GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2
Zhi-Wei Li1, Beicheng Sun2, Ting Gong1, Sheng Guo1,3, Jianhua Zhang1,4, Junlong Wang1, Atsushi Sugawara5, Meisheng Jiang6, Junjun Yan7, Alexandra Gurary8, Xin Zheng1, Bifeng Gao9, Shu-Yuan Xiao10,11, Wenlian Chen12, Chi Ma1, Christine Farrar13, Chenjun Zhu1, Owen T.M. Chan14, Can Xin1, Andrew Winnicki1
1Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii
2Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China
3Department of Endocrine, Genetics and Metabolism, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China
4Department of Pediatrics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
5Institute for Biogenesis Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii
6Department of Molecular and Medical Pharmacology, University of California, Los Angeles, California
7Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
8Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii
9Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado
10Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
11Department of Pathology, University of Chicago, Chicago, Illinois
12Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii
13The Microscopy, Imaging, and Flow Cytometry Shared Resource, University of Hawaii Cancer Center, Honolulu, Hawaii
14Pathology Core, University of Hawaii Cancer Center, Honolulu, Hawaii
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Gastroenterology
Tập 156
2297-2312
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