hunting” to characterize clustered probe signals in Illumina methylation array data, Epigenet. Chromatin, 9 Baccarelli, 2009, Epigenetics and environmental chemicals, Curr. Opin. Pediatr., 21, 243, 10.1097/MOP.0b013e32832925cc Baccarelli, 2012, Environmental exposures, epigenetics and cardiovascular disease, Curr. Opin. Clin. Nutr. Metab. Care, 15, 323, 10.1097/MCO.0b013e328354bf5c Balti, 2014, Air pollution and risk of type 2 diabetes mellitus: a systematic review and meta-analysis, Diabetes Res. Clin. Pract., 106, 161, 10.1016/j.diabres.2014.08.010 Bell, 1996, The Veterans Administration longitudinal study of healthy aging, Gerontol., 6, 179, 10.1093/geront/6.4.179 Bellavia, 2013, DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments, J. Am. Heart Assoc., 2, 10.1161/JAHA.113.000212 Bernstein, 2010, The NIH Roadmap Epigenomics mapping consortium, Nat. Biotechnol., 28, 1045, 10.1038/nbt1010-1045 Bind, 2012, Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort, Epidemiology, 23, 332, 10.1097/EDE.0b013e31824523f0 Bind, 2014, Air pollution and gene-specific methylation in the Normative Aging Study: association, effect modification, and mediation analysis, Epigenetics, 9, 448, 10.4161/epi.27584 Chi, 2016, Long-term outdoor air pollution and DNA methylation in circulating monocytes: results from the Multi-Ethnic Study of Atherosclerosis (MESA), Environ. Health, 15, 119, 10.1186/s12940-016-0202-4 de F C Lichtenfels, 2018, Long-term air pollution exposure, genome-wide DNA methylation and lung function in the LifeLines cohort study, Environ. Health Perspect., 26, 10.1289/EHP2045 De Prins, 2013, Influence of ambient air pollution on global DNA methylation in healthy adults: a seasonal follow-up, Environ. Int., 59, 418, 10.1016/j.envint.2013.07.007 Demerath, 2015, Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci, Hum. Mol. Genet., 24, 4464, 10.1093/hmg/ddv161 Devlin, 1999, Genomic control for association studies, Biometrics, 55, 997, 10.1111/j.0006-341X.1999.00997.x Dhanoa, 2013, Update on the Kelch-like (KLHL) gene family, Hum. Genom., 7, 13, 10.1186/1479-7364-7-13 Diez Roux, 2001, Neighborhood of residence and incidence of coronary heart disease, N. Engl. J. Med., 345, 99, 10.1056/NEJM200107123450205 Eze, 2015, Association between ambient air pollution and diabetes mellitus in Europe and North America: systematic review and meta-analysis, Environ. Health Perspect., 123, 381, 10.1289/ehp.1307823 Fan, 2014, Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study, BMC Publ. Health, 14, 10.1186/1471-2458-14-1279 Franklin, 2015, Air pollution and cardiovascular disease, Curr. Probl. Cardiol., 40, 207, 10.1016/j.cpcardiol.2015.01.003 Fu, 2012, An environmental epigenetic study of ADRB2 5'-UTR methylation and childhood asthma severity, Clin. Exp. Allergy, 42, 1575, 10.1111/j.1365-2222.2012.04055.x Gondalia, 2019, Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation, Environ. Int., 132, 104723, 10.1016/j.envint.2019.03.071 Holle, 2005, KORA—a research platform for population based health research, Gesundheitswesen, 67, S19, 10.1055/s-2005-858235 Holliday, 2014, Estimating personal exposures from ambient air pollution measures using meta-analysis to assess measurement error, Epidemiology, 25, 35, 10.1097/EDE.0000000000000006 Hǒrejší, 2004, Transmembrane adaptor proteins: organizers of immunoreceptor signalling, Nat. Rev. Immunol., 4, 603, 10.1038/nri1414 Houseman, 2012, DNA methylation arrays as surrogate measures of cell mixture distribution, BMC Bioinf., 13 Howson, 2017, Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms, Nat. Genet., 49, 1113, 10.1038/ng.3874 Hur, 2003, LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation, J. Exp. Med., 198, 1463, 10.1084/jem.20030232 Johnson, 2007, Adjusting batch effects in microarray expression data using empirical Bayes methods, Biostatistics, 8, 118, 10.1093/biostatistics/kxj037 Jordahl, 2018, Genome-wide