Gain-of-function miRNA signature by mutant p53 associates with poor cancer outcome
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bond, 2015, Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer, Cancer research, 75, 698, 10.1158/0008-5472.CAN-14-2637
Xu, 2013, The gain of function of p53 cancer mutant in promoting mammary tumorigenesis, Oncogene, 32, 2900, 10.1038/onc.2012.299
Blagosklonny, 2002, P53: an ubiquitous target of anticancer drugs, International journal of cancer, 98, 161, 10.1002/ijc.10158
Kim, 2006, AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability, Cancer research, 66, 6913, 10.1158/0008-5472.CAN-05-3740
Fang, 2013, RhoGAPs attenuate cell proliferation by direct interaction with p53 tetramerization domain, Cell reports, 3, 1526, 10.1016/j.celrep.2013.04.017
Vousden, 2006, TIGAR, a p53-inducible regulator of glycolysis and apoptosis, Cell, 126, 107, 10.1016/j.cell.2006.05.036
He, 2013, Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury, Eur Heart J, 34, 1834, 10.1093/eurheartj/ehs011
Blagosklonny, 2000, p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect, The FASEB Journal, 14, 1901, 10.1096/fj.99-1078rev
Lozano, 2004, Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome, Cell, 119, 861, 10.1016/j.cell.2004.11.006
Blagosklonny, 2005, Complementation of two mutant p53: Implications for loss of heterozygosity in cancer, FEBS letters, 579, 2231, 10.1016/j.febslet.2005.03.012
Fang, 2014, Heterogeneity of Li-Fraumeni syndrome links to unequal gain-of-function effects of p53 mutations, Scientific reports, 4, 4223, 10.1038/srep04223
Prives, 2012, Mutant p53: one name, many proteins, Genes & development, 26, 1268, 10.1101/gad.190678.112
Daggett, 2011, Structural effects of the L145Q, V157F, and R282W cancer-associated mutations in the p53 DNA-binding core domain, Biochemistry, 50, 5345, 10.1021/bi200192j
Rousseau, 2011, Gain of function of mutant p53 by coaggregation with multiple tumor suppressors, Nature chemical biology, 7, 285, 10.1038/nchembio.546
Fang, 2014, Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity, Cell death & disease, 5, e1108, 10.1038/cddis.2014.75
Fang, 2013, Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study, PloS one, 8, e73683, 10.18632/oncotarget.3005
Liu, 2010, An in silico analysis of microRNAs: mining the miRNAome, Molecular bioSystems, 6, 1853, 10.1039/c003961f
Chen, 2015, Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma, Oncotarget, 6, 4537, 10.18632/oncotarget.3005
Xu, 2015, A radiosensitivity MiRNA signature validated by the TCGA database for head and neck squamous cell carcinomas, Oncotarget, 6, 34649, 10.18632/oncotarget.5299
Meller, 2014, TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma, Cancer cell, 26, 738, 10.1016/j.ccell.2014.09.015
Sumani, 2014, MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer, Cancer cell, 25, 469, 10.1016/j.ccr.2014.03.006
Fang, 2015, Roles of competing endogenous RNAs in gastric cancer, Briefings in functional genomics
Guo, 2014, Long noncoding RNA associated-competing endogenous RNAs in gastric cancer, Scientific reports, 4, 6088, 10.1038/srep06088
Xu, 2015, Gastric cancer and gene copy number variation: emerging cancer drivers for targeted therapy, Oncogene
Xu, 2015, Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers, Oncogene
Hermeking, 2012, MicroRNAs in the p53 network: micromanagement of tumour suppression, Nature Reviews Cancer, 12, 613, 10.1038/nrc3318
Fang, 2014, Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer, Cancer research, 74, 6890, 10.1158/0008-5472.CAN-14-0686
Gomes, 2015, Functional and molecular characterization of cancer stem-like cells in bladder cancer: a potential signature for muscle-invasive tumors, Oncotarget, 6, 36185, 10.18632/oncotarget.5517
Caudell, 2015, The radiosensitivity index predicts for overall survival in glioblastoma, Oncotarget, 6, 34414, 10.18632/oncotarget.5437
Xu, 2006, Rat toxicogenomic study reveals analytical consistency across microarray platforms, Nat Biotechnol, 24, 1162, 10.1038/nbt1238
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol. 2006; 24:1151–1161.
Bao, 2008, The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies, BMC Bioinformatics, 9, S10, 10.1186/1471-2105-9-S9-S10
Marincola, 2010, MicroRNA expression differentiates histology and predicts survival of lung cancer, Clinical Cancer Research, 16, 430, 10.1158/1078-0432.CCR-09-1736
Lee, 2003, Local-pooled-error test for identifying differentially expressed genes with a small number of replicated microarrays, Bioinformatics, 19, 1945, 10.1093/bioinformatics/btg264
Liu, 2010, A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancer, PloS one, 5, e13735, 10.1371/journal.pone.0013735
Remaley, 2011, MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins, Nature cell biology, 13, 423, 10.1038/ncb2210
Hermeking, 2015, p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses, Molecular & cellular proteomics, 14, 2609, 10.1074/mcp.M115.050237
Cancer Genome Atlas Research N, 2014, Comprehensive molecular characterization of gastric adenocarcinoma, Nature, 513, 202, 10.1038/nature13480
Fang, 2014, Long noncoding RNA profiles identify five distinct molecular subtypes of colorectal cancer with clinical relevance, Molecular oncology, 8, 1393, 10.1016/j.molonc.2014.05.010
Ragoussis, 2011, microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer, Cancer research, 71, 5635, 10.1158/0008-5472.CAN-11-0489
Hatzigeorgiou, 2015, DIANA-miRPath v3. 0: deciphering microRNA function with experimental support, Nucleic acids research, 43, W460, 10.1093/nar/gkv403
Camargo, 2013, The hippo tumor suppressor network: from organ size control to stem cells and cancer, Cancer research, 73, 6389, 10.1158/0008-5472.CAN-13-2392
Nagase, 2015, Hippo and TGF-beta interplay in the lung field. American journal of physiology Lung cellular and molecular physiology, Am J Physiol Lung Cell Mol Physiol, 309, L756, 10.1152/ajplung.00238.2015
Mullen, 2014, Hippo tips the TGF-beta scale in favor of pluripotency, Cell stem cell, 14, 6, 10.1016/j.stem.2013.12.009
Van Maerken, 2015, Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma, Scientific reports, 5, 9027, 10.1038/srep09027
Castellano, 2013, The p53 miRNA interactome and its potential role in the cancer clinic, Epigenomics, 5, 417, 10.2217/epi.13.41
Mizutani, 2012, Analysis of p53 and miRNA expression after irradiation of glioblastoma cell lines, Anticancer research, 32, 4709
Landi, 2013, More targets, more pathways and more clues for mutant p53, Oncogenesis, 2, e54, 10.1038/oncsis.2013.15
Pan, 2015, YAPing Hippo Forecasts a New Target for Lung Cancer Prevention and Treatment, Journal of clinical oncology, 33, 2311, 10.1200/JCO.2015.61.2093
Sudo, 2014, Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties, Cancer research, 74, 4170, 10.1158/0008-5472.CAN-13-3569
Kim, 2011, Comprehensive evaluation of matrix factorization methods for the analysis of DNA microarray gene expression data, BMC bioinformatics, 12, S8, 10.1186/1471-2105-12-S13-S8