GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy

Cell Death and Differentiation - Tập 28 Số 8 - Trang 2333-2350 - 2021
Yinshuang Li1, Ying Yuan1, Zhidong Huang2, Hui Chen1, Ruilong Lan3, Zeng Wang3, Kunmei Lai1, Hong Chen4, Zhimin Chen1, Zhenhuan Zou1, Huabin Ma5, Hui‐Yao Lan6, Tak W. Mak7, Yanfang Xu1
1Department of Nephrology, Blood Purification Research Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China
2Laboratory Animal Center, Fujian Medical University, Fuzhou, China
3Central Laboratory, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China
4Department of Pathology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China
5State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China
6Department of Medicine & Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China
7Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

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