DNA methylation in prediagnostic blood and bladder cancer risk in the Women's health initiative, Cancer Epidemiol. Biomarkers Prev., 27, 689, 10.1158/1055-9965.EPI-17-0951 Kuhn, 2013, The UCSC genome browser and associated tools, Briefings Bioinf., 14, 144, 10.1093/bib/bbs038 Laity, 2001, Zinc finger proteins: new insights into structural and functional diversity, Curr. Opin. Struct. Biol., 11, 39, 10.1016/S0959-440X(00)00167-6 Lau, 2017, High-resolution genetic maps identify multiple type 2 diabetes loci at regulatory hotspots in African Americans and Europeans, Am. J. Hum. Genet., 100, 803, 10.1016/j.ajhg.2017.04.007 Lee, 2019, Genome-wide DNA methylation and longterm ambient air pollution exposure in Korean adults, Clin. Epigenet., 11 Lepeule, 2014, Epigenetic influences on associations between air pollutants and lung function in elderly men: the normative aging study, Environ. Health Perspect., 122, 566, 10.1289/ehp.1206458 Liao, 2006, GIS approaches for the estimation of residential-level ambient PM concentrations, Environ. Health Perspect., 114, 1374, 10.1289/ehp.9169 Madrigano, 2011, Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men, Environ. Health Perspect., 119, 977, 10.1289/ehp.1002773 Mukhopadhyay, 2007, Proteasome-independent functions of ubiquitin in endocytosis and signaling, Science, 315, 201, 10.1126/science.1127085 Panni, 2016, Genome-wide analysis of DNA methylation and fine particulate matter air pollution in three study populations: KORA F3, KORA F4, and the normative aging study, Environ. Health Perspect., 124, 983, 10.1289/ehp.1509966 Parikh, 2007, TXNIP regulates peripheral glucose metabolism in humans, PLoS Med., 4, e158, 10.1371/journal.pmed.0040158 Park, 2014, Ambient air pollution and type 2 diabetes: a systematic review of epidemiologic research, Curr. Environ. Health Rep., 1, 275, 10.1007/s40572-014-0017-9 Plusquin, 2017, DNA methylation and exposure to ambient air pollution in two prospective cohorts, Environ. Int., 108, 127, 10.1016/j.envint.2017.08.006 Price, 2006, Principal components analysis corrects for stratification in genome-wide association studies, Nat. Genet., 38, 904, 10.1038/ng1847 Rosenbloom, 2012, ENCODE whole-genome data in the UCSC Genome Browser: update 2012, Nucleic Acids Res., 40, D912, 10.1093/nar/gkr1012 Sayols-Baixeras, 2019, Association between long-term air pollution exposure and DNA methylation: the REGICOR study, Environ. Res., 176, 10.1016/j.envres.2019.108550 Schlaepfer, 2020, CPT1A-mediated fat oxidation, mechanisms, and therapeutic potential, Endocrinology, 161, 1, 10.1210/endocr/bqz046 Sofer, 2013, Exposure to airborne particulate matter is associated with methylation pattern in the asthma pathway, Epigenomics, 5, 147, 10.2217/epi.13.16 Tarantini, 2009, Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation, Environ. Health Perspect., 117, 217, 10.1289/ehp.11898 1989, The atherosclerosis risk in communities (ARIC) study: design and objectives, Am. J. Epidemiol., 129, 687, 10.1093/oxfordjournals.aje.a115184 1998, Design of the Women's Health Initiative clinical trial and observational study, Contr. Clin. Trials, 19, 61, 10.1016/S0197-2456(97)00078-0 van Buuren, 2011, Mice: multivariate imputation by chained equations in R, J. Stat. Software, 45, 1 van der Harst, 2018, The identification of 64 novel genetic loci provides an expanded view on the genetic architecture of coronary artery disease, Circ. Res., 122, 433, 10.1161/CIRCRESAHA.117.312086 Ward-Caviness, 2016, Long-term exposure to air pollution is associated with biological aging, Oncotarget, 7, 74510, 10.18632/oncotarget.12903 Wichmann, 2005, KORA-gen—resource for population genetics, controls and a broad spectrum of disease phenotypes, Gesundheitswesen, 67, 26, 10.1055/s-2005-858226 Wu, 2014, A systematic assessment of normalization approaches for the Infinium 450K methylation platform, Epigenetics, 9, 318, 10.4161/epi.27119