GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

Chemistry & Biology - Tập 10 - Trang 1255-1266 - 2003
Laurent Meijer1,2, Alexios-Leandros Skaltsounis3, Prokopios Magiatis3, Panagiotis Polychronopoulos3, Marie Knockaert1, Maryse Leost1, Xiaozhou P. Ryan2, Claudia Alin Vonica4, Ali Brivanlou4, Rana Dajani5, Claudia Crovace6, Cataldo Tarricone6, Andrea Musacchio6, S.Mark Roe5, Laurence Pearl5, Paul Greengard2
1C.N.R.S., Cell Cycle Group, Station Biologique, B.P. 74, 29682 Roscoff cedex, Bretagne, France
2Laboratory of Molecular & Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 USA
3Division of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, University of Athens, Panepistimiopolis Zografou, GR-15771 Athens, Greece
4Laboratory of Molecular Embryology, The Rockefeller University, 1230 York Avenue, New York, NY 10021 USA
5Centre for Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, United Kingdom
6Structural Biology Unit, Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti 435, 20141 Milano, Italy

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